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US4278701A Expired / Lapsed US ⏱️ 0.0 years remaining

Animal and vegetal tissues permanently preserved by synthetic resin impregnation

Assignee: Individual
•
Filing: 1979-11-08
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Granted: 1981-07-14
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Expires: 1999-11-08
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Abstract

Abstract A solid, substantially anhydrous body essentially consisting of animal or vegetal tissue and a synthetic resin substantially uniformly distributed in the tissue is prepared from a water-bearing, normally soft tissue, subject to rapid decomposition and loss of weight by evaporation of its water content in air at 20° C., by substantially completely removing the water content while substantially maintaining the original tissue shape and volume, uniformly impregnating the water-free tissue with a fluid precursor composition capable of being polymerized into a solid synthetic resin, and holding the impregnated tissue under polymerization conditions until the precursor composition is cured to a solid resin more rigid than the original tissue.

Inventors

  • 👤 Gunther von Hagens

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 09:55
CPC Classifications
A; A01; A01N; A01N3/00; A01N1/00

Claims Analysis

Total Claims: 19
Claim 1
Independent Claim 124 words
A method of preparing a body consisting essentially of anhydrous animal or vegetal tissue and a water-insoluble synthetic resin substantially uniformly distributed in said tissue which comprises: (a) replacing the water content of a water-bearing body of animal or vegetal tissue with an organic solvent volatile in a vacuum; (b) holding said body bearing said solvent in contact with a fluid precursor composition in a vacuum until said solvent is volatilized and replaced in said body by said composition, said composition being capable of being polymerized into a solid, water-insoluble synthetic resin; (c) removing adhering precursor composition from the surface of said body; and (d) holding said body under polymerization conditions until said precursor composition in said body is cured to said solid resin.
Claim 2
Independent Claim 124 words
A method of preparing a body consisting essentially of anhydrous animal or vegetal tissue and a water-insoluble synthetic resin substantially uniformly distributed in said tissue which comprises: (a) replacing the water content of a water-bearing body of animal or vegetal tissue with an organic solvent volatile in a vacuum; (b) holding said body bearing said solvent in contact with a fluid precursor composition in a vacuum until said solvent is volatilized and replaced in said body by said composition, said composition being capable of being polymerized into a solid, water-insoluble synthetic resin; (c) removing adhering precursor composition from the surface of said body; and (d) holding said body under polymerization conditions until said precursor composition in said body is cured to said solid resin.
Claim 3
Dependent Claim 20 words
The method of claim 1 wherein the viscosity of said composition during said removing is not higher than 5000 cps.
Claim 4
Dependent Claim 26 words
The method of claim 1 wherein said body bearing said solvent is held in contact with said precursor composition by immersing the body in said composition.
Claim 5
Dependent Claim 41 words
The method of claim 1 wherein said tissue is an animal tissue including a vessel accessible to a hollow needle and permeable to said composition, said body being held in contact with said composition by injecting said composition into said vessel.
Claim 6
Dependent Claim 13 words
The method of claim 1 wherein said solid resin is a silicone rubber.
Claim 7
Independent Claim 113 words
A method of preparing a body consisting essentially of anhydrous animal or vegetal tissue and a water-insoluble synthetic resin substantially uniformly distributed in said tissue which comprises: (a) replacing the water content of a water-bearing body of animal or vegetal tissue with an organic solvent volatile in a vacuum; (b) holding said body bearing said solvent in contact with a fluid precursor composition in a vacuum until said solvent is volatilized and replaced in said body by said composition, said composition being capable of being polymerized into a solid, water-insoluble, synthetic resin; and (c) holding said body under polymerization conditions until said precursor composition in said body is cured to said solid resin.
Claim 8
Independent Claim 113 words
A method of preparing a body consisting essentially of anhydrous animal or vegetal tissue and a water-insoluble synthetic resin substantially uniformly distributed in said tissue which comprises: (a) replacing the water content of a water-bearing body of animal or vegetal tissue with an organic solvent volatile in a vacuum; (b) holding said body bearing said solvent in contact with a fluid precursor composition in a vacuum until said solvent is volatilized and replaced in said body by said composition, said composition being capable of being polymerized into a solid, water-insoluble, synthetic resin; and (c) holding said body under polymerization conditions until said precursor composition in said body is cured to said solid resin.
Claim 9
Dependent Claim 22 words
The method of claim 6 wherein the viscosity of said composition during said holding in contact is not higher than 5000 cps.
Claim 10
Dependent Claim 26 words
