Patent FR853027A successfully refreshed from Google Patents.
Patent US1892192A successfully refreshed from Google Patents.
Patent US2195012A successfully refreshed from Google Patents.
Patent US4494870A successfully refreshed from Google Patents.
Patent US4288368A successfully refreshed from Google Patents.
US4288368A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Dithioacylproline derivatives
Assignee: ER Squibb and Sons LLC
•
Filing: 1979-07-30
•
Granted: 1981-09-08
•
Expires: 1999-07-30
Abstract
Abstract Compounds having the formula ##STR1## wherein: R 1 is hydrogen, alkyl, aryl or arylalkyl; R 2 is hydrogen and R 3 is hydrogen, hydroxy, alkoxy or halogen, or together R 2 and R 3 can be ═O or --X--(CH 2 ) t --X-- wherein X is oxygen or sulfur and t is 2 or 3; R 4 is hydrogen or alkyl; R 5 is hydrogen, alkyl or trifluoromethyl; R 6 is alkyl of 1 to 20 carbon atoms, aryl, arylalkyl or a 5- or 6-membered heterocyclic group having 1 or 2 nitrogen, sulfur or oxygen atoms in the ring; R 7 is aryl; m is 0, 1 or 2; and n is 1 or 2 have useful hypotensive activity.
Inventors
- 👤 Rudiger D. Haugwitz
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 00:00
CPC Classifications
C; C07; C07D; C07D231/00; C07D231/02; C07D231/06; A; A61; A61K; A61K31/00; A61K31/33; A61K31/38; A61K31/395; A61K31/40; A61K31/41; A61K31/415; A61P; A61P9/00; A61P9/12; C07D207/00; C07D207/02; C07D207/04; C07D207/10; C07D207/16
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
1 words
(S)-1-[2-Methyl-1-oxo-3-[(2-thienylthioxomethyl)-thio]propyl]-L-proline.
Claim 2
Dependent Claim
1 words
(S)-1-[2-Methyl-1-oxo-3-[(2-thienylthioxomethyl)-thio]propyl]-L-proline.
Claim 3
Dependent Claim
1 words
(S)-1-[2-Methyl-1-oxo-3-[(1-thioxooctadecyl)thio]-propyl]-L-proline.
Claim 4
Dependent Claim
1 words
(S)-1-[2-Methyl-1-oxo-3-[(1-thioxooctadecyl)thio]-propyl]-L-proline.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-09-07 | 1985-03-09 | 1985-09-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-09-07 | 1989-03-09 | 1989-09-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-09-07 | 1993-03-09 | 1993-09-08 | $7700.00 | Window Closed / Lapsed |