Integral partitioned hemodialysis unit

Claim 2

In a hemodialysis unit comprising a dialysis chamber having inlet and outlet dialysate ports and a pair of opposed sealed membrane sheets forming an integral blood perfusion unit having integral blood inlet and outlet ports, inlet and outlet blood manifolds, and multiple blood tubules disposed in parallel between said inlet and outlet manifolds, said integral blood perfusion unit having a length parallel to said parallel blood tubules, a width normal to said blood tubules, said membrane having high permeability to waste excreta products of patients, said blood perfusion unit disposed in the interior of said dialysis chamber, the combination comprising: the membrane exterior margins of said blood perfusion unit adaptively sized and interiorly secured at all said membrane exterior margins to the bonded edge of said dialysate chamber, said membrane exterior margins bonded and positioned to provide two separate dialysate subchambers, a first dialysate subchamber having a first exterior face of said blood perfusion unit providing a first subchamber floor, and a second dialysate subchamber having a second exterior opposed face of said blood perfusion unit providing a second subchamber ceiling, said two dialysate subchambers having the cross sectional areas of said two subchambers adaptively sized and adaptively positioned to provide a high velocity flow of dialysate solution over the length of said two subchambers, providing a rapid sweep of the diffusional boundary layer from the two opposed exterior face of the blood perfusion unit and providing a high rate of removal of waste excreta products from patient's blood.

Claim 3

In the hemodialysis unit set forth in claim 1, the further modification wherein, said two dialysate subchambers have a (cross sectional area width/combined height) ratio of at least 10/1 and greater.

Claim 4

In the hemodialysis unit set forth in claim 1, the further modification wherein, said two dialysate subchambers have a first single nozzle means having a septum providing a dialysate solution flow split input and a second single nozzle means providing dialysate solution output, the cross sectional areas of said two subchambers adaptively sized and said input and output solution single nozzles adaptively sized and positioned to provide a high velocity flow of dialysate solution over the length of each of said two subchambers, providing a high velocity sweep of the diffusional boundary layer from the two opposed exterior faces of the blood perfusion unit and providing a high rate of removal of waste excreta products from patient's blood.

Claim 5

In the hemodialysis unit set forth in claim 1, the further modification wherein, said two dialysate subchambers having one dialysate solution flow splitter input single nozzle secured at the septum extension of said input nozzle to said membrane exterior margin, and a solution output single nozzle, said input and output solution single nozzles adaptively sized and positioned to provide a high velocity equal volume flow of dialysate solution over the length of said two subchambers.

Claim 6

In a hemodialysis unit comprising a dialysis chamber having inlet and outlet dialysate ports and a pair of opposed sealed membrane sheets forming an integral blood perfusion unit having integral blood inlet and outlet ports, inlet and outlet blood manifolds, and multiple blood tubules disposed in parallel between said inlet and outlet manifolds, said integral blood perfusion unit having a length parallel to said parallel blood tubules, a width normal to said blood tubules, said membrane having high permeability to waste excreta products of patients, said blood perfusion unit disposed in the interior of said dialysis chamber, the combination comprising: said membrane exterior margins of said blood perfusion unit adaptively sized and interiorily secured at all said membrane exterior margins to the bonded edge of said dialysate chamber, said membrane exterior margins bonded and positioned to provide two separate dialysate subchambers, a first dialysate subchamber having a first exterior face of said blood perfusion unit providing a first subchamber floor, and a second dialysate subchamber having a second exterior opposed face of said blood perfusion unit providing a second subchamber ceiling, said two dialysate subchambers having one dialysate solution input nozzle having a septum providing a split dialysate solution input and one solution output nozzle, the cross sectional areas of said two subchambers adaptively sized and said input and output solution nozzles adaptively positioned to provide a high velocity flow of dialysate solution over the length of said two subchambers, providing a high velocity sweep of the diffusional boundary layer from the two opposed exterior faces of the blood perfusion unit and providing a high rate of removal of waste excreta products from patient's blood.