The method of claim 6 wherein said body bearing said solvent is held in contact with said precursor composition by immersing the body in said composition.
Claim 11
Dependent Claim 41 words
The method of claim 6 wherein said tissue is an animal tissue including a vessel accessible to a hollow needle and permeable to said composition, said body being held in contact with said composition by injecting said composition into said vessel.
Claim 12
Dependent Claim 12 words
The method of claim 6 wherein said vessel is a blood vessel.
Claim 13
Dependent Claim 13 words
The method of claim 6 wherein said solid resin is a silicone rubber.
Claim 14
Dependent Claim 39 words
The method of claim 6 wherein the amounts of said solvent being volatilized and of said composition being held in contact with said body are such that said composition is substantially completely absorbed and uniformly distributed in said body.
Claim 15
Dependent Claim 12 words
The method of claim 6 wherein said volatile organic solvent is dichloromethane.
Claim 16
Independent Claim 154 words
A method of preparing a body consisting essentially of anhydrous animal or vegetal tissue and a water-insoluble synthetic resin substantially uniformly distributed in said tissue which comprises: (a) replacing the water content of a water-bearing body of animal or vegetal tissue with an organic solvent volatile in a vacuum; (b) holding said body bearing said solvent in contact with a fluid precursor composition in a vacuum until said solvent is volatilized and replaced in said body by said composition, said composition being capable of being polymerized into a solid, water-insoluble, synthetic resin; (c) removing adhering precursor composition from the surface of said body; and (d) holding the body under polymerization conditions until said precursor composition in said body is cured to said solid resin, wherein said precursor composition includes another organic solvent substantially non-volatile in said vacuum and under said polymerization conditions, said other organic solvent being removed from said body after said curing.
Claim 17
Independent Claim 154 words
A method of preparing a body consisting essentially of anhydrous animal or vegetal tissue and a water-insoluble synthetic resin substantially uniformly distributed in said tissue which comprises: (a) replacing the water content of a water-bearing body of animal or vegetal tissue with an organic solvent volatile in a vacuum; (b) holding said body bearing said solvent in contact with a fluid precursor composition in a vacuum until said solvent is volatilized and replaced in said body by said composition, said composition being capable of being polymerized into a solid, water-insoluble, synthetic resin; (c) removing adhering precursor composition from the surface of said body; and (d) holding the body under polymerization conditions until said precursor composition in said body is cured to said solid resin, wherein said precursor composition includes another organic solvent substantially non-volatile in said vacuum and under said polymerization conditions, said other organic solvent being removed from said body after said curing.
Claim 18
Independent Claim 147 words
A method of preparing a body consisting essentially of anhydrous animal or vegetal tissue and a water-insoluble synthetic resin substantially uniformly distributed in said tissue which comprises: (a) replacing the water content of a water-bearing body of animal or vegetal tissue with an organic solvent volatile in a vacuum; (b) holding said body bearing said solvent in contact with a fluid precursor composition in a vacuum and at said temperature until said solvent is volatilized and replaced in said body by said composition, said composition being capable of being polymerized into a solid, water-insoluble, synthetic resin; and (c) holding said body under polymerization conditions until said precursor composition in said body is cured to said solid resin, wherein said precursor composition includes another organic solvent substantially non-volatile in said vacuum and under said polymerization conditions, said other organic solvent being removed from said body after said curing.
Claim 19
Independent Claim 147 words
A method of preparing a body consisting essentially of anhydrous animal or vegetal tissue and a water-insoluble synthetic resin substantially uniformly distributed in said tissue which comprises: (a) replacing the water content of a water-bearing body of animal or vegetal tissue with an organic solvent volatile in a vacuum; (b) holding said body bearing said solvent in contact with a fluid precursor composition in a vacuum and at said temperature until said solvent is volatilized and replaced in said body by said composition, said composition being capable of being polymerized into a solid, water-insoluble, synthetic resin; and (c) holding said body under polymerization conditions until said precursor composition in said body is cured to said solid resin, wherein said precursor composition includes another organic solvent substantially non-volatile in said vacuum and under said polymerization conditions, said other organic solvent being removed from said body after said curing.

References Cited (Backward Citations)

US2464512A Cited
US2658836A Cited
US2698809A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1984-07-13 1985-01-12 1985-07-14 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1988-07-13 1989-01-12 1989-07-14 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1992-07-13 1993-01-12 1993-07-14 $7700.00 Window Closed / Lapsed

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