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US4055644A Expired / Lapsed US ⏱️ 0.0 years remaining

Hydroxyalkyl substituted-4,5-dihydropyridazin(2H)-3-ones

Assignee: Sandoz Inc
•
Filing: 1975-09-18
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Granted: 1977-10-25
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Expires: 1995-09-18
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Abstract

Abstract Hydroxyalkyl and aryl or heterocyclic substituted-4,5-dihydropyridazin(2H)-3-ones and diazobicyclo-ene-ones, e.g., 6-(p-chlorophenyl)-2-(2-hydroxybutyl)-4,5-dihydropyridazin(2H)-3-one are prepared by condensing 1-hydrazino-2-alkanols with aryl or heterocyclic- gamma -keto acids and are useful as central nervous system depressants.

Inventors

  • 👤 William J. Houlihan

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 13:12
CPC Classifications
C; C07; C07D; C07D237/00; C07D237/26; C07D237/02; C07D237/04; C07D237/30; C07D237/32

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 44 words
A compound of the formula ##STR9## where R is lower alkyl having 1 or 4 carbon atoms, R 1 , r 2 , r 3 and R 4 each independently represent hydrogen or lower alkyl having 1 to 4 carbon atoms, and represents ##STR10##
Claim 2
Dependent Claim 44 words
A compound of the formula ##STR9## where R is lower alkyl having 1 or 4 carbon atoms, R 1 , r 2 , r 3 and R 4 each independently represent hydrogen or lower alkyl having 1 to 4 carbon atoms, and represents ##STR10##
Claim 3
Dependent Claim 8 words
The compound of claim 1 which is 2-(2-hydroxybutyl)-6-(2-thienyl)-4,5-dihydropyridazin(2H)-3-one.
Claim 4
Dependent Claim 8 words
The compound of claim 1 which is 6-(2-thienyl)-2-(2-hydroxypropyl)-4,5-dihydropyridazin(2H)-3-one.
Claim 5
Dependent Claim 8 words
The compound of claim 1 which is 6-(2-thienyl)-2-(2-hydroxyhexyl)-4,5-dihydropyridazin(2H)-3-one.

References Cited (Backward Citations)

JPS442991Y1 Cited
US3586681A Cited
US3931176A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1980-10-24 1981-04-25 1981-10-25 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1984-10-24 1985-04-25 1985-10-25 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1988-10-24 1989-04-25 1989-10-25 $7700.00 Window Closed / Lapsed

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