Patent US4352821A successfully refreshed from Google Patents.
US4352821A
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Sweet tableting agent
Assignee: Yamanouchi Consumer Inc
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Filing: 1981-07-21
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Granted: 1982-10-05
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Expires: 2001-07-21
Abstract
Abstract A composition, useful as a sweet tableting agent in tablet formulations, comprises a compressible granule. The compressible granule is formed from fructose and a carrier for the fructose. The carrier is preferably an edible, substantially water insoluble inorganic salt. A preferred compressible granule has about 20 to about 55 wt. % fructose and a moisture content of less than about 2 wt. %.
Inventors
- 👤 Mark A. Doran
- 👤 Thomas R. Rumolo
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 20:40
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/2004; A61K9/2009
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
54 words
A composition consisting essentially of: fructose and a substantially water insoluble carrier for the fructose, the fructose and the carrier together forming a compressible granule, the fructose being in a weight ratio with respect to the carrier of from about 0.1:1 to about 2.3:1, the carrier for the fructose being an edible, inorganic salt.
Claim 2
Dependent Claim
54 words
A composition consisting essentially of: fructose and a substantially water insoluble carrier for the fructose, the fructose and the carrier together forming a compressible granule, the fructose being in a weight ratio with respect to the carrier of from about 0.1:1 to about 2.3:1, the carrier for the fructose being an edible, inorganic salt.
Claim 3
Dependent Claim
22 words
The composition as in claim 1 wherein: the compressible granule includes a plurality of carrier particles disposed in a matrix of fructose.
Claim 4
Dependent Claim
21 words
The composition as in claim 1 wherein: the granule has a moisture content of not greater than about 2 wt. %.
Claim 5
Dependent Claim
29 words
The composition as in claim 1 wherein: the carrier for the fructose is selected from the group consisting of tricalcium phosphate, dicalcium phosphate anhydrous, magnesium carbonate and mixtures thereof.
Claim 6
Dependent Claim
22 words
The composition as in claim 2 wherein: the compressible granule has a particle size of about 100 microns to about 200 microns.
Claim 7
Dependent Claim
23 words
The composition as in claim 5 wherein: the fructose is about 20 wt. % to about 55 wt. % of the compressible granule.
Claim 8
Dependent Claim
66 words
A sweet tableting agent comprising: a plurality of compressible granules having a particle size of from about 50 to about 300 microns, the granules derived from an agglutination between fructose and an edible, substantially water insoluble inorganic salt, an average one granule having a moisture content of not greater than about 2 wt. % and consisting essentially of fructose and the edible, substantially water insoluble salt.
Claim 9
Dependent Claim
66 words
A sweet tableting agent comprising: a plurality of compressible granules having a particle size of from about 50 to about 300 microns, the granules derived from an agglutination between fructose and an edible, substantially water insoluble inorganic salt, an average one granule having a moisture content of not greater than about 2 wt. % and consisting essentially of fructose and the edible, substantially water insoluble salt.
Claim 10
Dependent Claim
32 words
The sweet tableting agent as in claim 7 wherein: the fructose is from about 20 to about 55 wt. % with respect to the average one granule of the plurality of granules.
Claim 11
Dependent Claim
33 words
The sweet tableting agent as in claim 7 wherein: the edible, substantially water insoluble inorganic salt is selected from the group consisting of tricalcium phosphate, dicalcium phosphate anhydrous, magnesium carbonate, and mixtures thereof.
Claim 12
Dependent Claim
72 words
A sweet tableting agent formed by the steps comprising: forming a substantially dry fluidized bed of a substantially water insoluble inorganic salt; spraying a solution containing from about 20 to about 80 wt. % of fructose onto the fluidized bed of substantially dry water insoluble inorganic salt to form granules; and drying the granules to a moisture content of not greater than about 2 wt. %, the dried granules being directly compressible.
Claim 13
Dependent Claim
72 words
A sweet tableting agent formed by the steps comprising: forming a substantially dry fluidized bed of a substantially water insoluble inorganic salt; spraying a solution containing from about 20 to about 80 wt. % of fructose onto the fluidized bed of substantially dry water insoluble inorganic salt to form granules; and drying the granules to a moisture content of not greater than about 2 wt. %, the dried granules being directly compressible.
Claim 14
Dependent Claim
44 words
The composition as in claim 10 wherein: the inorganic salt of the fluidized bed has an particle size of from about 3 to about 50 microns and is selected from the group consisting of tricalcium phosphate, anhydrous calcium phosphate, magnesium carbonate, and mixtures thereof.
Claim 15
Dependent Claim
15 words
The composition as in claim 10 wherein: the fructose solution is sprayed as atomized droplets.
Claim 16
Dependent Claim
19 words
The sweet tableting agent as in claim 10 wherein: the dried granules consist essentially of fructose and inorganic salt.
Claim 17
Dependent Claim
18 words
The sweet tableting agent as in claim 13 wherein: the fructose of the dried granules is crystallized thereon.
Claim 18
Dependent Claim
19 words
The sweet tableting agent as in claim 7 wherein: the fructose of the average one granule is adsorbed thereon.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-10-04 | 1986-04-05 | 1986-10-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-10-04 | 1990-04-05 | 1990-10-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-10-04 | 1994-04-05 | 1994-10-05 | $7700.00 | Window Closed / Lapsed |