Patent US4362745A successfully refreshed from Google Patents.
US4362745A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Medical process and preparation
Assignee: Individual
•
Filing: 1981-11-23
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Granted: 1982-12-07
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Expires: 2001-11-23
Abstract
Abstract A medication and method of treatment for reducing tissue trauma in an animal, comprising the use of a N,N-dimethyl aspartic acid and/or N,N-dimethyl glutamic acid, physiologically acceptable salt or salts of either of the foregoing, and/or a mixture or mixtures of the foregoing, in which a suitable maskant such as benzyl alcohol may be included, the preferable method of treatment being a topical application to the skin to achieve penetration into the areas of tissue trauma.
Inventors
- 👤 Frederick B. Johnston
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 05:18
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/185; A61K31/19; A61K31/195; A61P; A61P29/00
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
60 words
A method of reducing tissue trauma, neuro-muscular spasms, and musculo-skeletal disorders in an animal, by administering to said animal an effective amount of a compound which comprises one or more N-monoalkyl and/or N-N, dialkyl derivatives of the following amino acids: aspartic acid; glutamic acid; hydroxyglutamic acid; alpha amino adipic acid; serine; threonine; physiologically acceptable salt or salts of the above.
Claim 2
Independent Claim
60 words
A method of reducing tissue trauma, neuro-muscular spasms, and musculo-skeletal disorders in an animal, by administering to said animal an effective amount of a compound which comprises one or more N-monoalkyl and/or N-N, dialkyl derivatives of the following amino acids: aspartic acid; glutamic acid; hydroxyglutamic acid; alpha amino adipic acid; serine; threonine; physiologically acceptable salt or salts of the above.
Claim 3
Dependent Claim
14 words
The method of claim 1 wherein said N-monoalkyl and/or N-N dialkyl derivatives comprises methyl.
Claim 4
Dependent Claim
14 words
The method of claim 1, wherein said N-monoalkyl and/or N-N dialkyl derivatives comprise ethyl.
Claim 5
Dependent Claim
14 words
The method of claim 1, wherein said N-monoalkyl and/or N-N dialkyl derivatives comprise propyl.
Claim 6
Dependent Claim
14 words
The method of claim 1, wherein said N-monoalkyl and/or N-N dialkyl derivatives comprise butyl.
Claim 7
Dependent Claim
14 words
The method of claim 1, wherein said N-monoalkyl and/or N-N dialkyl derivatives comprise amyl.
Claim 8
Dependent Claim
26 words
A method of claim 1 in which said medication of claim 1 has a pH in the range from about 5 to and including about 7.
Claim 9
Dependent Claim
28 words
A method of claim 1 in which said medication has an effective proportion of maskant for any objectionable amine aroma which may otherwise be noticeable in said medication.
Claim 10
Dependent Claim
74 words
A process for producing a medication and product for the reduction of tissue trauma, neuro-muscular spasms, musculoskeletal disorders in an animal, and/or a potentiator of bio-chemical activity in a biological entity having the characteristics of oil and water miscibility and solubility, and chelation-sequestration to enhance penetration and absorption comprising: (1) refluxing an aqueous solution of one or more amino acids with formaldehyde (formalin) and formic acid; (2) aspiration of excess formaldehyde and formic acid.
Claim 11
Dependent Claim
74 words
A process for producing a medication and product for the reduction of tissue trauma, neuro-muscular spasms, musculoskeletal disorders in an animal, and/or a potentiator of bio-chemical activity in a biological entity having the characteristics of oil and water miscibility and solubility, and chelation-sequestration to enhance penetration and absorption comprising: (1) refluxing an aqueous solution of one or more amino acids with formaldehyde (formalin) and formic acid; (2) aspiration of excess formaldehyde and formic acid.
Claim 12
Dependent Claim
15 words
The process of claim 9 wherein said refluxing is at 100° C. to 110° C.
Claim 13
Dependent Claim
15 words
The process as in claim 10 wherein said refluxing is under a slightly reduced pressure.
Claim 14
Dependent Claim
16 words
The process as in claim 9 wherein said resultant mixture is neutralized to preferably pH 6.0.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-12-06 | 1986-06-07 | 1986-12-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-12-06 | 1990-06-07 | 1990-12-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-12-06 | 1994-06-07 | 1994-12-07 | $7700.00 | Window Closed / Lapsed |