US4362697A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Homogeneous specific binding assay test device having copolymer enhancing substance
Assignee: Bayer Corp
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Filing: 1981-04-20
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Granted: 1982-12-07
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Expires: 2001-04-20
Abstract
Abstract A test device for performing homogeneous specific binding assays is composed of a carrier matrix having incorporated therein reagents and an enhancer substance. The enhancer substance is a copolymer of vinyl pyrrolidone and a type of acrylic comonomer.
Inventors
- 👤 David L. Tabb
- 👤 Richard J. Tyhach
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 12:35
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/536; G01N33/542; Y; Y10; Y10S; Y10S435/00; Y10S435/805
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
104 words
A test device for determining the presence of a ligand in, or the ligand binding capacity of a liquid sample, comprising (a) reagents for a homogeneous specific binding assay system capable of producing a detectable response which is a function of the presence of the ligand in or the ligand binding capacity of the sample; (b) an enhancer substance comprising a quaternized copolymer of vinylpyrrolidone and a comonomer having the structure ##STR3## in which R, same or different, is lower alkyl, R' is H or lower alkyl and R" is lower alkylene; and (c) a carrier matrix incorporated with said reagents and enhancer substance.
Claim 2
Dependent Claim
104 words
A test device for determining the presence of a ligand in, or the ligand binding capacity of a liquid sample, comprising (a) reagents for a homogeneous specific binding assay system capable of producing a detectable response which is a function of the presence of the ligand in or the ligand binding capacity of the sample; (b) an enhancer substance comprising a quaternized copolymer of vinylpyrrolidone and a comonomer having the structure ##STR3## in which R, same or different, is lower alkyl, R' is H or lower alkyl and R" is lower alkylene; and (c) a carrier matrix incorporated with said reagents and enhancer substance.
Claim 3
Dependent Claim
11 words
The test device of claim 1 in which R is methyl.
Claim 4
Dependent Claim
11 words
The test device of claim 1 in which R' is H.
Claim 5
Dependent Claim
15 words
The test device of claim 1 in which R" is --CH 2 --CH 2 --.
Claim 6
Dependent Claim
13 words
The test device of claim 1 in which said comonomer is dimethylaminoethyl methacrylate.
References Cited (Backward Citations)
US4168146A
Cited
US4055394A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-12-06 | 1986-06-07 | 1986-12-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-12-06 | 1990-06-07 | 1990-12-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-12-06 | 1994-06-07 | 1994-12-07 | $7700.00 | Window Closed / Lapsed |