US4127714A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Anthracycline glycosides
Assignee: Microbial Chemistry Research Foundation
•
Filing: 1977-08-09
•
Granted: 1978-11-28
•
Expires: 1997-08-09
Abstract
Abstract New antitumor agents designated rhodirubin A and B, which are anthracycline glycosides and inhibit the growth of gram-positive bacteria and mammalian tumors, are produced by fermentation of rhodirubin-producing strains of Streptomyces, e.g. Streptomyces sp. ME 505-HEI (ATCC 31273).
Inventors
- 👤 Hamao Umezawa
- 👤 Tomio Takeuchi
- 👤 Masa Hamada
- 👤 Masaaki Ishizuka
- 👤 Hiroshi Naganawa
- 👤 Toshikazu Oki
- 👤 Taiji Inui
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 21:57
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/20; C07H15/24; C07H15/252; A; A61; A61P; A61P31/00; A61P31/04; A61P35/00; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/822; Y10S435/886
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
23 words
An anthracycline glycoside of the general formula ##STR4## wherein R represents ##STR5## or a non-toxic acid addition salt or deoxyribonucleic acid complex thereof.
Claim 2
Dependent Claim
23 words
An anthracycline glycoside of the general formula ##STR4## wherein R represents ##STR5## or a non-toxic acid addition salt or deoxyribonucleic acid complex thereof.
Claim 3
Dependent Claim
20 words
The anthracycline glycoside rhodirubin A of the formula ##STR6## or a non-toxic acid addition salt or deoxyribonucleic acid complex thereof.
Claim 4
Dependent Claim
20 words
The anthracycline glycoside rhodirubin A of the formula ##STR6## or a non-toxic acid addition salt or deoxyribonucleic acid complex thereof.
Claim 5
Dependent Claim
16 words
The anthracycline glycoside rhodirubin A of the formula ##STR7## or a non-toxic acid addition salt thereof.
Claim 6
Dependent Claim
16 words
The anthracycline glycoside rhodirubin A of the formula ##STR7## or a non-toxic acid addition salt thereof.
Claim 7
Dependent Claim
10 words
The hydrochloride salt of the anthracycline glycoside of claim 3.
Claim 8
Dependent Claim
20 words
The anthracycline glycoside rhodirubin B of the formula ##STR8## or a non-toxic acid addition salt or deoxyribonucleic acid complex thereof.
Claim 9
Dependent Claim
20 words
The anthracycline glycoside rhodirubin B of the formula ##STR8## or a non-toxic acid addition salt or deoxyribonucleic acid complex thereof.
Claim 10
Dependent Claim
16 words
The anthracycline glycoside rhodirubin B of the formula ##STR9## or a non-toxic acid addition salt thereof.
Claim 11
Dependent Claim
16 words
The anthracycline glycoside rhodirubin B of the formula ##STR9## or a non-toxic acid addition salt thereof.
Claim 12
Dependent Claim
10 words
The hydrochloride salt of the anthracycline glycoside of claim 6.
References Cited (Backward Citations)
US3988315A
Cited
US4039736A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-11-27 | 1982-05-29 | 1982-11-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-11-27 | 1986-05-29 | 1986-11-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-11-27 | 1990-05-29 | 1990-11-28 | $7700.00 | Window Closed / Lapsed |