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US4297353A Expired / Lapsed US ⏱️ 0.0 years remaining

Non-irritating injectable dosage forms

Assignee: Sandoz Inc
•
Filing: 1980-08-04
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Granted: 1981-10-27
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Expires: 2000-08-04
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Abstract

Abstract A non-irritating injectable dosage form of a tissue irritating medicament, comprising the medicament and a pharmaceutically acceptable glyceride vehicle comprising a glycerol ester of a saturated or unsaturated fatty acid having from 6 to 20 carbon atoms or mixtures thereof.

Inventors

  • 👤 Hawkins V. Maulding

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-04 11:48
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K47/00; A61K47/06; A61K47/08; A61K47/14

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 76 words
Method of administering without irritation an injectable dosage form of a tissue irritating medicament, which comprises administering to a patient in need of the medicament, a therapeutically effective amount of thioridazine, in base form in association with a sufficient amount of a pharmaceutically acceptable glyceride vehicle comprising a glycerol ester of a saturated or unsaturated fatty acid which fatty acid has from 6 to 20 carbon atoms or mixtures thereof to form an injectable dosage form.
Claim 2
Dependent Claim 76 words
Method of administering without irritation an injectable dosage form of a tissue irritating medicament, which comprises administering to a patient in need of the medicament, a therapeutically effective amount of thioridazine, in base form in association with a sufficient amount of a pharmaceutically acceptable glyceride vehicle comprising a glycerol ester of a saturated or unsaturated fatty acid which fatty acid has from 6 to 20 carbon atoms or mixtures thereof to form an injectable dosage form.
Claim 3
Dependent Claim 18 words
The method according to claim 1 wherein the glyceride vehicle is sesame oil, corn oil or cottonseed oil.
Claim 4
Dependent Claim 31 words
The method according to claim 1 wherein the glyceride vehicle is a glycerol ester comprising a saturated vegetable fatty acid having substantially from 8 to 12 carbon atoms or mixtures thereof.
Claim 5
Dependent Claim 48 words
The method according to claim 1 wherein the glyceride vehicle has a fatty acid composition to about 3% hexanoic acid, from about 50 to 65% octanoic acid, from about 30 to about 45% decanoic acid and to about 5% lauric acid based on the weight of the glyceride.
Claim 6
Dependent Claim 45 words
Method of administering without irritation an injectable dosage form of a tissue irritating medicament, which comprises administering to a patient in need of the medicament, a therapeutically effective amount of thioridazine, in base form in association with a sufficient amount of pharmaceutically acceptable sesame oil.
Claim 7
Dependent Claim 45 words
Method of administering without irritation an injectable dosage form of a tissue irritating medicament, which comprises administering to a patient in need of the medicament, a therapeutically effective amount of thioridazine, in base form in association with a sufficient amount of pharmaceutically acceptable sesame oil.
Claim 8
Dependent Claim 63 words
A non-irritating injectable dosage form of a tissue irritating medicament, which comprises a therapeutically effective amount of thioridazine, in base form in association with a sufficient amount of a pharmaceutically acceptable glyceride vehicle comprising a glycerol ester of a saturated or unsaturated fatty acid which fatty acid has from 6 to 20 carbon atoms or mixtures thereof to form the injectable dosage form.
Claim 9
Dependent Claim 63 words
A non-irritating injectable dosage form of a tissue irritating medicament, which comprises a therapeutically effective amount of thioridazine, in base form in association with a sufficient amount of a pharmaceutically acceptable glyceride vehicle comprising a glycerol ester of a saturated or unsaturated fatty acid which fatty acid has from 6 to 20 carbon atoms or mixtures thereof to form the injectable dosage form.
Claim 10
Dependent Claim 20 words
The injectable dosage form according to claim 6 wherein the glyceride vehicle is sesame oil, corn oil, or cottonseed oil.
Claim 11
Dependent Claim 33 words
The injectable dosage form according to claim 6 wherein the glyceride vehicle is a glycerol ester comprising a saturated vegetable fatty acid having substantially from 8 to 12 carbon atoms or mixtures thereof.
Claim 12
Dependent Claim 49 words
The injectable dosage form according to claim 6 wherein the glyceride vehicle has a fatty acid composition to about 3% hexanoic acid, from about 50 to 65% octanoic acid, from about 30 to 45% decanoic acid and to about 5% lauric acid based on the weight of the glyceride.
Claim 13
Dependent Claim 32 words
A non-irritating injectable dosage form of a tissue irritating medicament, which comprises a therapeutically effective amount of thioridazine, in base form in association with a sufficient amount of pharmaceutically acceptable sesame oil.
Claim 14
Dependent Claim 32 words
A non-irritating injectable dosage form of a tissue irritating medicament, which comprises a therapeutically effective amount of thioridazine, in base form in association with a sufficient amount of pharmaceutically acceptable sesame oil.

References Cited (Backward Citations)

US3194733A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1984-10-26 1985-04-27 1985-10-27 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1988-10-26 1989-04-27 1989-10-27 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1992-10-26 1993-04-27 1993-10-27 $7700.00 Window Closed / Lapsed

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