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US4351835A Expired / Lapsed US ⏱️ 0.0 years remaining

Method for preventing body fat deposition in mammals

Assignee: Montefiore Medical Center
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Filing: 1981-04-01
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Granted: 1982-09-28
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Expires: 2001-04-01
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Abstract

Abstract A method for reducing the rate of liver triglyceride synthesis and body fat deposition in mammals by orally administering over a prolonged period a therapeutic mixture of effective amounts of pyruvate and dihydroxyacetone to which may be added riboflavin. The method also has the effect of increasing the glycogen-storing capabilities of the liver.

Inventors

  • 👤 Ronald T. Stanko

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-02 11:59
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/185; A61K31/19; A61K31/33; A61K31/395; A61K31/495; A61K31/505; A61K31/519; A61K31/525; A61P; A61P1/00; A61P1/16; A61P3/00; A61P3/04; A61P3/06; A61P3/08

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 42 words
A method for controlling weight in a mammal, which comprises administering orally to said mammal a therapeutic mixture of pyruvate and dihydroxyacetone in an effective amount to induce a weight loss or to reduce an expected weight gain from a given diet.
Claim 2
Independent Claim 42 words
A method for controlling weight in a mammal, which comprises administering orally to said mammal a therapeutic mixture of pyruvate and dihydroxyacetone in an effective amount to induce a weight loss or to reduce an expected weight gain from a given diet.
Claim 3
Dependent Claim 12 words
The method of claim 1 in which said mixture also includes riboflavin.
Claim 4
Dependent Claim 15 words
The method of claim 1 wherein said mixture is administered for at least 15 days.
Claim 5
Dependent Claim 14 words
The method according to claim 1 wherein said mixture is administered for 60 days.
Claim 6
Dependent Claim 20 words
The method according to claim 1 wherein body fat deposition in said mammal is effectively reduced by administering said mixture.
Claim 7
Dependent Claim 20 words
The method according to claim 1 wherein glycogen concentration in said mammal is increased above normal by administering said mixture.
Claim 8
Dependent Claim 27 words
The method according to claim 1, 4, 5 or 6 wherein the rate of hepatic triglyceride generation in said mammal is effectively reduced by administering said mixture.
Claim 9
Independent Claim 39 words
A method for increasing the glycogen concentration in the liver of a mammal, which comprises administering orally to said mammal effective amounts of a mixture of pyruvate and dihydroxyacetone for a period sufficient to increase glycogen concentration above normal.
Claim 10
Independent Claim 39 words
A method for increasing the glycogen concentration in the liver of a mammal, which comprises administering orally to said mammal effective amounts of a mixture of pyruvate and dihydroxyacetone for a period sufficient to increase glycogen concentration above normal.
Claim 11
Dependent Claim 22 words
The method of claim 8 wherein the agent is administered to athletes prior to strenuous athletic events to increase endurance and/or performance.

References Cited (Backward Citations)

US4158057A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1985-09-27 1986-03-29 1986-09-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1989-09-27 1990-03-29 1990-09-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1993-09-27 1994-03-29 1994-09-28 $7700.00 Window Closed / Lapsed

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