US4363759A
Expired / Lapsed
US
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Chemiluminescent-labeled haptens and antigens
Assignee: Bayer Corp
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Filing: 1978-07-24
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Granted: 1982-12-14
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Expires: 1998-07-24
Abstract
Abstract Chemiluminescent-labeled conjugates of the formula: ##STR1## wherein one of R 1 and R 2 is hydrogen and the other is -NR 3 R 4 ; R 3 is hydrogen or straight chain alkyl containing 1-4 carbon atoms and R 4 is ##STR2## wherein n=1-3 and L(CO-- is the ligand or analog bound through an amide bond. Intermediates produced in the synthesis of such conjugates are also disclosed.
Inventors
- 👤 Robert C. Boguslaski
- 👤 Robert J. Carrico
- 👤 James E. Christner
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 06:52
CPC Classifications
C; C07; C07D; C07D209/00; C07D209/02; C07D209/44; C07D209/48; C07D237/00; C07D237/26; C07D237/30; C07D237/32; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/531; G01N33/532; G01N33/533; G01N33/58; G01N33/582; Y; Y10; Y10S; Y10S530/00; Y10S530/802
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
11 words
An insulin-chemiluminescent substance conjugate having luminescent activity measurable by photosensitive means.
Claim 2
Dependent Claim
11 words
An insulin-chemiluminescent substance conjugate having luminescent activity measurable by photosensitive means.
Claim 3
Dependent Claim
32 words
The insulin-chemiluminescent conjugate of claim 1 wherein said chemiluminescent substance is selected from the group consisting of 2,3-dihydrophthalazine-1,4-diones of the following general formula: ##STR50## where R is NH 2 , and luciferin.
Claim 4
Dependent Claim
12 words
The insulin-chemiluminescent conjugate of claim 1 wherein said chemiluminescent substance is luminol.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-12-13 | 1986-06-14 | 1986-12-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-12-13 | 1990-06-14 | 1990-12-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-12-13 | 1994-06-14 | 1994-12-14 | $7700.00 | Window Closed / Lapsed |