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US4385049A Expired / Lapsed US ⏱️ 0.0 years remaining

Stable high internal phase ratio topical emulsions

Assignee: Amag Pharma USA Inc
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Filing: 1981-05-12
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Granted: 1983-05-24
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Expires: 2001-05-12
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Abstract

Abstract Delivery systems for topical preparations which are commercially stable. The emulsions are water-in-oil in which the water phase comprises at least 75% of the emulsion by volume. The emulsifier is a nonionic oil soluble straight or branched chain ester or combination thereof composition having at least two hydrogen bonding sites per molecule.

Inventors

  • 👤 Robert C. Cuca

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 18:50
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/02; A61K8/04; A61K8/06; A61K8/064; A61K47/00; A61K47/06; A61K47/08; A61K47/10; A61K47/14; A61K47/44; A61K8/18; A61K8/30; A61K8/33; A61K8/38; A61K8/39; A61K9/00; A61K9/0012; A61K9/0014; A61K9/10; A61K9/107; A61Q; A61Q15/00; A61Q17/00

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 50 words
Delivery systems for topical preparations which comprise nonlipoidal media in lipoidal media emulsions in which the nonlipoidal phase is at least 75% of the emulsion, the lipoidal phase containing nonionic oil soluble straight or branched chain ester or combinations thereof emulsifiers having at least two hydrogen bonding sites per molecule.
Claim 2
Dependent Claim 50 words
Delivery systems for topical preparations which comprise nonlipoidal media in lipoidal media emulsions in which the nonlipoidal phase is at least 75% of the emulsion, the lipoidal phase containing nonionic oil soluble straight or branched chain ester or combinations thereof emulsifiers having at least two hydrogen bonding sites per molecule.
Claim 3
Dependent Claim 63 words
Delivery systems for topical preparations which comprise nonlipoidal media in lipoidal media emulsions in which the nonlipoidal phase is at least 75% of the emulsion, the lipoidal phase comprises an oil whose viscosity is between approximately 6.7 and 68.7 centristokes and contains nonionic oil soluble straight or branched chain ester or combinations thereof emulsifiers having at least two hydrogen bonding sites per molecule.
Claim 4
Dependent Claim 63 words
Delivery systems for topical preparations which comprise nonlipoidal media in lipoidal media emulsions in which the nonlipoidal phase is at least 75% of the emulsion, the lipoidal phase comprises an oil whose viscosity is between approximately 6.7 and 68.7 centristokes and contains nonionic oil soluble straight or branched chain ester or combinations thereof emulsifiers having at least two hydrogen bonding sites per molecule.
Claim 5
Dependent Claim 13 words
The delivery systems of claim 1 wherein said lipoidal media comprises mineral oils.
Claim 6
Dependent Claim 13 words
The delivery systems of claim 1 wherein said lipoidal media comprises vegetable oils.
Claim 7
Dependent Claim 12 words
The delivery systems of claim 1 wherein said nonlipoidal media comprises water.
Claim 8
Dependent Claim 12 words
The delivery systems of claim 1 wherein said nonlipoidal media comprises glycerine.
Claim 9
Dependent Claim 12 words
The delivery systems of claim 1 wherein said nonlipoidal media comprises sorbitol.
Claim 10
Dependent Claim 12 words
The delivery systems of claim 1 wherein said emulsifiers comprise polyglycerol oleate.
Claim 11
Dependent Claim 12 words
The delivery systems of claim 1 wherein said emulsifiers comprise glycerol monoisosterate.

References Cited (Backward Citations)

US3536816A Cited
GB1415528A Cited
US4035513A Cited
US4337241A Cited
US4252796A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1986-05-23 1986-11-22 1987-05-24 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1990-05-23 1990-11-22 1991-05-24 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1994-05-23 1994-11-22 1995-05-24 $7700.00 Window Closed / Lapsed

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