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US4329185A
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Method for the preparation of a biologically active polyamide net
Assignee: Pharmachim DSO
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Filing: 1981-01-21
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Granted: 1982-05-11
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Expires: 2001-01-21
Abstract
Abstract A biologically creative polyamide net which is non-allergenic, non-carcinogenic, non-toxic and compatible with the human body is obtained by treating a polyamide net knit in a sequence of washing operations and activating the net with a solution of a antibacterial composition at elevated temperatures.
Inventors
- 👤 Kiril D. Dimov
- 👤 Nikelay B. Vassilev
- 👤 Dimiter G. Dimitrov
- 👤 Ekaterina I. Terlemezyan
- 👤 Angelina H. Georgieva
- 👤 Borislav A. Dimitrov
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 15:53
CPC Classifications
A; A61; A61L; A61L31/00; A61L31/14; A61L31/16; A61F; A61F2/00; A61F2/0063; A61L17/00; A61L17/06; A61L17/10; A61L31/04; A61L31/06; A61L2300/00; A61L2300/40; A61L2300/404
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
250 words
Method for the preparation of a biologically active polyamide net for insertion in the human body by means of a surgical intervention which comprises sequentially treating a knit of polyamide fibers of 5-10 Tex thickness and up to 500 twists per meter with cell dimensions of the order of 1.0/1.5×1.2/2.0 mm by: (a) washing said net with a nonionogenic medium at a temperature of from 20°-90° C. for a time period of from 5-30 minutes; (b) treating the net with boiling water for a time period ranging from 5-30 minutes; (c) treating the net with water at a temperature of 1°-30° C.; (d) treating the net with a solvent selected from the group consisting of acetone and an organic alcohol for a time period of from 5-30 minutes at room temperature while mixing the solvent; (e) washing the net with distilled water and draining it up to 50 percent residual humidity; (f) treating the net at a temperature within the range of 20°-90° C. for a time period ranging from 5-120 minutes with a non-allergenic, non-toxic and non-carcinogenic antibacterial composition selected from the group consisting of: (1) derivatives of 8-oxyquinoline; (2) derivatives of 8-oxyquinaldine; (3) nitrofuranic derivatives; and (4) metal salts of derivatives of 8-oxyquinolines, derivatives of 8-oxyquinaldines, or nitrofuranic derivatives. (g) washing the net with water at 5°-30° C. for a time period ranging from 5-30 minutes, and (h) drying the treated net at a temperature ranging from 20°-100° C. up to a residual humidity ranging from 2-5 percent.
Claim 2
Dependent Claim
250 words
Method for the preparation of a biologically active polyamide net for insertion in the human body by means of a surgical intervention which comprises sequentially treating a knit of polyamide fibers of 5-10 Tex thickness and up to 500 twists per meter with cell dimensions of the order of 1.0/1.5×1.2/2.0 mm by: (a) washing said net with a nonionogenic medium at a temperature of from 20°-90° C. for a time period of from 5-30 minutes; (b) treating the net with boiling water for a time period ranging from 5-30 minutes; (c) treating the net with water at a temperature of 1°-30° C.; (d) treating the net with a solvent selected from the group consisting of acetone and an organic alcohol for a time period of from 5-30 minutes at room temperature while mixing the solvent; (e) washing the net with distilled water and draining it up to 50 percent residual humidity; (f) treating the net at a temperature within the range of 20°-90° C. for a time period ranging from 5-120 minutes with a non-allergenic, non-toxic and non-carcinogenic antibacterial composition selected from the group consisting of: (1) derivatives of 8-oxyquinoline; (2) derivatives of 8-oxyquinaldine; (3) nitrofuranic derivatives; and (4) metal salts of derivatives of 8-oxyquinolines, derivatives of 8-oxyquinaldines, or nitrofuranic derivatives. (g) washing the net with water at 5°-30° C. for a time period ranging from 5-30 minutes, and (h) drying the treated net at a temperature ranging from 20°-100° C. up to a residual humidity ranging from 2-5 percent.
Claim 3
Dependent Claim
16 words
Method in accordance with claim 1 wherein said antibacterial composition is a potassium salt of 5-nitro-8-oxyquinaline.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-05-10 | 1985-11-09 | 1986-05-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-05-10 | 1989-11-09 | 1990-05-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-05-10 | 1993-11-09 | 1994-05-11 | $7700.00 | Window Closed / Lapsed |