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US4385125A
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Method detecting ovulation by monitoring dodecanol concentration in saliva
Assignee: MONELL CHEMICAL CHEMICAL SENSES CENTER A CORP OF PA
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Filing: 1980-11-14
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Granted: 1983-05-24
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Expires: 2000-11-14
Abstract
Abstract Method for precisely ascertaining the time of ovulation by monitoring the concentration of alcohols in the range of C 10 -C 16 , particularly dodecanol. A spike in the concentration of such compound(s) is indicative of time of ovulation.
Inventors
- 👤 George Preti
- 👤 James G. Kostelc
- 👤 Joseph Tonzetich
- 👤 George R. Huggins
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 12:42
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; Y; Y10; Y10T; Y10T436/00; Y10T436/20; Y10T436/203332
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
72 words
A method of diagnosing ovulation in female mammals comprising the steps of: (a) monitoring the saliva of one of said mammals during the fertility cycle for a dodecanol occurring in the saliva of said mammals; and (b) providing an indicator means for qualitatively and quantitatively responding to variations in the concentration of said dodecanol in said saliva; whereby said means for indicating said variations in concentration diagnosis ovulation in said female mammal.
Claim 2
Independent Claim
72 words
A method of diagnosing ovulation in female mammals comprising the steps of: (a) monitoring the saliva of one of said mammals during the fertility cycle for a dodecanol occurring in the saliva of said mammals; and (b) providing an indicator means for qualitatively and quantitatively responding to variations in the concentration of said dodecanol in said saliva; whereby said means for indicating said variations in concentration diagnosis ovulation in said female mammal.
Claim 3
Dependent Claim
13 words
The method of claim 1 wherein said female mammal is a human female.
Claim 4
Dependent Claim
13 words
The method of claim 1 wherein said indicator is a gas chromograph-mass spectrometer.
Claim 5
Dependent Claim
31 words
The method of claim 1 wherein said method comprises the steps of incubating said saliva for a preselected period of time and monitoring the concentration of said dodecanol in said saliva.
Claim 6
Dependent Claim
23 words
The method of claim 4 wherein said preselected period of time is from between about 30 to 120 minutes at about 37° C.
Claim 7
Dependent Claim
18 words
The method of claim 1 wherein said indicator means responds to increases in the concentration of said dodecanol.
Claim 8
Dependent Claim
27 words
The method of claim 6 wherein said increases of concentration of said dodecanol represent at least a doubling of the concentration of said dodecanol in said saliva.
Claim 9
Dependent Claim
25 words
The method of claim 7 wherein said increases in dodecanol represent an increase of about four times the concentration of said dodecanol in said saliva.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-05-23 | 1986-11-22 | 1987-05-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-05-23 | 1990-11-22 | 1991-05-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-05-23 | 1994-11-22 | 1995-05-24 | $7700.00 | Window Closed / Lapsed |