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US4258034A
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Lactobionic acid poly(H-sulfate) and salts thereof useful as complement inhibitors
Assignee: Wyeth Holdings LLC
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Filing: 1979-11-05
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Granted: 1981-03-24
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Expires: 1999-11-05
Abstract
Abstract Lactobionic acid poly(H-sulfate) and salts thereof, useful as complement inhibitors.
Inventors
- 👤 Joseph P. Joseph
- 👤 Seymour Bernstein
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 17:45
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/02; C07H15/04
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
20 words
A compound of the formula: ##STR2## wherein R is --SO 3 A; and A is a pharmaceutically acceptable salt cation.
Claim 2
Dependent Claim
20 words
A compound of the formula: ##STR2## wherein R is --SO 3 A; and A is a pharmaceutically acceptable salt cation.
Claim 3
Dependent Claim
12 words
The compound according to claim 1, lactobionic acid, octakis (H-sulfate) nonasodium salt.
Claim 4
Dependent Claim
12 words
The compound according to claim 1, lactobionic acid, octakis (H-sulfate) nonatrimethylamine salt.
Claim 5
Independent Claim
47 words
A method of inhibiting the complement system in a body fluid which comprises subjecting said body fluid to the action of an effective complement inhibiting amount of a compound of the formula: ##STR3## wherein R is --SO 3 A; and A is a pharmaceutically acceptable salt cation.
Claim 6
Independent Claim
47 words
A method of inhibiting the complement system in a body fluid which comprises subjecting said body fluid to the action of an effective complement inhibiting amount of a compound of the formula: ##STR3## wherein R is --SO 3 A; and A is a pharmaceutically acceptable salt cation.
Claim 7
Dependent Claim
13 words
A method according to claim 4, wherein the body fluid is blood serum.
Claim 8
Dependent Claim
16 words
A method according to claim 4, wherein the compound is lactobionic acid, octakis (H-sulfate nonasodium salt.
Claim 9
Dependent Claim
16 words
A method according to claim 4, wherein the compound is lactobionic acid, octakis (H-sulfate) nonatrimethylamine salt.
Claim 10
Independent Claim
43 words
A method of inhibiting the complement system in a warm-blooded animal which comprises administering to said animal an effective complement inhibiting amount of a compound of the formula: ##STR4## wherein R is --SO 3 A; and A is a pharmaceutically acceptable salt cation.
Claim 11
Independent Claim
43 words
A method of inhibiting the complement system in a warm-blooded animal which comprises administering to said animal an effective complement inhibiting amount of a compound of the formula: ##STR4## wherein R is --SO 3 A; and A is a pharmaceutically acceptable salt cation.
Claim 12
Dependent Claim
12 words
A method according to claim 8, wherein the compound is administered internally.
Claim 13
Dependent Claim
12 words
A method according to claim 8, wherein the compound is administered topically.
Claim 14
Dependent Claim
16 words
A method according to claim 8, wherein the compound is administered periodontally in the oral cavity.
Claim 15
Dependent Claim
12 words
A method according to claim 9, wherein the compound is administered intra-articularly.
Claim 16
Dependent Claim
16 words
A method according to claim 8, wherein the compound is lactobionic acid, octakis (H-sulfate) nonasodium salt.
Claim 17
Dependent Claim
16 words
A method according to claim 8, wherein the compound is lactobionic acid, octakis (H-sulfate) nonatrimethylamine salt.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-03-23 | 1984-09-22 | 1985-03-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-03-23 | 1988-09-22 | 1989-03-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-03-23 | 1992-09-22 | 1993-03-24 | $7700.00 | Window Closed / Lapsed |