Patent US4338317A successfully refreshed from Google Patents.
US4338317A
Expired / Lapsed
US
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Phenoxyethyl-1,2,4,-triazol-3-one antidepressants
Assignee: Mead Johnson and Co LLC
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Filing: 1981-03-16
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Granted: 1982-07-06
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Expires: 2001-03-16
Abstract
Abstract Phenoxyethyl substituted-1,2,4,-triazolones having antidepressant properties typified by 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one are disclosed.
Inventors
- 👤 Davis L. Temple, Jr.
- 👤 Walter G. Lobeck, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:00
CPC Classifications
C; C07; C07D; C07D403/00; C07D403/02; C07D403/06; C07D295/00; C07D295/04; C07D295/06; C07D295/067; A; A61; A61P; A61P25/00; A61P25/20; A61P25/24; A61P25/26; C07D249/00; C07D249/02; C07D249/08; C07D249/10; C07D249/12
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
18 words
A compound of Formula I ##STR17## wherein R is halogen or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim
18 words
A compound of Formula I ##STR17## wherein R is halogen or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
8 words
The compound of claim 1 which is 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one.
Claim 4
Dependent Claim
9 words
The compound of claim 1 which is 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one hydrochloride.
Claim 5
Dependent Claim
33 words
The method for treating a mammal afflicted with depression comprising administering to said mammal a therapeutically effective antidepressant amount of a compound of claim 1 or a pharmaceutically acceptable acid addition salt thereof.
Claim 6
Dependent Claim
10 words
The method of claim 4 wherein the compound is 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one.
Claim 7
Dependent Claim
11 words
The method of claim 4 wherein the compound is 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one hydrochloride.
Claim 8
Dependent Claim
26 words
The pharmaceutical composition comprising an antidepressant amount of a compound of claim 1 or a pharmaceutically acceptable acid addition salt thereof and a pharmaceutically acceptable carrier.
Claim 9
Dependent Claim
11 words
The pharmaceutical composition of claim 7 wherein the compound is 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one.
Claim 10
Dependent Claim
12 words
The pharmaceutical composition of claim 7 wherein the compound is 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one hydrochloride.
References Cited (Backward Citations)
US3381009A
Cited
US3857845A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-07-05 | 1986-01-04 | 1986-07-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-07-05 | 1990-01-04 | 1990-07-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-07-05 | 1994-01-04 | 1994-07-06 | $7700.00 | Window Closed / Lapsed |