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US4055644A
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Hydroxyalkyl substituted-4,5-dihydropyridazin(2H)-3-ones
Assignee: Sandoz Inc
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Filing: 1975-09-18
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Granted: 1977-10-25
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Expires: 1995-09-18
Abstract
Abstract Hydroxyalkyl and aryl or heterocyclic substituted-4,5-dihydropyridazin(2H)-3-ones and diazobicyclo-ene-ones, e.g., 6-(p-chlorophenyl)-2-(2-hydroxybutyl)-4,5-dihydropyridazin(2H)-3-one are prepared by condensing 1-hydrazino-2-alkanols with aryl or heterocyclic- gamma -keto acids and are useful as central nervous system depressants.
Inventors
- 👤 William J. Houlihan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 20:41
CPC Classifications
C; C07; C07D; C07D237/00; C07D237/26; C07D237/02; C07D237/04; C07D237/30; C07D237/32
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
44 words
A compound of the formula ##STR9## where R is lower alkyl having 1 or 4 carbon atoms, R 1 , r 2 , r 3 and R 4 each independently represent hydrogen or lower alkyl having 1 to 4 carbon atoms, and represents ##STR10##
Claim 2
Dependent Claim
44 words
A compound of the formula ##STR9## where R is lower alkyl having 1 or 4 carbon atoms, R 1 , r 2 , r 3 and R 4 each independently represent hydrogen or lower alkyl having 1 to 4 carbon atoms, and represents ##STR10##
Claim 3
Dependent Claim
8 words
The compound of claim 1 which is 2-(2-hydroxybutyl)-6-(2-thienyl)-4,5-dihydropyridazin(2H)-3-one.
Claim 4
Dependent Claim
8 words
The compound of claim 1 which is 6-(2-thienyl)-2-(2-hydroxypropyl)-4,5-dihydropyridazin(2H)-3-one.
Claim 5
Dependent Claim
8 words
The compound of claim 1 which is 6-(2-thienyl)-2-(2-hydroxyhexyl)-4,5-dihydropyridazin(2H)-3-one.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-10-24 | 1981-04-25 | 1981-10-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-10-24 | 1985-04-25 | 1985-10-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-10-24 | 1989-04-25 | 1989-10-25 | $7700.00 | Window Closed / Lapsed |