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US4348399A
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Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives
Assignee: Wyeth Holdings LLC
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Filing: 1978-02-02
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Granted: 1982-09-07
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Expires: 1998-02-02
Abstract
Abstract This disclosure describes novel 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives useful as hypolipidemic and antiatherosclerotic agents.
Inventors
- 👤 Robert G. Shepherd
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-10 01:53
CPC Classifications
C; C07; C07D; C07D257/00; C07D257/02; C07D257/04; C07C; C07C275/00; C07C275/46; C07C275/48; C07C275/54; C07C45/00; C07C45/45; C07D295/00; C07D295/16; C07D295/18; C07D295/182; C07D295/192
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
120 words
A compound represented by the following structured formula: ##STR6## wherein X' is selected from the group consisting of an unbranched or branched C 1 -C 3 alkylene, C 2 -C 4 alkenylene, or ethynylene; Z' is selected from the group consisting of carboxyl, formyl, carbamoyl and COOR 3 wherein R 3 is selected from the group consisting C 1 -C 4 branched and unbranched alkyl, C 1 -C 3 alkoxyloweralkyl, di(C 1 -C 3 dialkyl)aminoloweralkyl, C 1 -C 3 mono- or dihydroxyalkyl, phenyl, halophenyl, 3-pyridyl, phenylmethyl, pyridylmethyl, C 3 -C 5 carboalkoxyalkyl, and C 2 -C 5 carboxyalkyl and R 1 is a branched or unbranched alkyl group C n H 2n+1 wherein n is an integer 13 to 17.
Claim 2
Dependent Claim
120 words
A compound represented by the following structured formula: ##STR6## wherein X' is selected from the group consisting of an unbranched or branched C 1 -C 3 alkylene, C 2 -C 4 alkenylene, or ethynylene; Z' is selected from the group consisting of carboxyl, formyl, carbamoyl and COOR 3 wherein R 3 is selected from the group consisting C 1 -C 4 branched and unbranched alkyl, C 1 -C 3 alkoxyloweralkyl, di(C 1 -C 3 dialkyl)aminoloweralkyl, C 1 -C 3 mono- or dihydroxyalkyl, phenyl, halophenyl, 3-pyridyl, phenylmethyl, pyridylmethyl, C 3 -C 5 carboalkoxyalkyl, and C 2 -C 5 carboxyalkyl and R 1 is a branched or unbranched alkyl group C n H 2n+1 wherein n is an integer 13 to 17.
Claim 3
Dependent Claim
8 words
A compound according to claim 1, 4-(hexadecylamino)phenylacetic acid.
Claim 4
Dependent Claim
8 words
A compound according to claim 1, 4-(tetradecylamino)phenylacetic acid.
Claim 5
Dependent Claim
4 words
A compound, 4-(octylamino)phenylacetic acid.
Claim 6
Dependent Claim
4 words
A compound, 4-(octylamino)phenylacetic acid.
Claim 7
Dependent Claim
8 words
A compound according to claim 3, 4-(hexadecylamino)hydrocinnamic acid.
Claim 8
Dependent Claim
4 words
A compound, ethyl 4-(N-hexadecylacetamido)hydrocinnamate.
Claim 9
Dependent Claim
4 words
A compound, ethyl 4-(N-hexadecylacetamido)hydrocinnamate.
Claim 10
Dependent Claim
4 words
A compound, 4-(hexadecylmethylamino)hydrocinnamic acid.
Claim 11
Dependent Claim
4 words
A compound, 4-(hexadecylmethylamino)hydrocinnamic acid.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-09-06 | 1986-03-08 | 1986-09-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-09-06 | 1990-03-08 | 1990-09-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-09-06 | 1994-03-08 | 1994-09-07 | $7700.00 | Window Closed / Lapsed |