US4293415A
Expired / Lapsed
US
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Silica chromatographic column
Assignee: HP Inc
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Filing: 1979-04-27
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Granted: 1981-10-06
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Expires: 1999-04-27
Abstract
Abstract An open tubular or capillary chromatographic column made from drawn silica tubing having an exterior coating for protection from abrasion and moisture and means for holding it in a desired configuration.
Inventors
- 👤 Paul F. Bente, III
- 👤 Ernest H. Zerenner
- 👤 Raymond D. Dandeneau
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 12:57
CPC Classifications
G; G01; G01N; G01N30/00; G01N30/02; G01N30/50; G01N30/56; G01N30/60; G01N30/6052; G01N30/6073; G01N30/6078; G01N2030/567; Y; Y10; Y10S; Y10S65/00; Y10S65/08
Claims Analysis
Total Claims: 27
Claim 1
Independent Claim
79 words
A chromatographic column for separating components of sample material flowing through it, comprising a hollow tube of drawn silica of thin wall construction with a high degree of flexibility, the inner surface of said tube being coated with a stationary phase material and there being an unobstructed passage along the axis of the tube, and a coating formed on the outer surface of the tube as it is drawn for protecting the said outer surface from abrasion and moisture.
Claim 2
Dependent Claim
79 words
A chromatographic column for separating components of sample material flowing through it, comprising a hollow tube of drawn silica of thin wall construction with a high degree of flexibility, the inner surface of said tube being coated with a stationary phase material and there being an unobstructed passage along the axis of the tube, and a coating formed on the outer surface of the tube as it is drawn for protecting the said outer surface from abrasion and moisture.
Claim 3
Dependent Claim
18 words
A chromatrographic column as set forth in claim 1 wherein the column has the configuration of a coil.
Claim 4
Dependent Claim
28 words
a chromatographic column as set forth in claim 1 wherein a deactivation treatment is applied to the inner surface of the tube before the stationary phase is applied.
Claim 5
Dependent Claim
22 words
A chromatographic column as set forth in claim 3 wherein said deactivation process is a treatment of the surface with an organochlorosilane.
Claim 6
Dependent Claim
22 words
A chromatorgraphic column as set forth in claim 3 wherein said deactivation process is a treatment of the surface with poly(ethylene oxide).
Claim 7
Dependent Claim
21 words
A chromatographic column as set forth in claim 3 wherein said deactivation process is a treatment of the surface with dimethyldichlorosilane.
Claim 8
Dependent Claim
21 words
A chromatographic column as set forth in claim 3 wherein said deactivation process is a treatment of the surface with trimethylchlorosilane.
Claim 9
Dependent Claim
21 words
A chromatographic column as set forth in claim 3 wherein said deactivation process is a treatment of the surface with hexamethyldisilazane.
Claim 10
Dependent Claim
22 words
A chromatographic column as set forth in claim 1 wherein said coating on the outside of said tube is comprised of polyimide.
Claim 11
Dependent Claim
23 words
A chromatographic column as set forth in claim 1 wherein said coating on the outside of said tube is comprised of silicone rubber.
Claim 12
Dependent Claim
33 words
A chromatographic column as set forth in claim 1 wherein said coating on the outside of said tube is comprised of a first layer of silicon nitride and a second layer of polyimide.
Claim 13
Dependent Claim
34 words
A chromatographic column as set forth in claim 1 wherein said coating on the outside of said tube is comprised of a first layer of silicon nitride and a second layer of silicone rubber.
Claim 14
Dependent Claim
22 words
A chromatographic column as set forth in claim 1 wherein said coating on the outside of said tube is comprised of metal.
Claim 15
Dependent Claim
81 words
A capillary chromatographic column, comprising a hollow tube of drawn silica, the inner surface of said tube having been deactivated, a coating of stationary phase material on said deactivated inner surface, there being an unobstructed passage along the axis of the tube, and a coating formed on the outer surface of the tube for protecting it from abrasion and moisture so that it is sufficiently flexible to be easily formed by hand into a coil having a diameter of 10 centimeters.
