US4351829A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Use of polypeptides as analgesic drugs
Assignee: Pfizer Italia SRL
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Filing: 1980-09-26
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Granted: 1982-09-28
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Expires: 2000-09-26
Abstract
Abstract A method of treating pain of whatever origin and nature in human and animal which comprises administering to the patient in need an effective amount of a polypeptide of structure: ##STR1## wherein X is selected from the group consisting of hydrogen, t-butyloxycarbonyl(Boc), Asp, Pyr--Glu, Pyr--Gln--Asp, Pyr--Asn--Asp; Y is selected from the group consisting of Thr, Met, Leu, Nle, Val; W is selected from the group consisting of Met, Nle, Leu.
Inventors
- 👤 Gerhard Zetler
- 👤 Alessandro Rossi
- 👤 Chiara De Paolis
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 04:48
CPC Classifications
C; C07; C07K; C07K5/00; C07K5/04; C07K5/10; C07K5/1021; A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/22; A61K38/2207; C07K14/00; C07K14/435; C07K14/575; C07K14/595
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
66 words
A method of inducing analgesia in animal and human patients suffering from severe pains selected from biliary and renal colic pains, pains caused by peripheral vascular diseases of the extremities, migraine chronic pains in cancer diseases, post-operatory-, traumatological-, large burns-, myocardial infarction- and angina pectoris pains, which comprises administering to the patient in need an effective amount of a polypeptide selected from ceruletide and salts thereof.
Claim 2
Independent Claim
66 words
A method of inducing analgesia in animal and human patients suffering from severe pains selected from biliary and renal colic pains, pains caused by peripheral vascular diseases of the extremities, migraine chronic pains in cancer diseases, post-operatory-, traumatological-, large burns-, myocardial infarction- and angina pectoris pains, which comprises administering to the patient in need an effective amount of a polypeptide selected from ceruletide and salts thereof.
Claim 3
Dependent Claim
15 words
A method in accordance with claim 1 wherein the polypeptide is administered by parenteral route.
Claim 4
Dependent Claim
16 words
A method in accordance with claim 2, wherein the polypeptide used is Ceruletide and salts thereof.
Claim 5
Dependent Claim
44 words
A method in accordance with claim 3, wherein Ceruletide is administered to the patient in need at a dose level of from 0.5 nanograms/kg body weight (i.v.) to 300 nanograms/kg body weight (intramusculary) in admixture with the usual carriers suitable for the parenteral administration.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-09-27 | 1986-03-29 | 1986-09-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-09-27 | 1990-03-29 | 1990-09-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-09-27 | 1994-03-29 | 1994-09-28 | $7700.00 | Window Closed / Lapsed |