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US4296100A Expired / Lapsed US ⏱️ 0.0 years remaining

Method of treating the heart for myocardial infarction

Assignee: Individual
•
Filing: 1980-06-30
•
Granted: 1981-10-20
•
Expires: 2000-06-30
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Abstract

Abstract The heart is treated with fibroblast growth factor to alleviate conditions caused by myocardial infarctions as by reducing the size of damaged heart areas. An effective dose of fibroblast growth factor when applied to the heart is found to increase blood flow in affected areas for a period of at least 4 hours and often more.

Inventors

  • 👤 Wayne P. Franco

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-27 15:14
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/18; A61K38/1825; A61K9/00; A61K9/14; A61K9/16; A61K9/1605; A61K9/1629; A61K9/1652

Claims Analysis

Total Claims: 15
Claim 1
Independent Claim 44 words
A method of treating an area in the heart of a patient subjected to ischemic heart disease, to maintain viability in that area for a sustained time period to salvage said area, said method comprising applying an effective dose of FGF to the heart.
Claim 2
Independent Claim 44 words
A method of treating an area in the heart of a patient subjected to ischemic heart disease, to maintain viability in that area for a sustained time period to salvage said area, said method comprising applying an effective dose of FGF to the heart.
Claim 3
Dependent Claim 25 words
A method in accordance with the method of claim 1 wherein said patient is treated in vivo by direct injection of FGF in the heart.
Claim 4
Dependent Claim 20 words
A method in accordance with the method of claim 1 wherein said patient is treated by injecting said FGF intravenously.
Claim 5
Dependent Claim 27 words
A method in accordance with the method of claim 1 wherein said patient is treated by direct injection of 10 micrograms to 1 gram/100 grams of heart.
Claim 6
Dependent Claim 27 words
A method in accordance with the method of claim 2 wherein said patient is treated by direct injection of 10 micrograms to 1 gram/100 grams of heart.
Claim 7
Dependent Claim 27 words
A method in accordance with the method of claim 4 wherein said patient is treatd by direct injection of 10 micrograms to 1 gram/100 grams of heart.
Claim 8
Dependent Claim 30 words
A method in accordance with the method of claim 2 wherein blood flow in said area is increased over that which would occur in the area without treatment with FGF.
Claim 9
Dependent Claim 36 words
A method in accordance with the method of claim 1 wherein said FGF is applied by a method selected from the group consisting essentially of oral ingestion, subcutaneous injection, intramuscular injection, myocardial injection and intravenous injection.
Claim 10
Dependent Claim 22 words
A method in accordance with the method of claim 4 wherein said injection is of FGF carried in a slow release material.
Claim 11
Dependent Claim 22 words
A method in accordance with the method of claim 5 wherein said injection is of FGF carried in a slow release material.
Claim 12
Dependent Claim 22 words
A method in accordance with the method of claim 6 wherein said injection is of FGF carried in a slow release material.
Claim 13
Dependent Claim 19 words
A method in accordance with the method of claim 1 wherein said dose is administered during open heart surgery.
Claim 14
Independent Claim 35 words
A method of treating a coronary patient to affect the heart of the patient, said method comprising applying an effective dose of FGF to the patient so as to treat the heart of the patient.
Claim 15
Independent Claim 35 words
A method of treating a coronary patient to affect the heart of the patient, said method comprising applying an effective dose of FGF to the patient so as to treat the heart of the patient.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1984-10-19 1985-04-20 1985-10-20 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1988-10-19 1989-04-20 1989-10-20 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1992-10-19 1993-04-20 1993-10-20 $7700.00 Window Closed / Lapsed

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