Patent US2259176A successfully refreshed from Google Patents.
US4297353A
Expired / Lapsed
US
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Non-irritating injectable dosage forms
Assignee: Sandoz Inc
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Filing: 1980-08-04
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Granted: 1981-10-27
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Expires: 2000-08-04
Abstract
Abstract A non-irritating injectable dosage form of a tissue irritating medicament, comprising the medicament and a pharmaceutically acceptable glyceride vehicle comprising a glycerol ester of a saturated or unsaturated fatty acid having from 6 to 20 carbon atoms or mixtures thereof.
Inventors
- 👤 Hawkins V. Maulding
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 10:51
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K47/00; A61K47/06; A61K47/08; A61K47/14
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
76 words
Method of administering without irritation an injectable dosage form of a tissue irritating medicament, which comprises administering to a patient in need of the medicament, a therapeutically effective amount of thioridazine, in base form in association with a sufficient amount of a pharmaceutically acceptable glyceride vehicle comprising a glycerol ester of a saturated or unsaturated fatty acid which fatty acid has from 6 to 20 carbon atoms or mixtures thereof to form an injectable dosage form.
Claim 2
Dependent Claim
76 words
Method of administering without irritation an injectable dosage form of a tissue irritating medicament, which comprises administering to a patient in need of the medicament, a therapeutically effective amount of thioridazine, in base form in association with a sufficient amount of a pharmaceutically acceptable glyceride vehicle comprising a glycerol ester of a saturated or unsaturated fatty acid which fatty acid has from 6 to 20 carbon atoms or mixtures thereof to form an injectable dosage form.
Claim 3
Dependent Claim
18 words
The method according to claim 1 wherein the glyceride vehicle is sesame oil, corn oil or cottonseed oil.
Claim 4
Dependent Claim
31 words
The method according to claim 1 wherein the glyceride vehicle is a glycerol ester comprising a saturated vegetable fatty acid having substantially from 8 to 12 carbon atoms or mixtures thereof.
Claim 5
Dependent Claim
48 words
The method according to claim 1 wherein the glyceride vehicle has a fatty acid composition to about 3% hexanoic acid, from about 50 to 65% octanoic acid, from about 30 to about 45% decanoic acid and to about 5% lauric acid based on the weight of the glyceride.
Claim 6
Dependent Claim
45 words
Method of administering without irritation an injectable dosage form of a tissue irritating medicament, which comprises administering to a patient in need of the medicament, a therapeutically effective amount of thioridazine, in base form in association with a sufficient amount of pharmaceutically acceptable sesame oil.
Claim 7
Dependent Claim
45 words
Method of administering without irritation an injectable dosage form of a tissue irritating medicament, which comprises administering to a patient in need of the medicament, a therapeutically effective amount of thioridazine, in base form in association with a sufficient amount of pharmaceutically acceptable sesame oil.
Claim 8
Dependent Claim
63 words
A non-irritating injectable dosage form of a tissue irritating medicament, which comprises a therapeutically effective amount of thioridazine, in base form in association with a sufficient amount of a pharmaceutically acceptable glyceride vehicle comprising a glycerol ester of a saturated or unsaturated fatty acid which fatty acid has from 6 to 20 carbon atoms or mixtures thereof to form the injectable dosage form.
Claim 9
Dependent Claim
63 words
A non-irritating injectable dosage form of a tissue irritating medicament, which comprises a therapeutically effective amount of thioridazine, in base form in association with a sufficient amount of a pharmaceutically acceptable glyceride vehicle comprising a glycerol ester of a saturated or unsaturated fatty acid which fatty acid has from 6 to 20 carbon atoms or mixtures thereof to form the injectable dosage form.
Claim 10
Dependent Claim
20 words
The injectable dosage form according to claim 6 wherein the glyceride vehicle is sesame oil, corn oil, or cottonseed oil.
Claim 11
Dependent Claim
33 words
The injectable dosage form according to claim 6 wherein the glyceride vehicle is a glycerol ester comprising a saturated vegetable fatty acid having substantially from 8 to 12 carbon atoms or mixtures thereof.
Claim 12
Dependent Claim
49 words
The injectable dosage form according to claim 6 wherein the glyceride vehicle has a fatty acid composition to about 3% hexanoic acid, from about 50 to 65% octanoic acid, from about 30 to 45% decanoic acid and to about 5% lauric acid based on the weight of the glyceride.
Claim 13
Dependent Claim
32 words
A non-irritating injectable dosage form of a tissue irritating medicament, which comprises a therapeutically effective amount of thioridazine, in base form in association with a sufficient amount of pharmaceutically acceptable sesame oil.
Claim 14
Dependent Claim
32 words
A non-irritating injectable dosage form of a tissue irritating medicament, which comprises a therapeutically effective amount of thioridazine, in base form in association with a sufficient amount of pharmaceutically acceptable sesame oil.
References Cited (Backward Citations)
US3194733A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-10-26 | 1985-04-27 | 1985-10-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-10-26 | 1989-04-27 | 1989-10-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-10-26 | 1993-04-27 | 1993-10-27 | $7700.00 | Window Closed / Lapsed |