Patent US366774A successfully refreshed from Google Patents.
Patent US4339437A successfully refreshed from Google Patents.
US4339437A
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US
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Anti-tumor method
Assignee: Research Corp
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Filing: 1979-07-26
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Granted: 1982-07-13
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Expires: 1999-07-26
Abstract
Abstract Malignant tumor cells sensitive to platinum coordination compounds in animals are treated by parenterally administering to an affected animal a solution containing a complex compound of platinum in an amount effective to cause regression of the tumor.
Inventors
- 👤 Barnett Rosenberg
- 👤 Loretta VanCamp
- 👤 Thomas Krigas
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 11:16
CPC Classifications
A; A61; A61K; A61K33/00; A61K33/24; A61K33/243
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
81 words
a method of treating animal malignant tumor cells sensitive to a planar dsp 2 platinum(II) coordination compound or an ochtahedral d 2 sp 3 platinum(IV) coordination compound wherein the donor ligands are Cl, Br, CN, NO 3 , ethylene diamine, propylene diamine, pyridine, H 2 O, OH, OS, in animals which comprises parenterally administering to an animal afflicted with said tumor cells a solution containing one of said compounds in an amount sufficient to cause regression of the animal tumor cells.
Claim 2
Independent Claim
81 words
a method of treating animal malignant tumor cells sensitive to a planar dsp 2 platinum(II) coordination compound or an ochtahedral d 2 sp 3 platinum(IV) coordination compound wherein the donor ligands are Cl, Br, CN, NO 3 , ethylene diamine, propylene diamine, pyridine, H 2 O, OH, OS, in animals which comprises parenterally administering to an animal afflicted with said tumor cells a solution containing one of said compounds in an amount sufficient to cause regression of the animal tumor cells.
Claim 3
Dependent Claim
14 words
A method according to claim 1 wherein the solution is administered in multiple doses.
Claim 4
Dependent Claim
15 words
A method according to claim 1 wherein the solution is administered in a single dose.
Claim 5
Dependent Claim
18 words
A method according to claim 1 wherein the compound is administered in a saline or salt-containing buffer solution.
Claim 6
Dependent Claim
12 words
A method according to claim 1 wherein the compound is a chloroplatinumammine.
Claim 7
Dependent Claim
17 words
A method according to claim 1 wherein the compound is cis-Pt(IV)(NH 3 ) 2 Cl 4 .
Claim 8
Dependent Claim
21 words
A method according to claim 1 wherein the compound is Pt(II)(NH 2 CH 2 CH 2 NH 2 )Cl 2 .
Claim 9
Dependent Claim
21 words
A method according to claim 1 wherein the compound is Pt(IV)(NH 2 CH 2 CH 2 NH 2 )Cl 4 .
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-07-12 | 1986-01-11 | 1986-07-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-07-12 | 1990-01-11 | 1990-07-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-07-12 | 1994-01-11 | 1994-07-13 | $7700.00 | Window Closed / Lapsed |