US4380549A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Topical treatment of dry skin
Assignee: Individual
•
Filing: 1981-03-23
•
Granted: 1983-04-19
•
Expires: 2001-03-23
Abstract
Abstract Preventive as well as therapeutic treatment to alleviate the symptoms of disorders characterized by cracking, flaking, or scaling of the skin consisting of the topical application of a solution, lotion, gel, stick, powder, cream or ointment containing as active ingredients one or more hydroxy acid or its analogue is disclosed. The hydroxyacid and its analogues include free acid, amide, lactone, ester, anhydride, organic or inorganic salt form of hydroxymonocarboxylic acids, hydroxydicarboxylic acids, hydroxytricarboxylic acids and keto acids. The therapeutic composition may include one or more of the compounds present in the total amount of from 0.1 to 20 percent. Topical application to affected areas has been found to ameliorate dry skin conditions.
Inventors
- 👤 Eugene J. Van Scott
- 👤 Ruey J. Yu
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 15:59
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/185; A61K31/19; A61K31/16; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/36; A61K8/365; A61Q; A61Q19/00; A61Q19/007
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
106 words
A method for alleviating the symptoms of dry skin in humans comprising topically applying to involved areas of the human body an effective amount of at least one member selected from the group consisting of: ______________________________________
Glycolic Acid Malic Acid
Glucuronic Acid Mucic Acid
Galacturonic Acid Citric Acid
Gluconic Acid Saccharic Acid
Glucoheptonic Acid Tartaric Acid
α-Hydroxybutyric Acid
Tartronic Acid
α-Hydroxyisobutyric Acid
Isocitric Acid
α-Hydroxyisocaproic Acid
Dihydroxymaleic Acid
α-Hydroxyisovaleric Acid
Dihydroxytartaric Acid
β-Hydroxybutyric Acid
Dihydroxyfumaric Acid
[Lactic Acid]
β-Phenllactic Acid
Atrolactic Acid
Mandelic Acid
Galactonic Acid
Pantoic Acid
Glyceric Acid
______________________________________ or a salt thereof with an organic or inorganic alkali, in a pharmaceutically acceptable vehicle.
Claim 2
Independent Claim
106 words
A method for alleviating the symptoms of dry skin in humans comprising topically applying to involved areas of the human body an effective amount of at least one member selected from the group consisting of: ______________________________________
Glycolic Acid Malic Acid
Glucuronic Acid Mucic Acid
Galacturonic Acid Citric Acid
Gluconic Acid Saccharic Acid
Glucoheptonic Acid Tartaric Acid
α-Hydroxybutyric Acid
Tartronic Acid
α-Hydroxyisobutyric Acid
Isocitric Acid
α-Hydroxyisocaproic Acid
Dihydroxymaleic Acid
α-Hydroxyisovaleric Acid
Dihydroxytartaric Acid
β-Hydroxybutyric Acid
Dihydroxyfumaric Acid
[Lactic Acid]
β-Phenllactic Acid
Atrolactic Acid
Mandelic Acid
Galactonic Acid
Pantoic Acid
Glyceric Acid
______________________________________ or a salt thereof with an organic or inorganic alkali, in a pharmaceutically acceptable vehicle.
Claim 3
Dependent Claim
22 words
The method of claim 1 wherein said member is present in a concentration of from about 0.1 to 20 percent by weight.
Claim 4
Dependent Claim
26 words
The method of claim 1 wherein a plurality of said members are present in a total concentration of no more than about 15 percent by weight.
Claim 5
Dependent Claim
31 words
The method of claim 1 wherein said member is present as a salt with at least one base selected from the group consisting of ammonium hydroxide, sodium hydroxide and potassium hydroxide.
Claim 6
Independent Claim
55 words
A method for alleviating the symptoms of dry skin in humans comprising topically applying an effective amount of at least one member selected from the group consisting of: pyruvic acid, benzoylformic acid, β-phenylpyruvic acid, β-hydroxypyruvic acid and β-hydroxypyruvic acid phosphate or a salt thereof with an organic or inorganic alkali, in a pharmaceutically acceptable vehicle.
Claim 7
Independent Claim
55 words
A method for alleviating the symptoms of dry skin in humans comprising topically applying an effective amount of at least one member selected from the group consisting of: pyruvic acid, benzoylformic acid, β-phenylpyruvic acid, β-hydroxypyruvic acid and β-hydroxypyruvic acid phosphate or a salt thereof with an organic or inorganic alkali, in a pharmaceutically acceptable vehicle.
Claim 8
Dependent Claim
22 words
The method of claim 5 wherein said member is present in a concentration of from about 0.1 to 20 percent by weight.
Claim 9
Dependent Claim
26 words
The method of claim 5 wherein a plurality of said members are present in a total concentration of no more than about 15 percent by weight.
Claim 10
Dependent Claim
31 words
The method of claim 5 wherein said member is present as a salt with at least one base selected from the group consisting of ammonium hydroxide, sodium hydroxide and potassium hydroxide.
Claim 11
Independent Claim
70 words
A method for alleviating the symptoms of dry skin in humans comprising an effective amount of at least one member selected from the group consisting of: glyceric acid, gluconic acid, glucoheptonic acid, α-hydroxyisocaproic acid, α-hydroxyisovaleric acid, atrolactic acid, galatonic acid, isocitric acid, dihydroxymaleic acid, dehydroxytartaric acid, dihydroxyfumaric acid, benzoylformic acid, β-hydroxypyruvic acid, β-hydroxypyruvic acid phosphate, or a salt thereof with an organic or inorganic alkali in a pharmaceutically acceptable vehicle.
Claim 12
Independent Claim
70 words
A method for alleviating the symptoms of dry skin in humans comprising an effective amount of at least one member selected from the group consisting of: glyceric acid, gluconic acid, glucoheptonic acid, α-hydroxyisocaproic acid, α-hydroxyisovaleric acid, atrolactic acid, galatonic acid, isocitric acid, dihydroxymaleic acid, dehydroxytartaric acid, dihydroxyfumaric acid, benzoylformic acid, β-hydroxypyruvic acid, β-hydroxypyruvic acid phosphate, or a salt thereof with an organic or inorganic alkali in a pharmaceutically acceptable vehicle.
Claim 13
Dependent Claim
22 words
The method of claim 9 wherein said member is present in a concentration of from about 0.1 to 20 percent by weight.
Claim 14
Dependent Claim
26 words
The method of claim 9 wherein a plurality of said members are present in a total concentration of no more than about 15 percent by weight.
Claim 15
Dependent Claim
31 words
The method of claim 9 wherein said member is present as a salt with at least one base selected from the group consisting of ammonium hydroxide, sodium hydroxide and potassium hydroxide.
References Cited (Backward Citations)
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US3666863A
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US3793210A
Cited
US3879537A
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US4021572A
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-04-18 | 1986-10-18 | 1987-04-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-04-18 | 1990-10-18 | 1991-04-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-04-18 | 1994-10-18 | 1995-04-19 | $7700.00 | Window Closed / Lapsed |