US4373094A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Anthracycline derivatives
Assignee: Sanraku Inc
•
Filing: 1981-07-29
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Granted: 1983-02-08
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Expires: 2001-07-29
Abstract
Abstract New anthracycline compounds, 2-hydroxy-aclacinomycins M, N, S and T having potent antitumor activity and low toxicity, and the processes for the preparation thereof from 2-hydroxy-aclacinomycin A by reduction or acid hydrolysis are disclosed.
Inventors
- 👤 Toshikazu Oki
- 👤 Yasue Matsuzawa
- 👤 Tomoyuki Ishikura
- 👤 Tomio Takeuchi
- 👤 Hamao Umezawa
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 12:45
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/20; C07H15/24; C07H15/252; A; A61; A61P; A61P35/00; C12; C12N; C12N1/00; C12N1/20; C12N1/205; C12P; C12P19/00; C12P19/44; C12P19/56; C12R; C12R2001/00; C12R2001/01; C12R2001/465
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
27 words
Anthracycline derivatives and acid addition salts thereof having the general formula: ##STR9## wherein R represents a hydrogen atom, or a sugar chain moiety of the formula: ##STR10##
Claim 2
Dependent Claim
27 words
Anthracycline derivatives and acid addition salts thereof having the general formula: ##STR9## wherein R represents a hydrogen atom, or a sugar chain moiety of the formula: ##STR10##
Claim 3
Dependent Claim
31 words
Anthracycline derivatives and acid addition salts thereof according to claim 1 in which the compound is 2-hydroxy-aclacinomycin N of the formula I wherein R represents a group of the formula: ##STR11##
Claim 4
Dependent Claim
28 words
Anthracycline derivatives and acid addition salts thereof in which the compound is 2-hydroxy-aclacinomycin M having the general formula: ##STR12## wherein R represents a group of the formula: ##STR13##
Claim 5
Dependent Claim
28 words
Anthracycline derivatives and acid addition salts thereof in which the compound is 2-hydroxy-aclacinomycin M having the general formula: ##STR12## wherein R represents a group of the formula: ##STR13##
Claim 6
Dependent Claim
28 words
Anthracycline derivatives and acid addition salts thereof in which the compound is 2-hydroxy-aclacinomycin S having the general formula: ##STR14## wherein R represents a group of the formula: ##STR15##
Claim 7
Dependent Claim
28 words
Anthracycline derivatives and acid addition salts thereof in which the compound is 2-hydroxy-aclacinomycin S having the general formula: ##STR14## wherein R represents a group of the formula: ##STR15##
Claim 8
Dependent Claim
25 words
Anthracycline derivatives and acid addition salts thereof in which the compound is 2-hydroxy-aclacinomycin T having the general formula: ##STR16## wherein R represents a hydrogen atom.
Claim 9
Dependent Claim
25 words
Anthracycline derivatives and acid addition salts thereof in which the compound is 2-hydroxy-aclacinomycin T having the general formula: ##STR16## wherein R represents a hydrogen atom.
References Cited (Backward Citations)
US4127714A
Cited
US4316011A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-02-07 | 1986-08-09 | 1987-02-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-02-07 | 1990-08-09 | 1991-02-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-02-07 | 1994-08-09 | 1995-02-08 | $7700.00 | Window Closed / Lapsed |