US4407757A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Aralkyl carboxylic acid compounds
Assignee: Takeda Pharmaceutical Co Ltd
•
Filing: 1980-12-31
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Granted: 1983-10-04
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Expires: 2000-12-31
Abstract
Abstract Novel compounds of the formulae ##STR1## wherein R represents lower alkyl or lower alkoxy, A represents --CH 2 --, --CO-- or ##STR2## n represents an integer of 1 to 8, X represents hydrogen or hydroxyl which may be protected and Y represents hydroxyl which may be protected, and their esters show an excellent action on the lysosomal membranes of cells, and exhibit excellent pharmacological activities such as physiologic host defense control activity, especially immuno-potentiating activity.
Inventors
- 👤 Hiroshi Morimoto
- 👤 Isuke Imada
- 👤 Masazumi Watanabe
- 👤 Mitsuru Kawada
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:08
CPC Classifications
C; C07; C07C; C07C66/00; C07C37/00; C07C37/001; C07C37/002; C07C37/50; C07C39/00; C07C39/02; C07C39/11; C07C45/00; C07C45/51; C07C45/54; C07C45/61; C07C45/67; C07C45/673; C07C46/00; C07C46/02; C07C46/06; C07C49/00; C07C49/76; C07C49/82; C07C49/84; C07C50/00; C07C50/26; C07C50/28; C07C50/38; C07C59/00; C07C59/40; C07C59/42; C07C59/52; C07C59/58; C07C59/64; C07C59/76; C07C59/90; C07C65/00; C07C65/32; C07C65/40
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
87 words
A compound of the formula ##STR15## wherein R represents alkyl of 1-4 carbon atoms or alkoxy of 1-4 carbon atoms, A represents --CH 2 --, --CO-- or ##STR16## B represents --CH 2 -- or --CO--, n represents an integer of 1 to 8, X represents hydrogen or hydroxyl and Y represents hydroxyl, or the corresponding ester with methanol at the function shown by --B--OH when B is --CO--, or the corresponding ester with acetic acid at the function shown by --B--OH when B is --CH 2 --.
Claim 2
Dependent Claim
87 words
A compound of the formula ##STR15## wherein R represents alkyl of 1-4 carbon atoms or alkoxy of 1-4 carbon atoms, A represents --CH 2 --, --CO-- or ##STR16## B represents --CH 2 -- or --CO--, n represents an integer of 1 to 8, X represents hydrogen or hydroxyl and Y represents hydroxyl, or the corresponding ester with methanol at the function shown by --B--OH when B is --CO--, or the corresponding ester with acetic acid at the function shown by --B--OH when B is --CH 2 --.
Claim 3
Dependent Claim
13 words
A compound as claimed in claim 1, wherein A is --CH 2 --.
Claim 4
Dependent Claim
11 words
A compound as claimed in claim 1, wherein A is --CO--.
Claim 5
Dependent Claim
11 words
A compound as claimed in claim 1, wherein A is ##STR17##
Claim 6
Dependent Claim
13 words
A compound as claimed in claim 1, wherein B is --CH 2 --.
Claim 7
Dependent Claim
11 words
A compound as claimed in claim 1, wherein B is --CO--.
Claim 8
Dependent Claim
15 words
A compound as claimed in claim 1, wherein R is alkyl of 1-4 carbon atoms.
Claim 9
Dependent Claim
11 words
A compound as claimed in claim 7, wherein R is methyl.
Claim 10
Dependent Claim
15 words
A compound as claimed in claim 1, wherein R is alkoxy of 1-4 carbon atoms.
Claim 11
Dependent Claim
15 words
A compound as claimed in claim 6, wherein R is alkyl of 1-4 carbon atoms.
Claim 12
Dependent Claim
15 words
A compound as claimed in claim 6, wherein R is alkoxy of 1-4 carbon atoms.
Claim 13
Dependent Claim
12 words
A compound as claimed in claim 9, wherein the R is methoxy.
Claim 14
Dependent Claim
13 words
A compound as claimed in claim 1, wherein n is 4 or 5.
Claim 15
Dependent Claim
11 words
A compound as claimed in claim 10, wherein R is methyl.
Claim 16
Dependent Claim
11 words
A compound as claimed in claim 11, wherein R is methoxy.
Claim 17
Dependent Claim
13 words
A compound as claimed in claim 6, wherein X and Y are hydroxyl.
Claim 18
Dependent Claim
13 words
A compound as claimed in claim 6, wherein n is 4 or 5.
Claim 19
Dependent Claim
25 words
A compound as claimed in claim 6, wherein the compound is in the form of an ester with methanol at the function shown by --B--OH.
Claim 20
Dependent Claim
26 words
A compound as claimed in claim 5, wherein the compound is in the form of an ester with acetic acid at the function shown by --B--OH.
Claim 21
Dependent Claim
10 words
The compound as claimed in claim 1, namely 10-(2'-hydroxy-3',4'-dimethoxy-6'-methylphenyl)decanoic acid.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-10-03 | 1987-04-04 | 1987-10-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-10-03 | 1991-04-04 | 1991-10-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-10-03 | 1995-04-04 | 1995-10-04 | $7700.00 | Window Closed / Lapsed |