Patent US4308202A successfully refreshed from Google Patents.
US4308202A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Prolylphenylalanylarginine derivatives, process for producing same and method for measuring activity of enzymes using same
Assignee: Torii and Co Ltd
•
Filing: 1979-10-25
•
Granted: 1981-12-29
•
Expires: 1999-10-25
Abstract
Abstract A prolylphenylalanylarginine derivative represented by the formula, ##STR1## wherein R 1 represents hydrogen or benzoyl; R 2 represents naphthyl or 6-bromo-2-naphthyl. The above compound is useful as an excellent substrate for various enzymes, such as trypsin, plasmin, kallikrein, urokinase, Clesterase and the like. Accordingly, the activity of enzymes can be measured by use of said compound as a substrate.
Inventors
- 👤 Setsuro Fujii
- 👤 Mamoru Sugimoto
- 👤 Takashi Yaegashi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 18:04
CPC Classifications
C; C07; C07K; C07K5/00; C07K5/04; C07K5/08; C07K5/0821; C07K5/0823; C12; C12Q; C12Q1/00; C12Q1/34; C12Q1/37; Y; Y10; Y10S; Y10S530/00; Y10S530/802
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
22 words
A prolylphenylalanylarginine derivative represented by the formula, ##STR11## wherein R 1 represents hydrogen or benzoyl; and R 2 represents naphthyl or 6-bromo-2-naphthyl.
Claim 2
Dependent Claim
22 words
A prolylphenylalanylarginine derivative represented by the formula, ##STR11## wherein R 1 represents hydrogen or benzoyl; and R 2 represents naphthyl or 6-bromo-2-naphthyl.
Claim 3
Dependent Claim
3 words
L-prolyl-L-phenylalanyl-L-arginine 1-naphthyl ester.
Claim 4
Dependent Claim
3 words
L-prolyl-L-phenylalanyl-L-arginine 1-naphthyl ester.
Claim 5
Dependent Claim
3 words
Benzoyl-L-prolyl-L-phenylalanyl-L-arginine 1-naphthyl ester.
Claim 6
Dependent Claim
3 words
Benzoyl-L-prolyl-L-phenylalanyl-L-arginine 1-naphthyl ester.
Claim 7
Dependent Claim
3 words
L-prolyl-L-phenylalanyl-L-arginine 6-bromo-2-naphthyl ester.
Claim 8
Dependent Claim
3 words
L-prolyl-L-phenylalanyl-L-arginine 6-bromo-2-naphthyl ester.
Claim 9
Dependent Claim
3 words
Benzoyl-L-prolyl-L-phenylalanyl-L-arginine 6-bromo-2-naphthyl ester.
Claim 10
Dependent Claim
3 words
Benzoyl-L-prolyl-L-phenylalanyl-L-arginine 6-bromo-2-naphthyl ester.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-12-28 | 1985-06-29 | 1985-12-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-12-28 | 1989-06-29 | 1989-12-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-12-28 | 1993-06-29 | 1993-12-29 | $7700.00 | Window Closed / Lapsed |