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US4361483A Expired / Lapsed US ⏱️ 0.0 years remaining

Disposable pharmaceutical filter assembly

Assignee: Pall Corp
•
Filing: 1981-11-02
•
Granted: 1982-11-30
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Expires: 2001-11-02
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Abstract

Abstract A disposable unitary filter assembly is provided for filtering pharmaceutical and other fluid materials without danger of contaminating downstream effluent in the event of leakage of unfiltered fluid material past a filter seal, comprising, in combination, a filter housing of plastic material comprising first and second housing parts; the first housing part having a first fluid chamber open at one side, a fluid port opening into the fluid chamber, and a peripheral sealing surface extending in at least two planes at an angle to each other of from 30° to 150°; the second housing part having a second fluid chamber open at one side, a fluid port opening into the fluid chamber and a peripheral sealing surface extending in at least two planes at an angle to each other of from 30° to 150°; a filter element disposed in the second fluid chamber in the second housing part and comprising a tubular filter confined between and sealed in a fluid-tight seal to end caps at each end thereof, of which a first end cap is closed, and a second end cap is of plastic material and has an opening therethrough communicating the interior of the tubular filter with the first fluid chamber, and a peripheral lip extending into sealing engagement with and between the peripheral sealing surface of each housing part in each plane thereof and permanently bonded thereto; the peripheral lip extending across and sealingly closing off the open sides of the first and second fluid chambers, so that fluid communication therebetween is restricted to the opening in the second end cap via the filter, and the leakage path at the end cap peripheral lip does not bypass the filter, but runs to the exterior of the housing between the lip and one housing part.

Inventors

  • 👤 David B. Pall

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 21:46
CPC Classifications
B; B01; B01D; B01D36/00; B01D36/001; B01D27/00; B01D27/005; B01D27/08

