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US4376787A Expired / Lapsed US ⏱️ 0.0 years remaining

Control of mastitis

Assignee: Ecolab Inc
•
Filing: 1979-12-03
•
Granted: 1983-03-15
•
Expires: 1999-12-03
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Abstract

Abstract A mastitis controlling method and composition based upon anionic surfactants of the formula R-AOx-M+ which generally includes organic sulfonates, sulfonic acids, phosphonates and phosphates, the composition being maintained in a pH range of 2.0 to 5.0 (preferably 2.1 to 4.0, and most preferably 2.5 to 3.5). Rapid kill of mastitis-causing gram positive and gram negative microorganisms is achieved in the practice of the instant method.

Inventors

  • 👤 Steven E. Lentsch
  • 👤 William Schmidt

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-29 08:32
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/66; A01; A01N; A01N41/00; A01N41/02; A01N41/04; A01N57/00; A01N57/10; A01N57/12; A01N57/14; A61K31/185; A61K9/00; A61K9/0012; A61K9/0041; Y; Y02; Y02A; Y02A50/00; Y02A50/30

Claims Analysis

Total Claims: 30
Claim 1
Independent Claim 120 words
A method for killing mastitis-causing gram negative organisms including Pseudomonas aeruginosa, Escherichia coli, or Klebsiella pneumoniae or gram positive organisms including Staphylococcus auereus on an animal's teats comprising the step of treating the teats of the animal with an thickened aqueous medium formulated to ensure a contact time between the teats and the medium of 15 seconds to 15 minutes, the medium comprising: (a) anionic surfactant of the formula RAO.sub.x.sup.-.sub.M.sup.+ wherein R is essentially organic, A is sulfur or phosphorus, x is 3 or 4, and M is topically acceptable cation; and (b) a pH modifying or maintaining substance in an amount sufficient to adjust a pH of the composition to a value in the range of 2.0 to 5.0.
Claim 2
Independent Claim 120 words
A method for killing mastitis-causing gram negative organisms including Pseudomonas aeruginosa, Escherichia coli, or Klebsiella pneumoniae or gram positive organisms including Staphylococcus auereus on an animal's teats comprising the step of treating the teats of the animal with an thickened aqueous medium formulated to ensure a contact time between the teats and the medium of 15 seconds to 15 minutes, the medium comprising: (a) anionic surfactant of the formula RAO.sub.x.sup.-.sub.M.sup.+ wherein R is essentially organic, A is sulfur or phosphorus, x is 3 or 4, and M is topically acceptable cation; and (b) a pH modifying or maintaining substance in an amount sufficient to adjust a pH of the composition to a value in the range of 2.0 to 5.0.
Claim 3
Dependent Claim 17 words
A method according to claim 1 wherein the R of the anionic surfactant is an alkyl-aryl radical.
Claim 4
Dependent Claim 17 words
A method according to claim 1 wherein the R of the anionic surfactant is linear alkyl-aryl radical.
Claim 5
Dependent Claim 16 words
A method according to claim 1 wherein R of the anionic surfactant is linear alkylbenzene radical.
Claim 6
Dependent Claim 14 words
A method according to claim 1 wherein A of the anionic surfactant is sulfur.
Claim 7
Dependent Claim 11 words
A method in accordance with claim 5 wherein x is 3.
Claim 8
Dependent Claim 13 words
A method in accordance with claim 5 wherein R is linear alkylbenzene radical.
Claim 9
Dependent Claim 16 words
A method in accordance with claim 7 wherein the anionic surfactant is sodium linear alkylbenzene sulfonate.
Claim 10
Dependent Claim 15 words
A method in accordance with claim 8 wherein the anionic surfactant is sodium dodecylbenzene sulfonate.
Claim 11
Dependent Claim 14 words
A method according to claim 1 wherein the anionic surfactant is lineaar alkylbenzene sulfonate.
Claim 12
Dependent Claim 14 words
A method according to claim 1 wherein the anionic surfactant is sodium dodecylbenzene sulfonate.
Claim 13
Dependent Claim 24 words
