US3989816A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Vehicle composition containing 1-substituted azacycloheptan-2-ones
Assignee: Discovery Therapeutics Inc
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Filing: 1975-06-19
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Granted: 1976-11-02
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Expires: 1995-06-19
Abstract
Abstract There is disclosed an improved method for topically administering a physiologically active agent to a human or animal by dissolving an effective amount of the agent in a carrier containing suitable amounts of 1-substituted-azacycloheptan-2-one, as defined herein, and contacting the skin or other membranes of the human or animal with the resulting composition, whereby penetration of the skin or membranes is enhanced.
Inventors
- 👤 Vithal Jagannath Rajadhyaksha
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 10:42
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K47/00; A61K47/06; A61K47/22; A61K8/00; A61K8/18; A61K8/30; A61K8/49; A61K8/4906; A61Q; A61Q17/00; A61Q17/005; A61Q17/04; A61Q19/00; A61F; A61F5/00; A61F5/41; A61F2005/415; A61Q17/02
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
90 words
A method for enhancing the penetration of physiologically active agents through human and animal body skin and membranes comprising administering to a human or animal a composition comprising an effective amount of said agent and a non-toxic, effective membrane penetrating amount of a compound having the formula ##SPC2## wherein R' is selected from the group consisting of H and alkyl having 1-4 carbon atoms, R is selected from the group consisting of an alkyl of 1-18 carbon atoms and phenyl and n is 0 or a positive integer from 1-10.
Claim 2
Independent Claim
90 words
A method for enhancing the penetration of physiologically active agents through human and animal body skin and membranes comprising administering to a human or animal a composition comprising an effective amount of said agent and a non-toxic, effective membrane penetrating amount of a compound having the formula ##SPC2## wherein R' is selected from the group consisting of H and alkyl having 1-4 carbon atoms, R is selected from the group consisting of an alkyl of 1-18 carbon atoms and phenyl and n is 0 or a positive integer from 1-10.
Claim 3
Dependent Claim
14 words
The method of claim 1 wherein the physiologically active agent is an antibacterial agent.
Claim 4
Dependent Claim
12 words
The method of claim 2, wherein the antibacterial agent is an antibiotic.
Claim 5
Dependent Claim
23 words
The method of claim 3 wherein the antibiotic is selected from the group consisting of lincomycin, clindamycin, erythromycin and pharmaceutically useful salts thereof.
Claim 6
Dependent Claim
15 words
The method of claim 1 wherein the physiologically active agent is a physiologically active steroid.
Claim 7
Dependent Claim
14 words
The method of claim 1 wherein the physiologically active agent is an antifungal agent.
Claim 8
Dependent Claim
12 words
The method of claim 1 wherein the physiologically active agent is iododeoxyuridine.
Claim 9
Dependent Claim
13 words
The method of claim 1 wherein the physiologically active agent is a sunscreen.
Claim 10
Dependent Claim
16 words
The method of claim 8 wherein the sunscreen is paraaminobenzoic acid or an active derivative thereof.
Claim 11
Dependent Claim
12 words
The method of claim 1 wherein the physiologically active agent is 5-fluorouracil.
Claim 12
Dependent Claim
13 words
The method of claim 1 wherein the physiologically active agent is an allergen.
References Cited (Backward Citations)
US3551554A
Cited
US3891757A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-11-02 | 1980-05-03 | 1980-11-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-11-02 | 1984-05-03 | 1984-11-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-11-02 | 1988-05-03 | 1988-11-02 | $7700.00 | Window Closed / Lapsed |