Claims Analysis

Total Claims: 21
Claim 1
Independent Claim 299 words
A disposable unitary filter assembly free from internal seals for filtering pharmaceutical fluid materials without danger of microorganism contamination of downstream filter effluent in the event of leakage of unfiltered fluid material past a filter seal, comprising, in combination, a filter housing of plastic material comprising first and second housing parts; the first housing part having a first fluid chamber open at one side, a fluid port opening into the fluid chamber, and a peripheral sealing surface extending in at least two planes at an angle to each other of from 30° to 150°; the second housing part having a second fluid chamber open at one side, a fluid port opening into the fluid chamber and a peripheral sealing surface extending in at least two planes at an angle to each other of from 30° to 150°; a filter element disposed in the second fluid chamber in the second housing part and comprising a tubular filter confined between and sealed in a fluid-tight seal to end caps at each end thereof, of which a first end cap is closed, and a second end cap is of plastic material and has an opening therethrough communicating the interior of the tubular filter with the first fluid chamber, and a peripheral lip extending into sealing engagement with and between the peripheral sealing surface of each housing part in each plane thereof and permanently bonded thereto; the peripheral lip extending across and sealingly closing off the open sides of the first and second fluid chambers, so that fluid communication therebetween is restricted to the opening in the second end cap via the filter, and the leakage path at the end cap peripheral lip does not bypass the filter, but runs to the exterior of the housing between the lip and one housing part.
Claim 2
Dependent Claim 299 words
A disposable unitary filter assembly free from internal seals for filtering pharmaceutical fluid materials without danger of microorganism contamination of downstream filter effluent in the event of leakage of unfiltered fluid material past a filter seal, comprising, in combination, a filter housing of plastic material comprising first and second housing parts; the first housing part having a first fluid chamber open at one side, a fluid port opening into the fluid chamber, and a peripheral sealing surface extending in at least two planes at an angle to each other of from 30° to 150°; the second housing part having a second fluid chamber open at one side, a fluid port opening into the fluid chamber and a peripheral sealing surface extending in at least two planes at an angle to each other of from 30° to 150°; a filter element disposed in the second fluid chamber in the second housing part and comprising a tubular filter confined between and sealed in a fluid-tight seal to end caps at each end thereof, of which a first end cap is closed, and a second end cap is of plastic material and has an opening therethrough communicating the interior of the tubular filter with the first fluid chamber, and a peripheral lip extending into sealing engagement with and between the peripheral sealing surface of each housing part in each plane thereof and permanently bonded thereto; the peripheral lip extending across and sealingly closing off the open sides of the first and second fluid chambers, so that fluid communication therebetween is restricted to the opening in the second end cap via the filter, and the leakage path at the end cap peripheral lip does not bypass the filter, but runs to the exterior of the housing between the lip and one housing part.
Claim 3
Dependent Claim 25 words
A filter assembly in accordance with claim 1, in which the housing parts and filter end cap lip are integrated together in a leak-tight seal.
Claim 4
Dependent Claim 24 words
A filter assembly in accordance with claim 2, in which the housing parts and filter end cap lip are of the same plastic material.
Claim 5
Dependent Claim 15 words
A filter assembly in accordance with claim 3, in which the plastic material is polypropylene.
Claim 6
Dependent Claim 28 words
A filter assembly in accordance with claim 1, in which the second housing part is provided with a vent opening into an upper portion of the second chamber.
Claim 7
Dependent Claim 28 words
A filter assembly in accordance with claim 1, in which the second housing part is provided with a drain opening into a lower portion of the second chamber.
Claim 8
Dependent Claim 24 words
A filter assembly in accordance with claim 1, in which the peripheral sealing surfaces are at an angle of about 90° to each other.
Claim 9
Dependent Claim 18 words
A filter assembly in accordance with claim 1, in which the housing parts are formed of molded plastic.
Claim 10
Dependent Claim 16 words
A filter assembly in accordance with claim 1, in which the filter is a plastic membrane.
Claim 11
Dependent Claim 22 words
A filter assembly in accordance with claim 1, in which the filter has a pore size of less than 0.3 micron absolute.
Claim 12
Dependent Claim 18 words
A filter assembly in accordance with claim 1, in which the filter is supported on an internal core.
Claim 13
Dependent Claim 39 words
A filter assembly in accordance with claim 1, in which the filter comprises a multiplicity of filters of differing pore size, arranged in the order of decreasing pore size in the direction of fluid flow through the filter element.
Claim 14
Dependent Claim 18 words
A filter assembly in accordance with claim 1, in which the filter is supported with an external sheath.
Claim 15
Dependent Claim 52 words
A filter assembly in accordance with claim 1, in which the peripheral lip on the second end cap extends between the housing parts in a manner to prevent a seal between the lip and at least one housing part, so as to maintain a leakage path to the exterior of the housing.
Claim 16
Dependent Claim 201 words
A filter assembly in accordance with claim 1, in which one of the housing parts has a connector for joining the housing part to a fluid line that protects sealing means for the connector from contact with fluid passing through the housing and the connector, comprising, a first connector having a fluid passage therethrough and attached to and extending outwardly from the filter housing part and having side surfaces adapted for attachment to lapped side surfaces of a second connector for a fluid line; a second connector having a fluid passage therethrough and removably attached to the first connector and concentric therewith in a manner such that one connector is within the other and side surfaces thereof extend along side surfaces of the first connector; sealing means disposed between and sealing the juxtaposed side surfaces of the first and second connectors in a fluid-tight seal; the outer connector extending beyond the inner connector and having an inwardly tapering fluid passage wall having a lesser diameter than the outside diameter of the inner connector and engaging the end of the inner connector in a fluid-tight seal, preventing entry of fluid between the connectors and thereby preventing fluid from reaching the sealing means.
Claim 17
Dependent Claim 202 words
A connector for attaching a filter housing to a fluid line that protects sealing means for the connector from contact with fluid passing through the housing and the connector, comprising, in combination, a filter housing having a fluid chamber, a fluid port opening into the fluid chamber, and a first connector having a fluid passage therethrough and attached to and extending outwardly from the filter housing, and having side surfaces adapted for attachment to lapped side surfaces of a second connector for a fluid line; a second connector having a fluid passage therethrough and removably attached to the first connector and concentric therewith in a manner such that one connector is within the other and side surfaces thereof extend along side surfaces of the first connector; sealing means disposed between and sealing the juxtaposed side surfaces of the first and second connectors in a fluid-tight seal; the outer connector extending beyond the inner connector and having an inwardly tapering fluid passage wall having a lesser diameter than the outside diameter of the inner connector and engaging the end of the inner connector in a fluid-tight seal, preventing entry of fluid between the connectors and thereby preventing fluid from reaching the sealing means.
Claim 18
Dependent Claim 202 words
A connector for attaching a filter housing to a fluid line that protects sealing means for the connector from contact with fluid passing through the housing and the connector, comprising, in combination, a filter housing having a fluid chamber, a fluid port opening into the fluid chamber, and a first connector having a fluid passage therethrough and attached to and extending outwardly from the filter housing, and having side surfaces adapted for attachment to lapped side surfaces of a second connector for a fluid line; a second connector having a fluid passage therethrough and removably attached to the first connector and concentric therewith in a manner such that one connector is within the other and side surfaces thereof extend along side surfaces of the first connector; sealing means disposed between and sealing the juxtaposed side surfaces of the first and second connectors in a fluid-tight seal; the outer connector extending beyond the inner connector and having an inwardly tapering fluid passage wall having a lesser diameter than the outside diameter of the inner connector and engaging the end of the inner connector in a fluid-tight seal, preventing entry of fluid between the connectors and thereby preventing fluid from reaching the sealing means.
Claim 19
Dependent Claim 23 words
A filter assembly in accordance with claim 16, in which the first and second connectors are threadably attached together in a leak-tight seal.
Claim 20
Dependent Claim 17 words
A filter assembly in accordance with claim 16, in which the sealing means is an O-ring seal.
Claim 21
Dependent Claim 20 words
A filter assembly in accordance with claim 16, in which the first connector is concentrically disposed within the second connector.

References Cited (Backward Citations)

US2554748A Cited
US2931507A Cited
US3386585A Cited
US3856683A Cited
US3794180A Cited
US3935111A Cited
US4126558A Cited
US4148732A Cited
US4126554A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1985-11-29 1986-05-31 1986-11-30 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1989-11-29 1990-05-31 1990-11-30 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1993-11-29 1994-05-31 1994-11-30 $7700.00 Window Closed / Lapsed

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