Anovulatory method and chicken feed compositions

Claim 2

An anovulatory composition comprising a solid poultry feedstuff having intimately dispersed therein at least an effective anovulatory amount of a compound of structural formula: ##STR14## or a non-toxic salt thereof, wherein: R is (1) C 1-4 alkyl, (2) C 2-5 alkenyl, (3) chloro, (4) bromo, or (5) iodo; R 1 and R 2 are independently (1) C 1-4 alkyl, (2) C 2-5 alkenyl, (3) chloro, (4) fluoro, (5) bromo, (6) iodo, (7) hydrogen, (8) nitro, (9) amino, (10) C 1-3 alkylamino, (11) di(C 1-3 alkyl)amino, (12) hydroxy, (13) carboxy, (14) C 1-3 alkoxycarbonyl, (15) C 1-4 alkanoyl, (16) C 1-4 alkylthio, (17) trifluoromethylthio, (18) phenylthio, (19) C 1-3 alkylphenylthio (20) C 1-3 alkoxyphenylthio (21) chlorophenylthio, (22) bromophenylthio, (23) phenoxy, (24) C 1-3 alkylphenoxy, (25) C 1-3 alkoxyphenoxy, (26) chlorophenoxy, (27) bromophenoxy, (28) amino-C 1-4 alkyl, (29) C 1-3 alkylamino-C 1-4 alkyl, (30) di(C 1-3 alkyl)amino-C 1-4 alkyl, (31) hydroxy C 1-4 alkyl, or (32) C 1-3 alkoxy-C 1-4 alkyl.

Claim 3

The anovulatory composition of claim 1 wherein R is C 1-4 alkyl, one of R 1 and R 2 is hydrogen, and the other is C 1-4 alkyl, fluoro, chloro, or C 1-3 alkoxy-C 1-4 alkyl.

Claim 4

The anovulatory composition of claim 2 wherein the anovulatory compound is: 2-(2,6-dimethylphenylimino)imidazolidine, 2-(3-chloro-2-methylphenylimino)imidazolidine, 2-(6-chloro-2-methylphenylimino)imidazolidine, 2-(2-methyl-4-methoxymethylphenylimino) imidazolidine, or 2-(5-fluoro-2-methylphenylimino)imidazolidine or a non-toxic salt thereof.

Claim 5

The composition of claim 1, 2, or 3 wherein the anovulatory compound comprises from about 20 to about 500 parts per million by weight.

Claim 6

The composition of claim 2 or 3 wherein the anovulatory compound comprises from about 30 to about 250 parts per million by weight.

Claim 7

A poultry feed premix composition comprising a solid poultry feedstuff having intimately dispersed therein an anovulatory compound in sufficient amount so that after dilution to final poultry feed said feed contains an effective amount of the anovulatory compound of structural formula: ##STR15## or a non-toxic salt thereof, wherein: R is (1) C 1-4 alkyl, (2) C 2-5 alkenyl, (3) chloro, (4) bromo, or (5) iodo; R 1 and R 2 are independently (1) C 1-4 alkyl, (2) C 2-5 alkenyl, (3) chloro, (4) fluoro, (5) bromo, (6) iodo, (7) hydrogen, (8) nitro, (9) amino, (10) C 1-3 alkylamino, (11) di(C 1-3 alkyl)amino, (12) hydroxy, (13) carboxy, (14) C 1-3 alkoxycarbonyl, (15) C 1-4 alkanoyl, (16) C 1-4 alkylthio, (17) trifluoromethylthio, (18) phenylthio, (19) C 1-3 alkylphenylthio (20) C 1-3 alkoxyphenylthio (21) chlorophenylthio, (22) bromophenylthio, (23) phenoxy, (24) C 1-3 alkylphenoxy, (25) C 1-3 alkoxyphenoxy, (26) chlorophenoxy, (27) bromophenoxy, (28) amino-C 1-4 alkyl, (29) C 1-3 alkylamino-C 1-4 alkyl, (30) di(C 1-3 alkyl)amino-C 1-4 alkyl, (31) hydroxy C 1-4 alkyl, or (32) C 1-3 alkoxy-C 1-4 alkyl.

