US4248867A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Stabilized oily preparation of 1α-hydroxy-vitamin D and method for manufacturing the same
Assignee: Chugai Pharmaceutical Co Ltd
•
Filing: 1978-06-14
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Granted: 1981-02-03
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Expires: 1998-06-14
Abstract
Abstract A stabilized oily preparation of a 1 alpha -hydroxy-vitamin D for oral administration comprising a 1 alpha -hydroxy-vitamin D and, as oily diluent, a triglyceride of saturated middle chain fatty acid which has been treated under certain conditions, and a method for manufacturing the same are disclosed.
Inventors
- 👤 Heizi Ikushima
- 👤 Kazuo Igusa
- 👤 Sadao Bessho
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 20:30
CPC Classifications
A; A61; A61K; A61K47/00; A61K47/06; A61K47/08; A61K47/14
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
34 words
A method for manufacturing a stabilized oily preparation which comprises irradiating a triglyceride of saturated middle chain fatty acid(s) with light longer than 290 nm, and dissolving a 1α-hydroxy-vitamin D in the treated triglyceride.
Claim 2
Independent Claim
34 words
A method for manufacturing a stabilized oily preparation which comprises irradiating a triglyceride of saturated middle chain fatty acid(s) with light longer than 290 nm, and dissolving a 1α-hydroxy-vitamin D in the treated triglyceride.
Claim 3
Dependent Claim
28 words
A method according to claim 1 wherein a light source of said light is selected from the group consisting of sunlight, xenon lamp, mercury lamp and fluorescent lamp.
Claim 4
Dependent Claim
14 words
A method according to claim 1 wherein said irradiation is effected for 1-60 hours.
Claim 5
Dependent Claim
23 words
A method according to claim 1 wherein said irradiating step takes place with said saturated middle chain fatty acid(s) under an inert atmosphere.
Claim 6
Dependent Claim
32 words
A method in accordance with claim 1 wherein said triglyceride is a triglyceride of saturated C 6 -C 12 middle chain fatty acid(s) and is liquid at room temperature under atmospheric pressure.
Claim 7
Dependent Claim
34 words
A method in accordance with claim 1, wherein said 1α-hydroxy-vitamin D is selected from the group consisting of 1α-hydroxy-vitamin D 3 , 1α,25-dihydroxy-vitamin D 3 , 1α,24-dihydroxy-vitamin D 3 and 1α,24,25-trihydroxy-vitamin D 3 .
Claim 8
Dependent Claim
34 words
A method in accordance with claim 5, wherein said 1α-hydroxy-vitamin D is selected from the group consisting of 1α-hydroxy-vitamin D 3 , 1α,25-dihydroxy-vitamin D 3 , 1α,24-dihydroxy-vitamin D 3 and 1,24,25-trihydroxy-vitamin D 3 .
Claim 9
Dependent Claim
20 words
A stabilized oily preparation produced in accordance with the process of claims 1, 2, 3, 4, 5, 6 or 7.
References Cited (Backward Citations)
US3149037A
Cited
US3901928A
Cited
JPS52128210A
Cited
FR2348697A1
Cited
JPS52130905A
Cited
JPS5312414A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-02-03 | 1984-08-04 | 1985-02-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-02-03 | 1988-08-04 | 1989-02-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-02-03 | 1992-08-04 | 1993-02-03 | $7700.00 | Window Closed / Lapsed |