Patent US4260610A successfully refreshed from Google Patents.
US4260610A
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Disubstituted piperazines
Assignee: Science Union et Cie
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Filing: 1978-11-03
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Granted: 1981-04-07
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Expires: 1998-11-03
Abstract
Abstract Disubstituted piperazines of the formula: ##STR1## in which: n is 1 or 2, X is oxygen and Y is sulfur or sulfonyl or X and Y are both sulfur or sulfonyl, and Het is a 5- or 6-membered heterocyclic radical having from 1 to 3 hetero atoms inclusive selected from nitrogen and sulfur and optionally substituted by one or more alkyl each having from 1 to 5 carbon atoms inclusive. These compounds may be used as medicines, especially in the treatment of central nervous system disorders and Parkinson's disease.
Inventors
- 👤 Gilbert Regnier
- 👤 Roger Canevari
- 👤 Michel Laubie
- 👤 Jean-Claude Poignant
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 09:16
CPC Classifications
C; C07; C07D; C07D327/00; C07D327/02; C07D327/04; A; A61; A61P; A61P25/00; A61P29/00; A61P9/00; A61P9/08; A61P9/12
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
14 words
A compound which is 1-[(2H)-1,3-benzoxathiol-5-yl methyl]-4-(thiazol-2-yl)piperazine or a physiologically tolerable acid addition salt thereof.
Claim 2
Dependent Claim
14 words
A compound which is 1-[(2H)-1,3-benzoxathiol-5-yl methyl]-4-(thiazol-2-yl)piperazine or a physiologically tolerable acid addition salt thereof.
Claim 3
Dependent Claim
14 words
A compound which is 1-[(2H)-1,3-benzoxathiol-5-yl methyl]-4-(1,3,4-thiadiazol-2-yl)piperazine or a physiologically tolerable acid addition salt thereof.
Claim 4
Dependent Claim
14 words
A compound which is 1-[(2H)-1,3-benzoxathiol-5-yl methyl]-4-(1,3,4-thiadiazol-2-yl)piperazine or a physiologically tolerable acid addition salt thereof.
Claim 5
Dependent Claim
14 words
A compound which is 1-[(2H)-1,3-benzoxathiol-5-yl methyl]-4-(pyrimidin-2-yl)piperazine or a physiologically tolerable acid addition salt thereof.
Claim 6
Dependent Claim
14 words
A compound which is 1-[(2H)-1,3-benzoxathiol-5-yl methyl]-4-(pyrimidin-2-yl)piperazine or a physiologically tolerable acid addition salt thereof.
Claim 7
Dependent Claim
26 words
A pharmaceutical composition containing as active ingredient a compound of claim 3 in an amount of 25 to 250 mg, together with a suitable pharmaceutical carrier.
Claim 8
Dependent Claim
37 words
A method for treating a living animal body afflicted with central nervous system disorders, comprising the step of administering an amount of a compound of claim 3 which is effective for the alleviation of the said conditions.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-04-06 | 1984-10-06 | 1985-04-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-04-06 | 1988-10-06 | 1989-04-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-04-06 | 1992-10-06 | 1993-04-07 | $7700.00 | Window Closed / Lapsed |