Patent US4400518A successfully refreshed from Google Patents.
US4400518A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Composition of matter and process
Assignee: Pharmacia and Upjohn Co
•
Filing: 1982-02-08
•
Granted: 1983-08-23
•
Expires: 2002-02-08
Abstract
Abstract Novel antibacterially-active compound, 1,2,8,8a-cyclopropa[c]-benzo[1,2-b:-4,3-b']dipyrol-4(5H)one, prepared by a novel chemical process. This compound, as well as antibacterially-active intermediates, can be used to eradicate or control susceptible bacteria, for example, B. subtilis, K. pneumonia, S. lutea, S. aureus, and M. avium.
Inventors
- 👤 Wendell Wierenga
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 13:23
CPC Classifications
C; C07; C07D; C07D487/00; C07D487/02; C07D487/06; C07C; C07C205/00; C07C205/27; C07C205/35; C07C205/36; C07C205/37; C07C309/00; C07C309/63; C07C309/64; C07C309/65; C07C309/66; C07D209/00; C07D209/02; C07D209/04; C07D209/10; C07D209/12
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
111 words
A compound of the formula wherein R 2 and R 3 are H, alkyl of from 1 to 5 carbon atoms, inclusive, and phenyl; R 4 is selected from the group consisting of SO 2 R 2 , SO 2 CH 2 CO phenyl, CO 2 CH 2 Z where Z is selected from the group consisting of CH 2 I, CCl 3 , CH 2 SO 2 R 2 , Ph (phenyl), and fluoroenylmethyl, and X is selected from the group consisting of OSO 2 R 2 , Cl, Br, and I, with the proviso that R 2 can not be H when it is adjacent to SO 2 .
Claim 2
Dependent Claim
111 words
A compound of the formula wherein R 2 and R 3 are H, alkyl of from 1 to 5 carbon atoms, inclusive, and phenyl; R 4 is selected from the group consisting of SO 2 R 2 , SO 2 CH 2 CO phenyl, CO 2 CH 2 Z where Z is selected from the group consisting of CH 2 I, CCl 3 , CH 2 SO 2 R 2 , Ph (phenyl), and fluoroenylmethyl, and X is selected from the group consisting of OSO 2 R 2 , Cl, Br, and I, with the proviso that R 2 can not be H when it is adjacent to SO 2 .
Claim 3
Dependent Claim
22 words
A compound of the formula ##STR2## wherein R 2 , R 3 , and R 4 are as defined in claim 1.
Claim 4
Dependent Claim
77 words
A compound of the formula ##STR3## wherein R 1 is selected from the group consisting of CH 3 --, --CH 2 Ph, CH 2 ═CHCH 2 --, --CH 2 SCH 3 , --CH 2 OCH 3 , CH 2 OCH 2 CH 2 OCH 3 , --CH 2 CCl 3 , and --CH 2 CH 2 Si(R 2 ) 3 ; and R 2 , R 3 , and R 4 are as defined in claim 2.
Claim 5
Dependent Claim
10 words
A compound, according to claim 1, having the formula ##STR4##
Claim 6
Dependent Claim
10 words
A compound, according to claim 2, having the formula ##STR5##
Claim 7
Dependent Claim
10 words
A compound, according to claim 3, having the formula ##STR6##
References Cited (Backward Citations)
US4169888A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-08-22 | 1987-02-21 | 1987-08-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-08-22 | 1991-02-21 | 1991-08-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-08-22 | 1995-02-21 | 1995-08-23 | $7700.00 | Window Closed / Lapsed |