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US4347251A
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Novel 3-substituted amino-1-substituted heteroaryl-2-pyrazolines
Assignee: Wyeth Holdings LLC
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Filing: 1981-07-13
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Granted: 1982-08-31
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Expires: 2001-07-13
Abstract
Abstract This disclosure describes novel 3-substituted amino-1-substituted heteroaryl-2-pyrazolines and their C 4 and C 5 analogs, effective as agents that ameliorate inflammation, analgesic agents, antibacterial agents and/or anti-fungal agents.
Inventors
- 👤 Joseph P. Joseph
- 👤 John P. Dusza
- 👤 Seymour Bernstein
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 16:10
CPC Classifications
C; C07; C07D; C07D213/00; C07D213/02; C07D213/04; C07D213/60; C07D213/72; C07D213/76; C07D213/77; C07C; C07C255/00; C07C47/00; C07C47/20; C07C47/21
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
49 words
A compound selected from the group consisting of those of the formula: ##STR5## wherein R 1 and R 2 may be hydrogen or lower alkyl (C 1 -C 4 ); R 3 is -COCH 3 or -CHO; X is halo or trifluoromethyl or a pharmacologically acceptable acid-addition salt thereof.
Claim 2
Dependent Claim
49 words
A compound selected from the group consisting of those of the formula: ##STR5## wherein R 1 and R 2 may be hydrogen or lower alkyl (C 1 -C 4 ); R 3 is -COCH 3 or -CHO; X is halo or trifluoromethyl or a pharmacologically acceptable acid-addition salt thereof.
Claim 3
Dependent Claim
7 words
The compound according to claim 1, N-[1-(6-chloro-2-pyridyl)-4-methyl-2-pyrazolin-3-yl]acetamide.
Claim 4
Dependent Claim
7 words
The compound according to claim 1, N-[1-(6-chloro-2-pyridyl)-5-ethyl-2-pyrazolin-3-yl]acetamide.
Claim 5
Dependent Claim
7 words
The compound according to claim 1, N-[1-(6-chloro-2-pyridyl)-2-pyrazolin-3-yl]acetamide.
Claim 6
Dependent Claim
7 words
The compound according to claim 1, N-[1-(6-chloro-2-pyridyl)-2-pyrazolin-3-yl]formamide.
Claim 7
Independent Claim
31 words
The method of meliorating inflammation in a mammal which comprises administering to said mammal an effective anti inflammatory amount of a compound according to claims 1, 2, 3, 4 or 5.
Claim 8
Dependent Claim
29 words
The method of treating pain in a mammal which comprises administering to said mammal an effective analgetic amount of a compound according to claim 1, 2, 3 or 4.
Claim 9
Independent Claim
34 words
The method of treating bacterial and/or fungal infections in a mammal which comprises administering to said mammal an effective antibacterial and/or antifungal amount of a compound according to claims 1, 2, 3 or 4.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-08-30 | 1986-03-01 | 1986-08-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-08-30 | 1990-03-01 | 1990-08-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-08-30 | 1994-03-01 | 1994-08-31 | $7700.00 | Window Closed / Lapsed |