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US4409550A
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NMR Sodium images
Assignee: Harvard University
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Filing: 1981-05-15
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Granted: 1983-10-11
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Expires: 2001-05-15
Abstract
Abstract Apparatus for producing a sodium NMR image of sodium-containing biological tissue including an NMR pulse spectrometer capable of providing a plurality of simultaneous observation pulses and changing magnetic field gradients in order to produce an image, and sodium-23 nucleus selector means connected to said spectrometer.
Inventors
- 👤 Eric T. Fossel
- 👤 Jean L. Delayre
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 22:27
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/44; G01R33/48; G01R33/4828
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
103 words
Apparatus for producing a sodium NMR image of sodium-containing biological tissue having a physical characteristic capable of fluctuation, said apparatus comprising an NMR pulse spectrometer capable of providing a plurality of observation pulses and changing magnetic field gradients for producing an image, sodium-23 nucleus selector means connected to said spectrometer, sensing means for sensing said physical characteristic and providing an output signal, and triggering means responsive to said sensing means output signal and connected to said spectrometer for triggering said spectrometer to produce said observation pulses at a selected point in the course of said fluctuation of said physical characteristic of said tissue.
Claim 2
Dependent Claim
103 words
Apparatus for producing a sodium NMR image of sodium-containing biological tissue having a physical characteristic capable of fluctuation, said apparatus comprising an NMR pulse spectrometer capable of providing a plurality of observation pulses and changing magnetic field gradients for producing an image, sodium-23 nucleus selector means connected to said spectrometer, sensing means for sensing said physical characteristic and providing an output signal, and triggering means responsive to said sensing means output signal and connected to said spectrometer for triggering said spectrometer to produce said observation pulses at a selected point in the course of said fluctuation of said physical characteristic of said tissue.
Claim 3
Dependent Claim
11 words
The apparatus of claim 1 wherein said tissue is a heart.
Claim 4
Dependent Claim
36 words
The apparatus of claim 1 wherein said triggering means further includes time delay means for triggering said spectrometer to produce said observation pulses after a predetermined time delay following receipt of said sensing means output signal.
Claim 5
Dependent Claim
59 words
The apparatus of claim 1 wherein said fluctuation comprises repetition of a cycle and said triggering means further includes multiple pulse means for triggering said spectrometer to produce a plurality of groups of said observation pulses within one said cycle, whereby information is provided relating points in said cycle with changes in the NMR sodium image of said tissue.
Claim 6
Dependent Claim
31 words
The apparatus of claim 2 wherein said fluctuation is the cardiac cycle and said selected point in the course of said fluctuation is systole, which is indicated by a pressure wave.
Claim 7
Dependent Claim
15 words
The apparatus of claim 2 wherein said observation pulses are produced at systole and diastole.
References Cited (Backward Citations)
US4354499A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-10-10 | 1987-04-11 | 1987-10-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-10-10 | 1991-04-11 | 1991-10-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-10-10 | 1995-04-11 | 1995-10-11 | $7700.00 | Window Closed / Lapsed |