US4251518A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of preparing readily disintegrable pharmaceutical compositions
Assignee: Nestle Purina PetCare Co
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Filing: 1979-07-03
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Granted: 1981-02-17
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Expires: 1999-07-03
Abstract
Abstract Soy polysaccharides, which are substantially high molecular weight cell wall structural components of soybean cotyledons, are mixed with a therapeutically-active substance and the mixture is made into a tablet by conventional means such as wet or dry granulation or direct compression procedures. The tablets obtained by this method have sufficient hardness and highly beneficial disintegration properties.
Inventors
- 👤 Wayne R. Moore
- 👤 Debra K. Mann
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 20:27
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/2004; A61K9/2022; A61K9/205
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
31 words
A method of preparing readily disintegrable pharmaceutical composition which comprises mixing a disintegratingly effective amount of soy polysaccharides with a therapeutically active substance and shaping said mixture into the desired form.
Claim 2
Independent Claim
31 words
A method of preparing readily disintegrable pharmaceutical composition which comprises mixing a disintegratingly effective amount of soy polysaccharides with a therapeutically active substance and shaping said mixture into the desired form.
Claim 3
Dependent Claim
28 words
The method of claim 1 wherein the soy polysaccharides are present in the mixture in an amount sufficient to provide from about 0.50 to about 15% by weight.
Claim 4
Dependent Claim
28 words
The method of claim 2 wherein the soy polysaccharides are present in the mixture in an amount sufficient to provide from about 1 to about 6% by weight.
Claim 5
Dependent Claim
19 words
The method of claim 1 where the soy polysaccharides are the aqueous alkaline insoluble residue from soy protein processing.
Claim 6
Dependent Claim
73 words
The method of claim 4 where the soy polysaccharides are substantially high molecular weight cell wall structural components of soybean cotyledons generally obtained by treating dehulled, defatted and desolventized material selected from the group consisting of soy meal, soy flakes and soy flour with an aqueous alkaline solution to solubilize and substantially remove aqueous alkaline soluble substances from the soy material, separating the extracted material from the extract and drying the extracted product.
Claim 7
Dependent Claim
28 words
The mthod of claim 1 wherein the soy polysaccharides have a Brookfield viscosity at 3% solids level and 25° C. of about 25 cps to about 45 cps.
Claim 8
Dependent Claim
21 words
The method of claim 1 wherein about 40% of the soy polysaccharides have a particle size smaller than about 37 microns.
Claim 9
Dependent Claim
13 words
The method of claim 1 wherein the pharmaceutical composition is a compressed tablet.
Claim 10
Independent Claim
41 words
A method of causing a pharmaceutical composition to disintegrate upon being administered to an animal, which comprises administering to the animal a pharmaceutical composition prepared from a mixture containing a therapeutically active substance and a disintegratingly effective amount of soy polysaccharides.
Claim 11
Independent Claim
41 words
A method of causing a pharmaceutical composition to disintegrate upon being administered to an animal, which comprises administering to the animal a pharmaceutical composition prepared from a mixture containing a therapeutically active substance and a disintegratingly effective amount of soy polysaccharides.
Claim 12
Dependent Claim
28 words
The method of claim 9 wherein the soy polysaccharides are present in the mixture in an amount sufficient to provide from about 0.50 to about 15% by weight.
Claim 13
Dependent Claim
28 words
The method of claim 9 wherein the soy polysaccharides are present in the mixture in an amount sufficient to provide from about 1 to about 6% by weight.
Claim 14
Dependent Claim
19 words
The method of claim 9 wherein the soy polysaccharides are the aqueous alkaline insoluble residue from soy protein processing.
Claim 15
Dependent Claim
66 words
The method of claim 12 where the soy polysaccharides are substantially high molecular weight cell wall structural components of soybean cotyledons generally obtained by treating dehulled, defatted and desolventized soy meal or flakes with an aqueous alkaline solution to solubilize and substantially remove aqueous alkaline soluble substances from the meal or flakes, separating the extracted meal or flakes from the extract and drying the extracted product.
Claim 16
Dependent Claim
28 words
The method of claim 9 wherein the soy polysaccharides have a Brookfield vicosity at 3% solids level and 25° C. of about 25 cps to about 45 cps.
Claim 17
Dependent Claim
21 words
The method of claim 9 wherein about 40% of the soy polysaccharides have a particle size smaller than about 37 microns.
Claim 18
Dependent Claim
13 words
The method of claim 9 wherein the pharmaceutical composition is a compressed tablet.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-02-17 | 1984-08-18 | 1985-02-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-02-17 | 1988-08-18 | 1989-02-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-02-17 | 1992-08-18 | 1993-02-17 | $7700.00 | Window Closed / Lapsed |