US4311709A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Loweralkyl substituted diphenyl polyamine as an antimicrobial agent
Assignee: Merck and Co Inc
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Filing: 1979-12-26
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Granted: 1982-01-19
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Expires: 1999-12-26
Abstract
Abstract Loweralkyl substituted diphenyl polyamines are useful antimicrobial agents, as well as algae inhibitors. They are especially useful because of their low toxicity. One particular compound, 1-amino-3-{{3-[4-(1-methylethyl)-phenyl]-1-{2-[4-(methylethyl)-phenyl] ethyl}propyl}amino}-2-propanol, and salts thereof is particularly useful as an udder wash and teat dip for mastitis prevention in lactating cows. Compositions for such use are disclosed.
Inventors
- 👤 Richard A. Dybas
- 👤 Nathaniel Grier
- 👤 Bruce E. Witzel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 16:31
CPC Classifications
A; A01; A01N; A01N33/00; A01N33/02; A01N33/08; A61; A61K; A61K31/00; A61K31/13; A61K31/135; A61K9/00; A61K9/0012; A61K9/0041; A61P; A61P15/00; A61P15/14
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
38 words
A method for the prevention of mastitis in lactating dairy cows which comprises applying to either the udder, teats or both of such lactating dairy cows, a mastitis preventing effective amount of 1-amino-3-{{3-[4-(1-methylethyl)phenyl]-1-{2-[4-(1-methylethyl)phenyl]ethyl}propyl}amino]-2-propanol and pharmaceutically acceptable salts thereof.
Claim 2
Independent Claim
38 words
A method for the prevention of mastitis in lactating dairy cows which comprises applying to either the udder, teats or both of such lactating dairy cows, a mastitis preventing effective amount of 1-amino-3-{{3-[4-(1-methylethyl)phenyl]-1-{2-[4-(1-methylethyl)phenyl]ethyl}propyl}amino]-2-propanol and pharmaceutically acceptable salts thereof.
Claim 3
Dependent Claim
21 words
The method of claim 1 wherein the mastitis preventing compound is applied to the lactating dairy cows just prior to milking.
Claim 4
Dependent Claim
20 words
The method of claim 1 wherein the mastitis preventing compound is applied to the lactating dairy cows just after milking.
Claim 5
Dependent Claim
24 words
The method of claim 1 wherein the mastitis preventing compound is applied to the lactating dairy cows just prior to and just after milking.
Claim 6
Dependent Claim
22 words
The method of claim 1 wherein the mastitis preventing compounds are sprayed onto the udder and teats of the lactating dairy cow.
Claim 7
Dependent Claim
23 words
The method of claim 1 wherein the mastitis preventing compound is applied as a dip to the teats of the lactating dairy cow.
Claim 8
Dependent Claim
30 words
A composition useful for the prevention of mastitis in lactating dairy cows which comprises an inert carrier and a mastitis preventing effective amount of 1-amino-3-{{3-[4-(1-methylethyl)phenyl]-1-{2-[4-(1-methylethyl)phenyl]ethyl}propyl}amino]-2-propanol and pharmaceutically acceptable salts thereof.
Claim 9
Dependent Claim
30 words
A composition useful for the prevention of mastitis in lactating dairy cows which comprises an inert carrier and a mastitis preventing effective amount of 1-amino-3-{{3-[4-(1-methylethyl)phenyl]-1-{2-[4-(1-methylethyl)phenyl]ethyl}propyl}amino]-2-propanol and pharmaceutically acceptable salts thereof.
Claim 10
Dependent Claim
18 words
The composition of claim 7 which contains from 0.1 to 5% by weight of the mastitis preventing compound.
Claim 11
Dependent Claim
18 words
The composition of claim 8 which contains from 0.1 to 2% by weight of the mastitis preventing compound.
Claim 12
Dependent Claim
29 words
The composition of claim 7 which is a concentrate or premix to be diluted prior to use containing from 10 to 100% by weight of the mastitis preventing compound.
References Cited (Backward Citations)
US4172094A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-01-18 | 1985-07-20 | 1986-01-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-01-18 | 1989-07-20 | 1990-01-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-01-18 | 1993-07-20 | 1994-01-19 | $7700.00 | Window Closed / Lapsed |