US4388236A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Enkephalin-like compounds in bovine adrenal medulla
Assignee: Hoffmann La Roche Inc
•
Filing: 1982-05-04
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Granted: 1983-06-14
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Expires: 2002-05-04
Abstract
Abstract Enkephalin-like compounds having opiate agonist activity and useful as analgesic agents are extracted from bovine adrenal glands.
Inventors
- 👤 Stanley Stein
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 11:32
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/665; A; A61; A61K; A61K38/00; Y; Y10; Y10S; Y10S530/00; Y10S530/827; Y10S530/854
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
33 words
A peptide compound endogenous in mammalian adrenal glands, essentially free of other endogenous peptides and having the following amino acid sequence: ##STR9## and the pharmaceutically acceptable acid addition salts or base salts thereof.
Claim 2
Dependent Claim
33 words
A peptide compound endogenous in mammalian adrenal glands, essentially free of other endogenous peptides and having the following amino acid sequence: ##STR9## and the pharmaceutically acceptable acid addition salts or base salts thereof.
Claim 3
Dependent Claim
32 words
A peptide compound endogenous in mammalian adrenal glands, essentially free of other endogenous peptides and having the following acid sequence: ##STR10## and the pharmaceutically acceptable acid addition salts or base salts thereof.
Claim 4
Dependent Claim
32 words
A peptide compound endogenous in mammalian adrenal glands, essentially free of other endogenous peptides and having the following acid sequence: ##STR10## and the pharmaceutically acceptable acid addition salts or base salts thereof.
Claim 5
Dependent Claim
33 words
A peptide compound endogenous in mammalian adrenal glands, essentially free of other endogenous peptides and having the following amino acid sequence: ##STR11## and the pharmaceutically acceptable acid addition salts or base salts thereof.
Claim 6
Dependent Claim
33 words
A peptide compound endogenous in mammalian adrenal glands, essentially free of other endogenous peptides and having the following amino acid sequence: ##STR11## and the pharmaceutically acceptable acid addition salts or base salts thereof.
Claim 7
Dependent Claim
33 words
A peptide compound endogenous in mammalian adrenal glands, essentially free of other endogenous peptides and having the following amino acid sequence: ##STR12## and the pharmaceutically acceptable acid addition salts or base salts thereof.
Claim 8
Dependent Claim
33 words
A peptide compound endogenous in mammalian adrenal glands, essentially free of other endogenous peptides and having the following amino acid sequence: ##STR12## and the pharmaceutically acceptable acid addition salts or base salts thereof.
Claim 9
Dependent Claim
31 words
A peptide compound endogenous in mammalian adrenal glands, essentially free of other endogenous peptides and having the following amino acid sequence: ##STR13## and the pharmaceutically acceptable salts or base salts thereof.
Claim 10
Dependent Claim
31 words
A peptide compound endogenous in mammalian adrenal glands, essentially free of other endogenous peptides and having the following amino acid sequence: ##STR13## and the pharmaceutically acceptable salts or base salts thereof.
Claim 11
Dependent Claim
32 words
A peptide compound endogenous in mammalian adrenal glands, essentially free of other endogenous peptides and having the following amino acid sequences: ##STR14## and the pharmaceutically acceptable acid addition salts or base thereof.
Claim 12
Dependent Claim
32 words
A peptide compound endogenous in mammalian adrenal glands, essentially free of other endogenous peptides and having the following amino acid sequences: ##STR14## and the pharmaceutically acceptable acid addition salts or base thereof.
Claim 13
Dependent Claim
33 words
A peptide compound endogenous in mammalian adrenal glands, essentially free of other endogenous peptides and having the following amino acid sequence: ##STR15## and the pharmaceutically acceptable acid addition salts or base salts thereof.
Claim 14
Dependent Claim
33 words
A peptide compound endogenous in mammalian adrenal glands, essentially free of other endogenous peptides and having the following amino acid sequence: ##STR15## and the pharmaceutically acceptable acid addition salts or base salts thereof.
References Cited (Backward Citations)
US4073885A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-06-13 | 1986-12-13 | 1987-06-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-06-13 | 1990-12-13 | 1991-06-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-06-13 | 1994-12-13 | 1995-06-14 | $7700.00 | Window Closed / Lapsed |