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Nucleosidic phosphorylating agent and methods

Assignee: Genentech Inc
•
Filing: 1981-08-20
•
Granted: 1983-07-12
•
Expires: 2001-08-20
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Abstract

Abstract Compounds of the formula ##STR1## where R is a base labile substituted-phenyloxy protecting group, are useful as phosphorylating reagents in the synthesis of oligonucleotides by a phosphotriester method.

Inventors

  • 👤 Roberto Crea

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-03 15:55
CPC Classifications
C; C07; C07H; C07H21/00; C07F; C07F9/00; C07F9/02; C07F9/06; C07F9/08; C07F9/09; C07F9/14; C07F9/1406; Y; Y02; Y02P; Y02P20/00; Y02P20/50; Y02P20/55

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 14 words
A compound of structure ##STR8## where R is a base labile phenyloxy protecting group.
Claim 2
Dependent Claim 14 words
A compound of structure ##STR8## where R is a base labile phenyloxy protecting group.
Claim 3
Dependent Claim 22 words
A compound according to claim 1 wherein R is selected from the group consisting of p-chlorophenyloxy, o-chlorophenyloxy, 2,4-dichlorophenyloxy, p-nitrophenyloxy and p-methoxyphenyloxy groups.
Claim 4
Dependent Claim 5 words
The compound of structure ##STR9##
Claim 5
Dependent Claim 5 words
The compound of structure ##STR9##

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1986-07-11 1987-01-10 1987-07-12 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1990-07-11 1991-01-10 1991-07-12 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1994-07-11 1995-01-10 1995-07-12 $7700.00 Window Closed / Lapsed

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