US4283549A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of producing alkandiol-diaminobenzoates
Assignee: Saab Bofors AB
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Filing: 1978-12-04
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Granted: 1981-08-11
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Expires: 1998-12-04
Abstract
Abstract A method of producing alkandiol-diaminobenzoates which includes esterifying nitro-benzoic acid and certain diols in a melt and then dissolving the intermediate in a solvent sparingly soluble in water such as an aromatic hydrocarbon, an ether or an ester and reducing with hydrogen gas.
Inventors
- 👤 Boris Holm
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 12:04
CPC Classifications
C; C07; C07C; C07C201/00; C07C201/06; C07C201/12; C07C227/00; C07C227/04
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
57 words
A method of producing 1,3 propanediol-di-p-aminobenzoate from p-nitro-benzoic acid and 1,3 propanediol, characterized in that the nitrobenzoic acid and the diol are esterified in a melt at 160°-210° C. after which the intermediate obtained is dissolved in the solvent anisole and is reduced with hydrogen gas in the presence of said solvent to the amino compound desired.
Claim 2
Independent Claim
57 words
A method of producing 1,3 propanediol-di-p-aminobenzoate from p-nitro-benzoic acid and 1,3 propanediol, characterized in that the nitrobenzoic acid and the diol are esterified in a melt at 160°-210° C. after which the intermediate obtained is dissolved in the solvent anisole and is reduced with hydrogen gas in the presence of said solvent to the amino compound desired.
Claim 3
Dependent Claim
100 words
A method according to claim 1, characterized in that the nitrobenzoic acid is charged in a stoichiometric excess of up to 50%, and that the intermediate dissolved in the solvent is leached in water while adding a base selected from the group of sodium carbonate or sodium hydrogen carbonate in a stoichiometric excess compared with the original excess of nitrobenzoic acid and that the excess of nitrobenzoic acid is recovered from the sodium salt which is soluble in water thereby formed through acidification of the water separated from the solvent with the Na salt of the nitrobenzoic acid therein dissolved.
Claim 4
Dependent Claim
32 words
A method according to claim 1 or 2 characterized in that the desired amino compound is obtained from the solvent after this has been separated from the water through cooling and centrifuging.
Claim 5
Dependent Claim
68 words
A method according to claim 1 or 2 characterized in that the esterification of the nitro-benzoic acid with the diol is started up by all of the nitro-benzoic acid and solvent being added to the entire quantity of diol at one and the same time and that the temperature thereafter is successively raised while solvent and water formed at the reaction is successively permitted to be distilled off.
Claim 6
Dependent Claim
45 words
A method according to claim 1 or 2 characterized in that at the esterification the nitro-benzoic acid is charged in portions to the diol with good stirring and heating during such a long time that good stirring actually can take place during the entire process.
Claim 7
Dependent Claim
124 words
A method of producing 1,3-propanediol-di-p-aminobenzoate according to claim 1 or 2, characterized in that a stoichiometric excess of p-nitro-benzoic acid is esterified with 1,3-propanediol (trimethylene glycol) at a temperature of 160°-200° C., after which the product thereby obtained is dissolved in anisole and is leached in water while adding a stoichiometric excess of sodium carbonate or sodium hydrogen carbonate in relation to the excess of nitro-benzoic acid after which the solvent and water phases are separated from each other and the solvent phase then being reduced at 60°-130° C., with hydrogen gas while adding Pd/C as a catalyst and a hydrogen gas pressure of 2-12 kg/cm 2 , after which the product thereby obtained is isolated from the solvent phase through cooling and centrifuging.
Claim 8
Dependent Claim
18 words
The method of claim 2 wherein the nitrobenzoic acid is charged in a stoichiometric excess of about 10-25%.
Claim 9
Dependent Claim
66 words
A method according to claim 3 characterized in that the esterification of the nitro-benzoic acid with the diol is started up by all of the nitro-benzoic acid and solvent being added to the entire quantity of diol at one and the same time and that the temperature thereafter is successively raised while solvent and water formed at the reaction is successively permitted to be distilled off.
Claim 10
Dependent Claim
35 words
The method of claim 6 wherein the p-nitro-benzoic acid is esterified at a temperature of 180°-190° C.; wherein the temperature of reducing is 70°-90° C. and said hydrogen gas pressure is 5-10 kg/cm 2 .
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-08-10 | 1985-02-09 | 1985-08-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-08-10 | 1989-02-09 | 1989-08-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-08-10 | 1993-02-09 | 1993-08-11 | $7700.00 | Window Closed / Lapsed |