A method according to claim 1 wherein the pH modifying substance modifies the pH to a value in the range of 2.1 to 4.0.
Claim 14
Dependent Claim 24 words
A method according to claim 1 wherein the pH modifying substance modifies the pH of the composition in the range of 2.5 to 3.5.
Claim 15
Dependent Claim 15 words
A method according to claim 1 in which the pH modifying substance is a buffer.
Claim 16
Dependent Claim 19 words
A method according to claim 14 in which the buffer is a mixture of citric acid and sodium citrate.
Claim 17
Dependent Claim 11 words
A method according to claim 1 which further comprises a thixotrope.
Claim 18
Dependent Claim 13 words
A method according to claim 16 wherein the thixotrope is sodium carboxymethyl cellulose.
Claim 19
Independent Claim 124 words
A method for killing mastitis-causing gram negative organisms including Pseudomonas aeruginisa, Escherichia coli, or Klebsiella pneumoniae or gram positive organisms including Staphylococcus aureus on an animals's teats comprising the step of dipping the teats of the animal in a reservoir containing an thickened aqueous medium formulated to ensure a contact time between the teats and the medium of 15 seconds to 15 minutes, the medium comprising: (a) anionic surfactant of the formula RAO.sub.x.sup.- M.sup.+ wherein R is organic, x is 3 or 4, A is sulfur or phosphorus, and M is a topically acceptable cation; and (b) a pH modifying or maintaining substance in an amount sufficient to adjust the pH of the composition to a value in the range of 2.0 to 5.0.
Claim 20
Independent Claim 124 words
A method for killing mastitis-causing gram negative organisms including Pseudomonas aeruginisa, Escherichia coli, or Klebsiella pneumoniae or gram positive organisms including Staphylococcus aureus on an animals's teats comprising the step of dipping the teats of the animal in a reservoir containing an thickened aqueous medium formulated to ensure a contact time between the teats and the medium of 15 seconds to 15 minutes, the medium comprising: (a) anionic surfactant of the formula RAO.sub.x.sup.- M.sup.+ wherein R is organic, x is 3 or 4, A is sulfur or phosphorus, and M is a topically acceptable cation; and (b) a pH modifying or maintaining substance in an amount sufficient to adjust the pH of the composition to a value in the range of 2.0 to 5.0.
Claim 21
Dependent Claim 12 words
A method according to claim 18 wherein R is monovalent, alkyl-aryl radical.
Claim 22
Dependent Claim 12 words
A method according to claim 18 wherein R is an alkyl-benzene radical.
Claim 23
Dependent Claim 22 words
A method according to claim 18 wherein R is of the structure ##STR3## n having a value of from 9 to 18.
Claim 24
Dependent Claim 15 words
A method according to claim 21 wherein the C n H 2n-1 structure is linear.
Claim 25
Dependent Claim 14 words
A method according to claim 21 wherein the anionic surfactant is sodium dodecylbenzene sulfonate.
Claim 26
Dependent Claim 14 words
A method according to claim 18 wherein the pH maintaining substance is a buffer.
Claim 27
Dependent Claim 21 words
A method according to claim 24 wherein buffer modifies the composition to a pH in the range of 2.1 to 4.0.
Claim 28
Dependent Claim 22 words
A method according to claim 18 wherein the buffer maintains the pH of the medium in the range of 2.5 to 3.5.
Claim 29
Dependent Claim 17 words
A method according to claim 18 wherein the mastitis-causing organisms are killed in less than 5 minutes.
Claim 30
Dependent Claim 17 words
A method according to claim 18 wherein the mastitis-causing organisms are killed in less than 30 seconds.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1986-03-14 1986-09-13 1987-03-15 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1990-03-14 1990-09-13 1991-03-15 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1994-03-14 1994-09-13 1995-03-15 $7700.00 Window Closed / Lapsed

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