US4298611A
Expired / Lapsed
US
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Process for reducing blood pressure in animals
Assignee: Massachusetts Institute of Technology
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Filing: 1978-04-24
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Granted: 1981-11-03
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Expires: 1998-04-24
Abstract
Abstract Blood pressure in animals is reduced by administering 2-chloro-6-methylergoline-8 beta -acetonitrile (lergotrile*) or pharmaceutically acceptable salts thereof either alone or in combination with a substance which is known to reduce blood pressure. A novel composition is provided comprising a unit dosage form of lergotrile and a substance which is known to reduce blood pressure. (* The term "lergotrile" is intended to include the compound lergotrile as well as its physiologically- and pharmacologically-active metabolites in the body.
Inventors
- 👤 John D. Fernstrom
- 👤 Alan F. Sved
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 05:01
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/47; A61K31/48; A61P; A61P9/00; A61P9/12
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
47 words
The process for reducing blood pressure in an animal suffering from high blood pressure which comprises administering a compound selected from the group consisting of 2-chloro-6-methylergoline-8Beta-acetonitrile, a pharmaceutically acceptable salt of 2-chloro-6 -methylergoline-8Beta-acetonitrile, and mixtures thereof to the animal in an amount effective to reduce blood pressure.
Claim 2
Dependent Claim
47 words
The process for reducing blood pressure in an animal suffering from high blood pressure which comprises administering a compound selected from the group consisting of 2-chloro-6-methylergoline-8Beta-acetonitrile, a pharmaceutically acceptable salt of 2-chloro-6 -methylergoline-8Beta-acetonitrile, and mixtures thereof to the animal in an amount effective to reduce blood pressure.
Claim 3
Dependent Claim
11 words
The process of claim 1 wherein the animal is a human.
References Cited (Backward Citations)
US4054660A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-11-02 | 1985-05-04 | 1985-11-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-11-02 | 1989-05-04 | 1989-11-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-11-02 | 1993-05-04 | 1993-11-03 | $7700.00 | Window Closed / Lapsed |