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US4390026A Expired / Lapsed US ⏱️ 0.0 years remaining

Ultrasonic therapy applicator that measures dosage

Assignee: United States Department of Health and Human Services
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Filing: 1981-05-22
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Granted: 1983-06-28
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Expires: 2001-05-22
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Abstract

Abstract An ultrasonic therapy applicator wherein therapeutic heating is provided by creating a diffuse ultrasonic field in a liquid, such as water, in a tank in which living tissue may be immersed. The diffuse acoustic energy is produced by frequency-modulating the driving ultrasonic frequency in a band employing "white noise" modulation. The apparatus consists of a reverberation tank suspended from a support by four wires. The support is used to mount a transducer, a hydrophone, a specimen holder and a stirrer. The tank is surrounded by a temperature bath. The hydrophone is used for measuring decay rates. The transducer is acoustically matched to the water. Ultrasound is coupled from the transducer via an ellipsoidal vertical reflector vertically aligned below the acoustic window of the transducer. To calibrate integral dosage a temperature sensing probe is used, of the differential temperature analysis type. The probe consists of two thermocouples, one embedded at the center of a RHO-C rubber sphere and the other mounted outside near the sphere. Measuring the differential temperature signal that results when the sphere is irradiated enables determination of the acoustic energy density. The RHO-C rubber has an acoustic impedance nearly equal to that of water, and therefore the probe does not significantly change the exposure field. The absorption coefficient of the rubber is satisfactorily high. Also, the RHO-C rubber holds its thermocouple firmly in place during comparative measurements. The probe minimizes disruption of the exposure and has an omnidirectional response.

Inventors

  • 👤 Chris L. Christman

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-06 15:16
CPC Classifications
G; G10; G10K; G10K11/00; G10K11/18; G10K11/20; A; A61; A61N; A61N7/00; A61N7/02; G01; G01H; G01H3/00; G01H3/10

Claims Analysis

Total Claims: 18
Claim 1
Independent Claim 145 words
An apparatus for measuring the integral dose ε applied for a time period t to a body of living tissue undergoing exposure to ultrasonic wave energy comprising a reverberation tank containing liquid, transducer means coupled to said liquid, a hydrophone mounted so as to be immersed in the liquid, circuit means to drive the transducer means to generate ultrasonic wave energy, means to create a diffuse field in the liquid in the tank, means to expose the living tissue to the liquid, means to measure the total power P absorbed within the tank, and circuit means connected to said hydrophone to measure the decay rates D s and D f of ultrasonic wave energy pulses respectively with the tissue in the liquid and with the tissue removed from the liquid, whereby the integral dose ε can be computed according to the equation: ε=Pt(D.sub.2 -D.sub.f)/D.sub.s .
Claim 2
Independent Claim 145 words
An apparatus for measuring the integral dose ε applied for a time period t to a body of living tissue undergoing exposure to ultrasonic wave energy comprising a reverberation tank containing liquid, transducer means coupled to said liquid, a hydrophone mounted so as to be immersed in the liquid, circuit means to drive the transducer means to generate ultrasonic wave energy, means to create a diffuse field in the liquid in the tank, means to expose the living tissue to the liquid, means to measure the total power P absorbed within the tank, and circuit means connected to said hydrophone to measure the decay rates D s and D f of ultrasonic wave energy pulses respectively with the tissue in the liquid and with the tissue removed from the liquid, whereby the integral dose ε can be computed according to the equation: ε=Pt(D.sub.2 -D.sub.f)/D.sub.s .
Claim 3
Dependent Claim 28 words
The dose measuring apparatus of claim 1, and wherein the means to create the diffuse field includes means to frequency-modulate the driving electrical wave energy with white noise.
Claim 4
Dependent Claim 37 words
The dose measuring apparatus of claim 1, and wherein the means to create the diffuse field includes acoustic reflector means mounted in the tank adjacent to the transducer means in a substantially vertically aligned position relative thereto.
Claim 5
Dependent Claim 35 words
The dose measuring apparatus of claim 1, and wherein the transducer means includes a depending coupling portion and acoustic reflector means mounted in the tank subjacent to said coupling portion and substantially vertically aligned therewith.
Claim 6
Dependent Claim 42 words
The dose measuring apparatus of claim 1, and wherein the means to create the diffuse field includes acoustic reflector means mounted in the tank subjacent to the transducer means and being shaped to scatter the direct wave produced by the transducer means.
Claim 7
Dependent Claim 35 words
The dose measuring apparatus of claim 1, and wherein the means to create the diffuse field includes a substantially acoustically reflective vertically elongated body mounted subjacent to the transducer means substantially in vertical alignment therewith.
Claim 8
Dependent Claim 35 words
The dose measuring apparatus of claim 6, and wherein said transducer means includes a depending coupling portion provided with an acoustically transparent output membrane located above and substantially in vertical alignment with said reflective body.
Claim 9
Dependent Claim 38 words
The dose measuring apparatus of claim 7, and wherein said coupling portion comprises an axially depending extension forming a reservoir, with coupling liquid substantially filling said reservoir, and wherein said membrane forms the bottom end of said reservoir.
Claim 10
Dependent Claim 27 words
The dose measuring apparatus of claim 8, and wherein said reflective body is substantially ellipsoidal in shape, with its major axis substantially aligned with said depending extension.
Claim 11
Dependent Claim 74 words
The dose measuring apparatus of claim 8, and wherein said transducer means comprises a main holder assembly, a piezoelectric driving member secured in said main holder assembly in driving relationship to said coupling portion, depending support rod means rigidly connected to said main holder assembly and extending beneath said reservoir, and means rigidly mounting said reflective body on the lower end portion of said support rod means substantially in vertical alignment with said reservoir.
Claim 12
Dependent Claim 29 words
The dose measuring apparatus of claim 1, and wherein said means to measure the total power P comprises temperature-sensing means mounted in the tank and immersed in the liquid.
Claim 13
Dependent Claim 34 words
The dose measuring apparatus of claim 11, and wherein said temperature-sensing means comprises depending support means secured to the tank, and a thermocouple assembly secured to the lower portion of said depending support means.
Claim 14
Dependent Claim 60 words
The dose measuring apparatus of claim 12, and wherein said thermocouple assembly comprises an acoustically absorbing body, a first thermocouple mounted in the interior of said acoustically absorbing body, a reference thermocouple mounted on said support means outside of and adjacent to said acoustically absorbing body in thermally-conductive relation to said liquid, and circuit means differentially connecting the two thermocouples.
Claim 15
Dependent Claim 17 words
The dose measuring apparatus of claim 13, and wherein said acoustically absorbing body comprises RHO-C rubber material.
Claim 16
Dependent Claim 29 words
The dose measuring apparatus of claim 14, and wherein said acoustically absorbing body is substantially spherical and said first thermocouple is embedded substantially centrally in the acoustically absorbing body.
Claim 17
Dependent Claim 40 words
The dose measuring apparatus of claim 1, and wherein said apparatus comprises a main stationary support means, and a plurality of spaced suspension wires supportingly connecting said tank to said main support means for minimizing acoustic losses in said tank.
Claim 18
Dependent Claim 55 words
The dose measuring apparatus of claim 1, and an outer receptacle, stationary main support means, means suspending said tank from said main support means in said outer receptacle to define a separation space therebetween, means to circulate temperature-controlled liquid in said separation space, and means to at times drain said temperature-controlled liquid from said space.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1986-06-27 1986-12-27 1987-06-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1990-06-27 1990-12-27 1991-06-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1994-06-27 1994-12-27 1995-06-28 $7700.00 Window Closed / Lapsed

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