Claim 16
Dependent Claim
81 words
A capillary chromatographic column, comprising a hollow tube of drawn silica, the inner surface of said tube having been deactivated, a coating of stationary phase material on said deactivated inner surface, there being an unobstructed passage along the axis of the tube, and a coating formed on the outer surface of the tube for protecting it from abrasion and moisture so that it is sufficiently flexible to be easily formed by hand into a coil having a diameter of 10 centimeters.
Claim 17
Dependent Claim
22 words
A chromatographic column as set forth in claim 14 wherein said coating on the outside of said tube is comprised of polyimide.
Claim 18
Dependent Claim
23 words
A chromatographic column as set forth in claim 14 wherein said coating on the outside of said tube is comprised of silicone rubber.
Claim 19
Dependent Claim
33 words
A chromatographic column as set forth in claim 14 wherein said coating on the outside of said tube is comprised of a first layer of silicon nitride and a second layer of polyimide.
Claim 20
Dependent Claim
34 words
A chromatographic column as set forth in claim 14 wherein said coating on the outside of said tube is comprised of a first layer of silicon nitride and a second layer of silicone rubber.
Claim 21
Dependent Claim
22 words
A chromatographic column as set forth in claim 14 wherein said coating on the outside of said tube is comprised of metal.
Claim 22
Dependent Claim
107 words
Tubing for a capillary chromatographic column, comprising a hollow tube of drawn quartz, stationary phase material coated along the inner surface of said tube, there being an unobstructed passageway along the axis of said tube, a coating formed on the outside surface of said tube as it is drawn that protects said outside surface from moisture and abrasion, the inner diameter of said tube being such as to provide desired chromatographic performance, and the outer diameter of said tube being less than 2.0 millimeters by an amount providing a wall thickness that permits coiling the tube by hand into a coil having a diameter of 15 centimeters.
Claim 23
Dependent Claim
107 words
Tubing for a capillary chromatographic column, comprising a hollow tube of drawn quartz, stationary phase material coated along the inner surface of said tube, there being an unobstructed passageway along the axis of said tube, a coating formed on the outside surface of said tube as it is drawn that protects said outside surface from moisture and abrasion, the inner diameter of said tube being such as to provide desired chromatographic performance, and the outer diameter of said tube being less than 2.0 millimeters by an amount providing a wall thickness that permits coiling the tube by hand into a coil having a diameter of 15 centimeters.
Claim 24
Dependent Claim
85 words
A capillary chromatographic column comprising a hollow tube of drawn silica having an inner diameter within the range of 0.1 mm to 0.4 mm and an outer diameter within the range of 0.15 mm to 1.0 mm, the inner surface of said tube being coated with a stationary phase, and the outer surface of said tube having a coating formed thereon for protecting it from abrasion and moisture, whereby the column can be formed by hand into a coil having a diameter of 10 centimeters.
Claim 25
Dependent Claim
85 words
A capillary chromatographic column comprising a hollow tube of drawn silica having an inner diameter within the range of 0.1 mm to 0.4 mm and an outer diameter within the range of 0.15 mm to 1.0 mm, the inner surface of said tube being coated with a stationary phase, and the outer surface of said tube having a coating formed thereon for protecting it from abrasion and moisture, whereby the column can be formed by hand into a coil having a diameter of 10 centimeters.
Claim 26
Dependent Claim
25 words
A capillary column as set forth in claim 21 wherein said inner surface has been deactivated prior to the formation of the stationary phase thereon.
Claim 27
Dependent Claim
21 words
A capillary column as set forth in claim 21 wherein the coating on the outside surface of the tube is polyimide.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-10-05 | 1985-04-06 | 1985-10-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-10-05 | 1989-04-06 | 1989-10-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-10-05 | 1993-04-06 | 1993-10-06 | $7700.00 | Window Closed / Lapsed |