Claim 8

A poultry feed premix composition comprising a solid poultry feedstuff having intimately dispersed therein an anovulatory compound in sufficient amount so that after dilution to final poultry feed said feed contains an effective amount of the anovulatory compound of structural formula: ##STR15## or a non-toxic salt thereof, wherein: R is (1) C 1-4 alkyl, (2) C 2-5 alkenyl, (3) chloro, (4) bromo, or (5) iodo; R 1 and R 2 are independently (1) C 1-4 alkyl, (2) C 2-5 alkenyl, (3) chloro, (4) fluoro, (5) bromo, (6) iodo, (7) hydrogen, (8) nitro, (9) amino, (10) C 1-3 alkylamino, (11) di(C 1-3 alkyl)amino, (12) hydroxy, (13) carboxy, (14) C 1-3 alkoxycarbonyl, (15) C 1-4 alkanoyl, (16) C 1-4 alkylthio, (17) trifluoromethylthio, (18) phenylthio, (19) C 1-3 alkylphenylthio (20) C 1-3 alkoxyphenylthio (21) chlorophenylthio, (22) bromophenylthio, (23) phenoxy, (24) C 1-3 alkylphenoxy, (25) C 1-3 alkoxyphenoxy, (26) chlorophenoxy, (27) bromophenoxy, (28) amino-C 1-4 alkyl, (29) C 1-3 alkylamino-C 1-4 alkyl, (30) di(C 1-3 alkyl)amino-C 1-4 alkyl, (31) hydroxy C 1-4 alkyl, or (32) C 1-3 alkoxy-C 1-4 alkyl.

Claim 9

The poultry feed premix of claim 6 wherein R is C 1-4 alkyl, one of R 1 and R 2 is hydrogen, and the other is C 1-4 alkyl, fluoro, chloro, or C 1-3 alkoxy-C 1-4 alkyl.

Claim 10

The poultry feed premix of claim 7, wherein the anovulatory compound is: 2-(2,6-dimethylphenylimino)imidazolidine, 2-(3-chloro-2-methylphenylimino)imidazolidine, 2-(6-chloro-2-methylphenylimino)imidazolidine, 2-(2-methyl-4-methoxymethylphenylimino) imidazolidine, or 2-(5-fluoro-2-methylphenylimino)imidazolidine or a non-toxic salt thereof.

Claim 11

The poultry feed premix of claim 6, 7 or 8 wherein the anovulatory agent comprises about 2 to about 50% by weight of the composition.

Claim 12

The poultry feed premix of claim 6, 7 or 8 wherein the anovulatory agent comprises about 5 to about 25% by weight of the composition.

Claim 15

The method of claim 11 wherein R is C 1-4 alkyl, one of R 1 and R 2 is hydrogen, and the other is C 1-4 alkyl, fluoro, chloro, or C 1-3 alkoxy-C 1-4 alkyl.

Claim 16

The method of claim 12 wherein the anovulatory compound is: 2-(2,6-dimethylphenylimino)imidazolidine, 2-(3-chloro-2-methylphenylimino)imidazolidine, 2-(6-chloro-2-methylphenylimino)imidazolidine, 2-(2-methyl-4-methoxymethylphenylimino) imidazolidine, or 2-(5-fluoro-2-methylphenylimino)imidazolidine or a non-toxic salt thereof.

Claim 17

The method of claim 11, 12 or 13 wherein the compound is administered orally as a component of the poultry feed, comprising from about 20 to about 500 parts per million by weight of the feed.

Claim 18

The method of claim 11, 12 or 13 wherein the compound is administered orally as a component of the poultry feed comprising from about 30 to about 250 parts per million by weight of the feed.

Claim 19

The method of claim 11, 12 or 13 wherein the compound or non-toxic salt thereof is administered orally as a component of drinking water comprising about 25 to about 100 parts per million by weight of the water.

Claim 20

The method of claim 11, 12 or 13 wherein the compound or non-toxic salt thereof is administered orally as a component of drinking water comprising about 25 to about 100 parts per million by weight of the water.

Claim 21

The method of claim 17 wherein the non-toxic salt is the hydrochloride.