Claim 7

In a hemodialysis unit comprising a dialysis chamber having inlet and outlet dialysate ports and a pair of opposed sealed membrane sheets forming an integral blood perfusion unit having integral blood inlet and outlet ports, inlet and outlet blood manifolds, and multiple blood tubules disposed in parallel between said inlet and outlet manifolds, said integral blood perfusion unit having a length parallel to said parallel blood tubules, a width normal to said blood tubules, said membrane having high permeability to waste excreta products of patients, said blood perfusion unit disposed in the interior of said dialysis chamber, the combination comprising: said membrane exterior margins of said blood perfusion unit adaptively sized and interiorily secured at all said membrane exterior margins to the bonded edge of said dialysate chamber, said membrane exterior margins bonded and positioned to provide two separate dialysate subchambers, a first dialysate subchamber having a first exterior face of said blood perfusion unit providing a first subchamber floor, and a second dialysate subchamber having a second exterior opposed face of said blood perfusion unit providing a second subchamber ceiling, said two dialysate subchambers having one dialysate solution input nozzle having a septum providing a split dialysate solution input and one solution output nozzle, the cross sectional areas of said two subchambers adaptively sized and said input and output solution nozzles adaptively positioned to provide a high velocity flow of dialysate solution over the length of said two subchambers, providing a high velocity sweep of the diffusional boundary layer from the two opposed exterior faces of the blood perfusion unit and providing a high rate of removal of waste excreta products from patient's blood.

Claim 8

In a hemodialysis unit comprising a dialysis chamber having inlet and outlet dialysate ports and a pair of opposed sealed membrane sheets forming an integral blood perfusion unit having integral blood inlet and outlet ports, inlet and outlet blood manifolds, and multiple blood tubules disposed in parallel between said inlet and outlet manifolds, said integral blood perfusion unit having a length parallel to said parallel blood tubules, a width normal to said blood tubules, said membrane having high permeability to waste excreta products of patients, said blood perfusion unit disposed in the interior of said dialysis chamber, the combination comprising: said membrane exterior margins of said blood perfusion unit adaptively sized and interiorily secured at all said membrane exterior margins to the bonded edge of said dialysate chamber, said membrane exterior margins bonded and positioned to provide two separate dialysate subchambers, a first dialysate subchamber having a first exterior face of said blood perfusion unit providing a first subchamber floor, and a second dialysate subchamber having a second exterior opposed face of said blood perfusion unit providing a second subchamber ceiling, said two dialysate subchambers having the cross sectional areas of said two subchambers adaptively sized and adaptively positioned to provide a high velocity flow of dialysate solution over the length of said two subchambers, and, said two dialysate subchambers having one dialysate solution input nozzle having a septum providing a split dialysate solution input, and one solution output nozzle, said input and output solution nozzles adaptively positioned to provide a high velocity flow of dialysate solution over the length of said two subchambers, providing a high velocity sweep of the diffusional boundary layer from the two opposed exterior faces of the blood perfusion unit and providing a high rate of removal of waste excreta products from patient's blood.

Claim 9

In a hemodialysis unit comprising a dialysis chamber having inlet and outlet dialysate ports and a pair of opposed sealed membrane sheets forming an integral blood perfusion unit having integral blood inlet and outlet ports, inlet and outlet blood manifolds, and multiple blood tubules disposed in parallel between said inlet and outlet manifolds, said integral blood perfusion unit having a length parallel to said parallel blood tubules, a width normal to said blood tubules, said membrane having high permeability to waste excreta products of patients, said blood perfusion unit disposed in the interior of said dialysis chamber, the combination comprising: said membrane exterior margins of said blood perfusion unit adaptively sized and interiorily secured at all said membrane exterior margins to the bonded edge of said dialysate chamber, said membrane exterior margins bonded and positioned to provide two separate dialysate subchambers, a first dialysate subchamber having a first exterior face of said blood perfusion unit providing a first subchamber floor, and a second dialysate subchamber having a second exterior opposed face of said blood perfusion unit providing a second subchamber ceiling, said two dialysate subchambers having the cross sectional areas of said two subchambers adaptively sized and adaptively positioned to provide a high velocity flow of dialysate solution over the length of said two subchambers, and, said two dialysate subchambers having one dialysate solution input nozzle having a septum providing a split dialysate solution input, and one solution output nozzle, said input and output solution nozzles adaptively positioned to provide a high velocity flow of dialysate solution over the length of said two subchambers, providing a high velocity sweep of the diffusional boundary layer from the two opposed exterior faces of the blood perfusion unit and providing a high rate of removal of waste excreta products from patient's blood.