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US4338300A
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Use of purified clostridial collangenase in the treatment of Peyronie's disease
Assignee: University of California
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Filing: 1981-02-05
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Granted: 1982-07-06
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Expires: 2001-02-05
Abstract
Abstract The method of treating Peyronie's disease which comprises administering an effective amount of the enzyme collagenase directly into the plaques which form in the course of the disease.
Inventors
- 👤 Martin K. Gelbard
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 03:11
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/43; A61K38/46; A61K38/48; A61K38/4886
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
30 words
The method of treating Peyronie's disease in mammals which comprises administering an effective amount of the enzyme collagenase directly into the plaques which form in the course of the disease.
Claim 2
Independent Claim
30 words
The method of treating Peyronie's disease in mammals which comprises administering an effective amount of the enzyme collagenase directly into the plaques which form in the course of the disease.
Claim 3
Independent Claim
30 words
The method of treating Peyronie's disease in humans which comprises administering an effective amount of the enzyme collagenase directly into the plaques which form in the course of the disease.
Claim 4
Independent Claim
30 words
The method of treating Peyronie's disease in humans which comprises administering an effective amount of the enzyme collagenase directly into the plaques which form in the course of the disease.
Claim 5
Dependent Claim
17 words
The method of claim 2 wherein the collagenase is a mixture of Clostridiopeptidase A and Collagenase 2.
Claim 6
Dependent Claim
12 words
The method of claim 2 wherein the collagenase is lyophylized Clostridiopeptidase A.
Claim 7
Dependent Claim
15 words
The method of claim 2 wherein the collagenase is administered as a 0.5% buffered solution.
Claim 8
Dependent Claim
18 words
The method of claim 5 wherein the collagenase is administered in the range of 100 to 400 units.
Claim 9
Dependent Claim
11 words
The method of claim 5 wherein the collagenase is administered intralesionally.
References Cited (Backward Citations)
US4174389A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-07-05 | 1986-01-04 | 1986-07-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-07-05 | 1990-01-04 | 1990-07-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-07-05 | 1994-01-04 | 1994-07-06 | $7700.00 | Window Closed / Lapsed |