Patent US4331666A successfully refreshed from Google Patents.
US4331666A
Expired / Lapsed
US
⏱️ 0.0 years remaining
3-[(8-Carboxy-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4-thiazolyl)-2-methoxyimino-acetamido]-3-cephem-4-carboxylic acid
Assignee: Pfizer Italia SRL
•
Filing: 1980-04-08
•
Granted: 1982-05-25
•
Expires: 2000-04-08
Abstract
Abstract Heterocyclyl derivatives of oxy-imino-substituted cephalosporins are disclosed, such, for instance the compound 3-[(8-amino-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4 -thiazolyl)-2-methoxyimino-acetamido]-3-cephem-4-carboxylic acid and its pharmaceutically and veterinarily acceptable salts. The compounds of the application have high antibacterial activity against Gram-positive and Gram-negative bacteria, including strong beta-lactamase producer Gram-negative microorganisms.
Inventors
- 👤 Giuliano Nannini
- 👤 Ettore Perrone
- 👤 Ferruccio Casabuona
- 👤 Silvio Grasso
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-10 01:26
CPC Classifications
C; C07; C07D; C07D487/00; C07D487/02; C07D487/04; A; A61; A61P; A61P31/00; A61P31/04; C07C; C07C59/00; C07C59/185; C07C59/21; C07D237/00; C07D237/02; C07D237/06; C07D237/10; C07D237/24; Y; Y02; Y02P; Y02P20/00; Y02P20/50; Y02P20/55
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
9 words
3-[(8-carboxy-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido]-3-cephem-4-carboxylic acid and its pharmaceutically and veterinarily acceptable salts.
Claim 2
Dependent Claim
9 words
3-[(8-carboxy-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido]-3-cephem-4-carboxylic acid and its pharmaceutically and veterinarily acceptable salts.
Claim 3
Dependent Claim
10 words
3-[(8-carboxy-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido]-3-cephem-4-carboxylic acid (syn-isomer) and its pharmaceutically and veterinarily acceptable salts.
Claim 4
Dependent Claim
10 words
3-[(8-carboxy-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido]-3-cephem-4-carboxylic acid (syn-isomer) and its pharmaceutically and veterinarily acceptable salts.
Claim 5
Dependent Claim
30 words
Method of treating gram-positive or gram-negative bacteria infection in a patient, said method comprising administering to said patient a therapeutically effective amount of a compound of claim 1 or 2.
Claim 6
Dependent Claim
13 words
Method of claim 3, wherein said bacteria infection is a Gram-negative bacteria infection.
Claim 7
Dependent Claim
22 words
An anti-bacterial pharmaceutical or veterinary composition comprising a compound of claim 1 or 2 and a pharmaceutically or veterinarily acceptable carrier therefor.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-05-24 | 1985-11-23 | 1986-05-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-05-24 | 1989-11-23 | 1990-05-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-05-24 | 1993-11-23 | 1994-05-25 | $7700.00 | Window Closed / Lapsed |