Patent US4332814A successfully refreshed from Google Patents.
US4332814A
Expired / Lapsed
US
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Treatment of diarrhoea
Assignee: Beecham Group PLC
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Filing: 1980-08-11
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Granted: 1982-06-01
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Expires: 2000-08-11
Abstract
Abstract Vasoconstrictor α-adrenergic agonists of formula (I) A--B--C (I) wherein, A is a 2-imidazoline group or a guanidine group; B is a chemical bond or a linking group one or two atoms in length; and C is a C 6-10 mono- or bi-cyclic group which is either an aromatic group, a heteroaromatic group containing only one hetero-atom, or a group containing an aromatic moiety; and which group C may be substituted by C 1-4 alkyl, C 1-4 alkoxy, halogen or hydroxyl; or salts thereof, are useful in the treatment and prevention of diarrhoea in livestock. Compositions of these compounds are described.
Inventors
- 👤 Peter M. Newsome
- 👤 Noel A. Mullen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 07:07
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/13; A61K31/155; A61K31/33; A61K31/395; A61K31/41; A61K31/415; A61P; A61P1/00; A61P1/12
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
89 words
A method for treating diarrhoea in livestock, which comprises administering to livestock an amount effective to treat diarrhoea of a compound which is an α-adrenergic agonist and which has vasoconstrictor activity and is further characterized by formula (I): A--B--C (I) wherein A is 2-imidazolinyl or guanidinyl; B is selected from a direct bond, --CH 2 --, --CH 2 O--, --COCH 2 -- or --NH--; and C is phenyl, naphthyl, tetrahydronaphthyl or benzothienyl, unsubstituted or substituted by C 1-4 alkyl, C 1-4 alkoxy, halogen or hydroxy, or a salt thereof.
Claim 2
Independent Claim
89 words
A method for treating diarrhoea in livestock, which comprises administering to livestock an amount effective to treat diarrhoea of a compound which is an α-adrenergic agonist and which has vasoconstrictor activity and is further characterized by formula (I): A--B--C (I) wherein A is 2-imidazolinyl or guanidinyl; B is selected from a direct bond, --CH 2 --, --CH 2 O--, --COCH 2 -- or --NH--; and C is phenyl, naphthyl, tetrahydronaphthyl or benzothienyl, unsubstituted or substituted by C 1-4 alkyl, C 1-4 alkoxy, halogen or hydroxy, or a salt thereof.
Claim 3
Dependent Claim
25 words
The method according to claim 1, wherein the compound of formula (I) is administered as a veterinary composition in association with a veterinarily acceptable carrier.
Claim 4
Dependent Claim
20 words
The method according to claim 1, wherein said compound of formula (I) is selected from the group consisting of ##STR24##
Claim 5
Dependent Claim
23 words
The method according to claim 1, wherein said compound of formula (I) is administered in foodstuff or drinking water provided for the livestock.
Claim 6
Dependent Claim
18 words
The method according to claim 2, wherein said carrier is an orally administrable oil or water based cream.
Claim 7
Dependent Claim
18 words
The method according to claim 2, wherein said compound of formula (I) is administered in water by injection.
Claim 8
Dependent Claim
25 words
The method according to claim 2, wherein said compound of formula (I) is administered in multidosage form containing at least 5 g. of said compound.
References Cited (Backward Citations)
CA1072962A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-05-31 | 1985-11-30 | 1986-06-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-05-31 | 1989-11-30 | 1990-06-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-05-31 | 1993-11-30 | 1994-06-01 | $7700.00 | Window Closed / Lapsed |