Patent US4388301A successfully refreshed from Google Patents.
US4388301A
Expired / Lapsed
US
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Method and composition for treating acne
Assignee: William H Rorer Inc
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Filing: 1982-04-30
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Granted: 1983-06-14
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Expires: 2002-04-30
Abstract
Abstract A method of treating skin conditions utilizing a deodorized composition containing soluble polysulfide compounds and the composition therefor.
Inventors
- 👤 Robert W. Klein
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 02:44
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/23; A61K33/00; A61K33/04; A61K33/06; A61K33/08; A61K33/10; A61K33/12; A61Q; A61Q19/00; A61Q19/008
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
171 words
A method for treating acne and oily skin in a patient in need thereof which comprises topically administering to said patient an effective amount of a composition comprising about 1-20% by weight of total composition of an inorganic polysulfide compound in a carrier comprising a sorbent powder, said polysulfide comprising a sulfurated lime solution an inorganic metallic di- or polysulfide compound of the formula M 2 S n containing unbranched [S n ] 2- ions, where M designates a metal and n is any number from 2 to the maximum value of n, which polysulfide upon topical administration itself has an objectionable odor, said powder comprising about 10-70% by weight of at least one montmorillonite clay based on the weight of the total composition and about 2-30% by weight of attapulgite based on the weight of the total composition, said powder being present in an amount to deodorize said composition, to absorb and adsorb the skin oils and to release an effective amount of said polysulfide compound to treat said patient.
Claim 2
Independent Claim
171 words
A method for treating acne and oily skin in a patient in need thereof which comprises topically administering to said patient an effective amount of a composition comprising about 1-20% by weight of total composition of an inorganic polysulfide compound in a carrier comprising a sorbent powder, said polysulfide comprising a sulfurated lime solution an inorganic metallic di- or polysulfide compound of the formula M 2 S n containing unbranched [S n ] 2- ions, where M designates a metal and n is any number from 2 to the maximum value of n, which polysulfide upon topical administration itself has an objectionable odor, said powder comprising about 10-70% by weight of at least one montmorillonite clay based on the weight of the total composition and about 2-30% by weight of attapulgite based on the weight of the total composition, said powder being present in an amount to deodorize said composition, to absorb and adsorb the skin oils and to release an effective amount of said polysulfide compound to treat said patient.
Claim 3
Dependent Claim
14 words
The method of claim 1, wherein said polysulfide compound is a sulfurated lime solution.
Claim 4
Dependent Claim
23 words
The method of claim 1, wherein said polysulfide compound is selected from the group consisting of alkali metal and alkaline earth metal polysulfides.
Claim 5
Dependent Claim
15 words
The method according to claim 1, including a pharmaceutically acceptable surfactant and a lower alkanol.
Claim 6
Dependent Claim
22 words
The method of claim 1, wherein said montmorillonite clay is selected from the group consisting of bentonite, hectorite, smectite, kaolin and saponite.
Claim 7
Dependent Claim
20 words
The method of claim 1, including at least one filler selected from the group consisting of talc and calcium carbonate.
Claim 8
Dependent Claim
27 words
The method of claim 1, including an effective amount of a compound selected from the group consisting of benzoyl peroxide, retinoic acid, erythromycin, salicylic acid or resorcinol.
Claim 9
Dependent Claim
12 words
The method according to claim 1, wherein said polysulfide is calcium polysulfide.
Claim 10
Independent Claim
106 words
A method of treating oily skin in a patient in need thereof which comprises topically administering to said patient an effective amount of a composition comprising 2-10% by weight of a sulfurated lime solution and finely divided powder containing montmorillonite clay powder in an amount of about 10-70% by weight based on the weight of the total composition and about 2-30% by weight of attapulgite based on the weight of the total composition, whereby said clays are present in an amount sufficient to deodorize said composition, to absorb and adsorb skin oils and to release an effective amount of sulfurated lime solution to treat said patient.
Claim 11
Independent Claim
106 words
A method of treating oily skin in a patient in need thereof which comprises topically administering to said patient an effective amount of a composition comprising 2-10% by weight of a sulfurated lime solution and finely divided powder containing montmorillonite clay powder in an amount of about 10-70% by weight based on the weight of the total composition and about 2-30% by weight of attapulgite based on the weight of the total composition, whereby said clays are present in an amount sufficient to deodorize said composition, to absorb and adsorb skin oils and to release an effective amount of sulfurated lime solution to treat said patient.
Claim 12
Dependent Claim
149 words
An anti-acne and anti-seborrheic pharmaceutical composition for topical administration comprising about 1-20% by weight of total composition of an inorganic polysulfide compound in a carrier comprising a sorbent powder, said polysulfide comprising a sulfurated lime solution an inorganic metallic di- or polysulfide compound of the formula M 2 S n containing unbranched [Sn] 2- ions, where M designates a metal and n is any number from 2 to the maximum value of n, which polysulfide upon topical administration itself has an objectionable odor, said powder comprising about 10-70% by weight of a montmorillonite clay based on the weight of the total composition and about 2-30% by weight of attapulgite based on the weight of the total composition, said powder being present in an amount to deodorize said composition, to absorb and adsorb the skin oils and to release an effective amount of said polysulfide compound to treat said patient.
Claim 13
Dependent Claim
149 words
An anti-acne and anti-seborrheic pharmaceutical composition for topical administration comprising about 1-20% by weight of total composition of an inorganic polysulfide compound in a carrier comprising a sorbent powder, said polysulfide comprising a sulfurated lime solution an inorganic metallic di- or polysulfide compound of the formula M 2 S n containing unbranched [Sn] 2- ions, where M designates a metal and n is any number from 2 to the maximum value of n, which polysulfide upon topical administration itself has an objectionable odor, said powder comprising about 10-70% by weight of a montmorillonite clay based on the weight of the total composition and about 2-30% by weight of attapulgite based on the weight of the total composition, said powder being present in an amount to deodorize said composition, to absorb and adsorb the skin oils and to release an effective amount of said polysulfide compound to treat said patient.
Claim 14
Dependent Claim
19 words
The composition according to claim 10, wherein said polysulfide compound is in the form of a sulfurated lime solution.
Claim 15
Dependent Claim
24 words
The composition according to claim 10, wherein said polysulfide compound is selected from the group consisting of alkali metal and alkaline earth metal polysulfides.
Claim 16
Dependent Claim
15 words
The composition according to claim 10, including a pharmaceutically acceptable surfactant and a lower alkanol.
Claim 17
Dependent Claim
23 words
The composition according to claim 10, wherein said montmorillonite clay is selected from the group consisting of bentonite, hectorite, smectite, kaolin and saponite.
Claim 18
Dependent Claim
22 words
The composition according to claim 10, wherein said composition includes one filler selected from the group consisting of talc and calcium carbonate.
Claim 19
Dependent Claim
28 words
The composition according to claim 10 including an effective amount of a compound selected from the group consisting of benzoyl peroxide, erythromycin, retinoic acid, salicylic acid or resorcinol.
Claim 20
Dependent Claim
22 words
The composition according to claim 10 includes an antibiotic agent in the amount of about 1-6% by weight of the total composition.
Claim 21
Dependent Claim
12 words
The composition according to claim 10, wherein said polysulfide is calcium polysulfide.
References Cited (Backward Citations)
US1800502A
Cited
US2156790A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-06-13 | 1986-12-13 | 1987-06-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-06-13 | 1990-12-13 | 1991-06-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-06-13 | 1994-12-13 | 1995-06-14 | $7700.00 | Window Closed / Lapsed |