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US4308253A Expired / Lapsed US ⏱️ 0.0 years remaining

Novel oral compositions for the care of the mouth and teeth

Assignee: Gaba Schweiz AG
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Filing: 1979-11-30
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Granted: 1981-12-29
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Expires: 1999-11-30
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Abstract

Abstract An oral composition for the care of the mouth and teeth which contains as an active ingredient, a compound of the formula: <IMAGE> (I) or <IMAGE> (II) or <IMAGE> (III) in which R1 and R2 in formulas I and II, may be the same or different and are selected from the group consisting of methyl, ethyl, chloroethyl, hydroxyethyl, aminoethyl, carbethoxymethyl, n-propyl, isopropyl, n-butyl, isobutyl, 1-methylpropyl, t-butyl, hexyl, cyclohexyl, methylcyclohexyl, benzyl, phenyl, chlorophenyl, methoxyphenyl, chloronitrophenyl or dimethylnitrophenyl.

Inventors

  • 👤 Hans Schmid
  • 👤 Hans R. Muhlemann

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 17:28
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/49

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 193 words
A toothpaste for the care of the mouth or teeth, for preventing plaque formation, paradentosis or caries consisting essentially of an effective antibacterial amount for preventing plaque formation, paradentosis or caries in the mouth of a compound of the formula: ##STR6## in which R 1 and R 2 in formulas I and II, may be the same or different and are selected from the group consisting of methyl, ethyl, chloroethyl, hydroxyethyl, aminoethyl, carbethoxymethyl, n-propyl, isopropyl, n-butyl, isobutyl, 1-methylpropyl, t-butyl, hexyl, cyclohexyl, methylcyclohexyl, benzyl, phenyl, chlorophenyl, methoxyphenyl, chloronitrophenyl or dimethylnitrophenyl; abrasives in an amount of 20-60 percent, said abrasives selected from the group consisting of dicalcium phosphate dihydrate, dicalcium phosphate anhydride, tricalcium phosphate, insoluble alkali metaphosphates, finely ground or colloidal silicon dioxides, aluminum oxide hydrates, aluminium silicates, aluminium magnesium silicates and alkaline earth carbonates; binders in an amount of 0.5 to 10 percent, said binders selected from the group consisting of water-soluble alginates, carragheenates, guar gum, tragacanth and water-soluble cellulose ethers selected from methyl cellulose, hydroxyalky cellulose and carboxymethyl cellulose, water-soluble salts of polyacrylic acids, Aerosils and bentonites; an effective amount of an anionic, nonionic and cationic detergent and the remainder being essentially water.
Claim 2
Dependent Claim 193 words
A toothpaste for the care of the mouth or teeth, for preventing plaque formation, paradentosis or caries consisting essentially of an effective antibacterial amount for preventing plaque formation, paradentosis or caries in the mouth of a compound of the formula: ##STR6## in which R 1 and R 2 in formulas I and II, may be the same or different and are selected from the group consisting of methyl, ethyl, chloroethyl, hydroxyethyl, aminoethyl, carbethoxymethyl, n-propyl, isopropyl, n-butyl, isobutyl, 1-methylpropyl, t-butyl, hexyl, cyclohexyl, methylcyclohexyl, benzyl, phenyl, chlorophenyl, methoxyphenyl, chloronitrophenyl or dimethylnitrophenyl; abrasives in an amount of 20-60 percent, said abrasives selected from the group consisting of dicalcium phosphate dihydrate, dicalcium phosphate anhydride, tricalcium phosphate, insoluble alkali metaphosphates, finely ground or colloidal silicon dioxides, aluminum oxide hydrates, aluminium silicates, aluminium magnesium silicates and alkaline earth carbonates; binders in an amount of 0.5 to 10 percent, said binders selected from the group consisting of water-soluble alginates, carragheenates, guar gum, tragacanth and water-soluble cellulose ethers selected from methyl cellulose, hydroxyalky cellulose and carboxymethyl cellulose, water-soluble salts of polyacrylic acids, Aerosils and bentonites; an effective amount of an anionic, nonionic and cationic detergent and the remainder being essentially water.
Claim 3
Dependent Claim 50 words
A toothpaste according to claim 1 consisting essentially of the following ingredients: ______________________________________ % ______________________________________ 2,4-di-n-butyl-perhydro-1,2,4-thiadiazine-1,1- dioxide 1.000 methyl cellulose 1.800 glycerol 20.000 dicalcium phosphate dihydrate 30.000 dicalcium phosphate anhydride 5.000 Na lauryl sarcosinate 2.000 saccharin 0.100 preservative (hydroxybenzoic acid methyl ester) 0.150 aroma agents 1.500 water to 100.00 ______________________________________
Claim 4
Dependent Claim 31 words
A mouth rinse consisting essentially of the following ingredients: ______________________________________ % ______________________________________ perhydro-1,2,4-thiadiazine-1,1-dioxide 0.500 aroma agents 0.070 sodium saccharate 0.050 polyoxyethylene sorbitan monooleate (Emulsifier) 1.000 ethanol 20.000 water to 100.00 ______________________________________
Claim 5
Dependent Claim 31 words
A mouth rinse consisting essentially of the following ingredients: ______________________________________ % ______________________________________ perhydro-1,2,4-thiadiazine-1,1-dioxide 0.500 aroma agents 0.070 sodium saccharate 0.050 polyoxyethylene sorbitan monooleate (Emulsifier) 1.000 ethanol 20.000 water to 100.00 ______________________________________
Claim 6
Dependent Claim 26 words
A sucking tablet consisting essentially of the following ingredients: ______________________________________ % ______________________________________ perhydro-1,2,4-thiadiazine-1,1-dioxide 2.000 xylitol 20.000 sorbitol 73.800 magnesium stearate 4.000 aroma agents 0.200 100.000 ______________________________________
Claim 7
Dependent Claim 26 words
A sucking tablet consisting essentially of the following ingredients: ______________________________________ % ______________________________________ perhydro-1,2,4-thiadiazine-1,1-dioxide 2.000 xylitol 20.000 sorbitol 73.800 magnesium stearate 4.000 aroma agents 0.200 100.000 ______________________________________

References Cited (Backward Citations)

FR4914M Cited
GB1124285A Cited
GB1385318A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1984-12-28 1985-06-29 1985-12-29 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1988-12-28 1989-06-29 1989-12-29 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1992-12-28 1993-06-29 1993-12-29 $7700.00 Window Closed / Lapsed

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