US4374980A
Expired / Lapsed
US
⏱️ 0.0 years remaining
3'-Deamino-3'-morpholino carminomycin
Assignee: Microbial Chemistry Research Foundation
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Filing: 1982-03-15
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Granted: 1983-02-22
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Expires: 2002-03-15
Abstract
Abstract Disclosed is 3'-deamino-3'-morpholino-carminomycin, a new anthracycline glycoside having both antimicrobial and antitumor activity. Also disclosed is a new N-alkylation procedure for preparing the above compound as well as the known anthracyclines, 3'-deamino-3'-morpholino-adriamycin and 3'-deamino-3'-morpholino-daunomycin, in high yield.
Inventors
- 👤 Hamao Umezawa
- 👤 Tomio Takeuchi
- 👤 Kuniaki Tatsuta
- 👤 Yoshikazu Takahashi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 00:32
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/20; C07H15/24; C07H15/252; A; A61; A61P; A61P31/00; A61P31/04; A61P35/00
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
16 words
The anthracycline glycoside 3'-deamino-3'-morpholino-carminomycin of the formula ##STR17## or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim
16 words
The anthracycline glycoside 3'-deamino-3'-morpholino-carminomycin of the formula ##STR17## or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
82 words
A process for preparing an anthracycline glycoside of the formula ##STR18## wherein R 1 represents H of CH 3 and R 2 represents H or OH, provided that when R 1 is H, R 2 is H, or an acid addition salt thereof, which process comprises reacting a compound of the formula ##STR19## wherein R 1 and R 2 are as defined above, or an acid addition salt thereof, with a compound of the formula ##STR20## wherein X represents Br or I.
Claim 4
Dependent Claim
82 words
A process for preparing an anthracycline glycoside of the formula ##STR18## wherein R 1 represents H of CH 3 and R 2 represents H or OH, provided that when R 1 is H, R 2 is H, or an acid addition salt thereof, which process comprises reacting a compound of the formula ##STR19## wherein R 1 and R 2 are as defined above, or an acid addition salt thereof, with a compound of the formula ##STR20## wherein X represents Br or I.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-02-21 | 1986-08-23 | 1987-02-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-02-21 | 1990-08-23 | 1991-02-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-02-21 | 1994-08-23 | 1995-02-22 | $7700.00 | Window Closed / Lapsed |