Patent US3344570A successfully refreshed from Google Patents.
Patent US4290962A successfully refreshed from Google Patents.
US4290962A
Expired / Lapsed
US
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Novel hydrocortisone derivative
Assignee: Taisho Pharmaceutical Co Ltd
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Filing: 1979-03-26
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Granted: 1981-09-22
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Expires: 1999-03-26
Abstract
Abstract 17α-butyryloxy-11β-hydroxy-21-propionyloxy-4-pregnen-3,20-dione, i.e., hydrocortisone 17-butyrate 21-propionate of the present invention is prepared by acylating hydrocortisone 17-butyrate with propionic acid anhydride or halide. The compound of the present invention has excellent anti-inflammatory effect, percutaneous absorption and less side effect.
Inventors
- 👤 Yasuhide Tachi
- 👤 Kazuhiko Michishita
- 👤 Jozi Nakagami
- 👤 Jiro Sawada
- 👤 Mitsunori Washitake
- 👤 Yoshiaki Kamano
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 10:48
CPC Classifications
C; C07; C07J; C07J21/00; A; A61; A61P; A61P29/00; A61P5/00; A61P5/38; C07J5/00; C07J5/0046; C07J5/0053
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
1 words
17α-butyryloxy-11β-hydroxy-21-propionyloxy-4-pregnen-3,20-dione.
Claim 2
Dependent Claim
1 words
17α-butyryloxy-11β-hydroxy-21-propionyloxy-4-pregnen-3,20-dione.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-09-21 | 1985-03-23 | 1985-09-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-09-21 | 1989-03-23 | 1989-09-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-09-21 | 1993-03-23 | 1993-09-22 | $7700.00 | Window Closed / Lapsed |